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Showing 1 - 20 of 34 Items
Showing 1 - 20 of 34 Items
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Protocol

Evaluating the diagnostic accuracy of WHO-recommended treatment decision algorithms for childhood tuberculosis using an individual person dataset: a study protocol

Olbrich L, Larsson L, Dodd P, Palmer M, Nguyen MHTN,  et al.
2025-09-17 • BMJ Open
2025-09-17 • BMJ Open

INTRODUCTION

In 2022, the WHO conditionally recommended the use of treatment decision algorithms (TDAs) for treatment decision-making in children <10 years with...

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Research Protocol

Haematological dynamics following treatment of visceral leishmaniasis: a protocol for systematic review and individual participant data (IPD) meta-analysis

Munir A, Dahal P, Kumar R, Singh-Phulgenda S, Siddiqui NA,  et al.
2023-12-14 • BMJ Open
2023-12-14 • BMJ Open
INTRODUCTION
Visceral leishmaniasis (VL) is a parasitic disease with an estimated 30,000 new cases occurring annually. Despite anaemia being a common haematological manifestation of ...

Experiences and perceptions of urine sampling for tuberculosis testing among HIV patients: a multisite qualitative descriptive study

Lissouba P, Rücker SCM, Otieno LA, Akatukwasa C, Xulu S,  et al.
2023-11-30 • BMJ Open
2023-11-30 • BMJ Open
OBJECTIVES
Evidence on the acceptability of urine-based assays for tuberculosis (TB) diagnosis among patients remains limited. We sought to describe patients’ experiences and percept...

Host, parasite and drug determinants of clinical outcomes following treatment of visceral leishmaniasis: a protocol for individual participant data meta-analysis

Kumar R, Dahal P, Singh-Phulgenda S, Siddiqui NA, Munir A,  et al.
2023-10-28 • BMJ Open
2023-10-28 • BMJ Open
INTRODUCTION
Visceral leishmaniasis (VL) is a parasitic disease with an estimated 30 000 new cases occurring annually. There is an observed variation in the efficacy of the current f...

Responsible exit of humanitarian aid agencies at the end of programmes: a scoping review protocol

Bahati D, Sy H, Kalhor A, Marchal B
2023-08-23 • BMJ Open
2023-08-23 • BMJ Open
INTRODUCTION
In humanitarian settings, aid agencies are constantly challenged by difficult decisions such as when and how to terminate aid without harming the aid recipients, local i...

Point-of-care ultrasound for tuberculosis diagnosis in children: a Médecins Sans Frontières cross-sectional study in Guinea-Bissau

Moretó-Planas L, Sagrado MJ, Mahajan R, Gallo J, Biague E,  et al.
2023-05-19 • BMJ Open
2023-05-19 • BMJ Open
OBJECTIVE
Description of tuberculosis (TB)-focused point-of-care ultrasound (POCUS) findings for children with presumptive TB.

DESIGN
Cross-sectional study (July 2019 to...

Descriptive epidemiology of the cholera outbreak in Zimbabwe 2018–2019: role of multi-sectorial approach in cholera epidemic control

Mashe T, Chaibva BV, Nair P, Sani KA, Jallow M,  et al.
2023-01-30 • BMJ Open
2023-01-30 • BMJ Open
OBJECTIVES
This study was conducted to explore the epidemiology and microbiological pattern of the cholera outbreaks that occurred in Zimbabwe from 2018 to 2019.

STUDY SETTI...

Fixed dose combination drugs for cardiovascular disease in a prolonged humanitarian crisis in Lebanon: an implementation study

Ansbro É, Masri S, Prieto-Merino D, Willis R, Aoun Bahous S,  et al.
2023-01-25 • BMJ Open
2023-01-25 • BMJ Open
OBJECTIVES
This pre–post implementation study evaluated the introduction of fixed dose combination (FDC) medications for atherosclerotic cardiovascular disease (ASCVD) secondary prev...

COVID-19 in French nursing homes during the second pandemic wave: a mixed-methods cross-sectional study

Dujmovic M, Roederer T, Frison S, Melki C, Lauvin T,  et al.
2022-09-20 • BMJ Open
2022-09-20 • BMJ Open
INTRODUCTION
French nursing homes were deeply affected by the first wave of the COVID-19 pandemic, with 38% of all residents infected and 5% dying. Yet, little was done to prepare th...

Evaluating process and clinical outcomes of a primary care mental health integration project in rural Rwanda: a prospective mixed-methods protocol

Smith SL, Misago CN, Osrow RA, Franke MF, Iyamuremye JD,  et al.
2017-02-01 • BMJ Open
2017-02-01 • BMJ Open
Integrating mental healthcare into primary care can reduce the global burden of mental disorders. Yet data on the effective implementation of real-world task-shared mental health program...

Cost-effectiveness of new MDR-TB regimens: study protocol for the TB-PRACTECAL economic evaluation substudy

Sweeney S, Gomez G, Kitson N, Sinha A, Yatskevich N,  et al.
2020-10-10 • BMJ Open
2020-10-10 • BMJ Open
INTRODUCTION
Current treatment regimens for multidrug-resistant tuberculosis (MDR-TB) are long, poorly tolerated and have poor outcomes. Furthermore, the costs of treating MDR-TB are...

Seasonal variations in tuberculosis diagnosis among HIV-positive individuals in Southern Africa: analysis of cohort studies at antiretroviral treatment programmes

Ballif M, Zurcher K, Reid SE, Boulle AM, Fox MP,  et al.
2018-01-11 • BMJ Open
2018-01-11 • BMJ Open
Seasonal variations in tuberculosis diagnoses have been attributed to seasonal climatic changes and indoor crowding during colder winter months. We investigated trends in pulmonary tuber...

Health conditions of migrants, refugees and asylum seekers on search and rescue vessels on the central Mediterranean Sea, 2016-2019: a retrospective analysis

Van Boetzelaer E, Fotso A, Angelova I, Huisman G, Thorson T,  et al.
2022-01-11 • BMJ Open
2022-01-11 • BMJ Open
OBJECTIVES
This study will contribute to the systematic epidemiological description of morbidities among migrants, refugees and asylum seekers when crossing the Mediterranean Sea.

'Only twice a year': a qualitative exploration of 6-month antiretroviral treatment refills in adherence clubs for people living with HIV in Khayelitsha, South Africa

Keene CM, Zokufa N, Venables E, Wilkinson LS, Hoffman R,  et al.
2020-07-08 • BMJ Open
2020-07-08 • BMJ Open
OBJECTIVE
Longer intervals between routine clinic visits and medication refills are part of patient-centred, differentiated service delivery (DSD). They have been shown to improve pa...

Management of diabetes and associated costs in a complex humanitarian setting in the Democratic Republic of Congo: a retrospective cohort study

Ansbro É, Biringanine M, Caleo GNC, Prieto-Merino D, Sadique Z,  et al.
2019-11-24 • BMJ Open
2019-11-24 • BMJ Open
ObjectiveWe aimed to evaluate an Integrated Diabetic Clinic within a Hospital Outpatient Department (IDC-OPD) in a complex humanitarian setting...

Lived experiences of palliative care among people living with HIV/AIDS: a qualitative study from Bihar, India

Nair MM, Kumar P, Mahajan R, Harshana A, Richardson K,  et al.
2020-10-05 • BMJ Open
2020-10-05 • BMJ Open
OBJECTIVES
This study aimed to assess the lived experiences of palliative care among critically unwell people living with HIV/AIDS (PLHA), caregivers and relatives of deceased patien...

Missed opportunities for vaccination (MOV) in children up to 5 years old in 19 Médecins Sans Frontières-supported health facilities: a cross-sectional survey in six low-resource countries

Borras-Bermejo B, Panunzi I, Bachy C, Gil-Cuesta J
2022-07-26 • BMJ Open
2022-07-26 • BMJ Open
OBJECTIVE
To describe missed opportunities for vaccination (MOV) among children visiting Médecins Sans Frontières (MSF)-supported facilities, their related factors, and to identify r...

Exploring global and country-level barriers to an effective supply of leishmaniasis medicines and diagnostics in eastern Africa: a qualitative study

Sunyoto T, Potet J, den Boer ML, Ritmeijer KKD, Postigo JAR,  et al.
2019-05-01 • BMJ Open
2019-05-01 • BMJ Open
OBJECTIVES:
To understand stakeholders' perceptions of the access barriers to quality-assured diagnostics and medicines for leishmaniasis in the high-burden region of eastern Africa...

Capturing patient-reported and quality of life outcomes with use of shorter regimens for drug-resistant tuberculosis: mixed-methods substudy protocol, TB PRACTECAL-PRO

Stringer B, Lowton K, James N, Nyang'wa BT
2021-09-06 • BMJ Open
2021-09-06 • BMJ Open
INTRODUCTION
People living with multidrug-resistant tuberculosis currently have few options for effective treatment and cure. Regimens that are available are toxic, may involve injec...

Effectiveness of case-area targeted interventions including vaccination on the control of epidemic cholera: protocol for a prospective observational study

Ratnayake R, Peyraud N, Ciglenecki I, Gignoux EM, Lightowler M,  et al.
2022-07-06 • BMJ Open
2022-07-06 • BMJ Open
INTRODUCTION
Cholera outbreaks in fragile settings are prone to rapid expansion. Case-area targeted interventions (CATIs) have been proposed as a rapid and efficient response strateg...