Search Results | MSF Science Portal

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Pre-Print

Bulti AB, Dumicho AY, Shigayeva A, van Cutsem G, Steele SJ, et al.

2024-03-08 • Scientific Reports

BACKGROUND
Tuberculosis (TB) among hospitalized patients is underdiagnosed. This study assessed systematic TB-screening, followed by an enhanced TB-diagnostic package for hospitaliz...

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Research

Boulle A, van Cutsem G, Cohen K, Hilderbrand K, Mathee S, et al.

2008-08-06 • JAMA

CONTEXT
Rifampicin-based antitubercular therapy reduces the plasma concentrations of nevirapine and efavirenz. The virological consequences of these interactions are not well describ...

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Review

Stinson K, Goemaere E, Coetzee D, van Cutsem G, Hilderbrand K, et al.

2016-05-20 • International Journal of Epidemiology

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Research

Govender NP, Meintjes GA, Mangena PM, Nel J, Potgieter S, et al.

2019-11-08 • Southern African Journal of HIV medicine

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Research

Cornell M, Grimsrud A, Fairall L, Fox MP, van Cutsem G, et al.

2010-09-10 • AIDS

OBJECTIVE: Little is known about the temporal impact of the rapid scale-up of large antiretroviral therapy (ART) services on programme outcomes. We describe patient outcomes [mortality, ...

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Research

Cornell M, Technau KG, Fairall L, Wood R, Moultrie H, et al.

2009-09-01 • South African Medical Journal

OBJECTIVES: To introduce the combined South African cohorts of the International epidemiologic Databases to Evaluate AIDS Southern Africa (IeDEA-SA) collaboration as reflecting the South...

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Short Report

Nelson AM, Maritz J, Giddy J, Frigati L, Rabie H, et al.

2015-04-28 • Southern African Journal of HIV medicine

Journal Article

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Research

Chu KM, Boulle AM, Ford NP, Goemaere E, Asselman V, et al.

2010-02-17 • PLOS One

BACKGROUND: The majority of antiretroviral treatment programmes in sub-Saharan Africa are scaling up antiretroviral treatment using a fixed dose first-line antiretroviral regimen contain...

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Research

Trollip AP, Albert H, Mole R, Marshall T, van Cutsem G, et al.

2009-06-01 • International Journal of Tuberculosis and Lung Disease

Modifications in the FASTPlaqueTB test protocol have resulted in an increase in the analytical limits of detection. This study investigated whether the performance of a modified prototyp...

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Research

Rangaka MX, Wilkinson KA, Seldon R, van Cutsem G, Meintjes GA, et al.

2007-12-07 • American Journal of Respiratory and Critical Care Medicine

RATIONALE: Two forms of the IFN-gamma release assay (IFNGRA) to detect tuberculosis infection are available, but neither has been evaluated in comparable HIV-infected and uninfected pers...

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Research

Rangaka MX, Wilkinson RJ, Boulle AM, Glynn JR, Fielding K, et al.

2014-05-14 • Lancet

Antiretroviral therapy reduces the risk of tuberculosis, but tuberculosis is more common in people with HIV than in people without HIV. We aimed to assess the effect of isoniazid prevent...

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Research

Rick F, Niyibizi AA, Shroufi A, Onami K, Steele SJ, et al.

2017-09-06 • PLOS One

Cryptococcal meningitis is one of the leading causes of death among people with HIV in Africa, primarily due to delayed presentation, poor availability and high cost of treatment. Routin...

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Research

Cox HS, Hughes J, Daniels J, Azevedo VD, McDermid C, et al.

2014-04-01 • International Journal of Tuberculosis and Lung Disease

SETTING: Khayelitsha, South Africa, a peri-urban township with high burdens of tuberculosis (TB), drug-resistant tuberculosis (DR-TB), and human immunodeficiency virus (HIV) infection.

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Research

Daniels J, Khogali MA, Mohr E, Cox V, Moyo S, et al.

2015-11-10 • PLOS One

SETTING
Khayelitsha, South Africa, with high burdens of rifampicin-resistant tuberculosis (RR-TB) and HIV co-infection.

OBJECTIVE
To describe time to antiretroviral trea...

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Research

Shroufi A, van Cutsem G, Cambiano V, Bansi-Matharu L, Duncan K, et al.

2019-08-01 • AIDS

BACKGROUND
Many individuals failing first-line antiretroviral therapy (ART) in sub-Saharan Africa never initiate second-line ART or do so after significant delay. For people on ART w...

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Research

Sumbi EM, Venables E, Harrison RE, Garcia MG, Iakovidi K, et al.

2021-02-03 • BMC Public Health

Background: It is estimated that 64,000 children under 15 years of age are living with HIV in the Democratic Republic of Congo (DRC). Non-disclosure - in which the child is not informed ...

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Research

Fenner L, Brinkhof MW, Keiser O, Weigel R, Cornell M, et al.

2010-08-01 • Journal of Acquired Immune Deficiency Syndromes (1999)

BACKGROUND: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in chi...

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Research

Moudachirou R, van Cutsem G, Chuy RI, Tweya H, Senkoro M, et al.

2020-03-21 • Public Health Action

Setting: In 2010, Médecins Sans Frontières set up decentralised community antiretroviral therapy (ART) refill centres ("poste de distribution communautaire", PODI) for the follow-up of s...

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Letter

Cox HS, van Cutsem G, Cox V

2014-08-01 • Lancet

Journal Article

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Research

Boulle AM, van Cutsem G, Hilderbrand K, Cragg C, Abrahams M, et al.

2010-02-20 • AIDS

OBJECTIVES: We report on outcomes after 7 years of a community-based antiretroviral therapy (ART) programme in Khayelitsha, South Africa, with death registry linkages to correct for mort...

Science Portal

Enhancing tuberculosis (TB) diagnosis among hospitalized patients in KwaZulu-Natal, South Africa: a before-and-after study of a lay health worker-driven intervention

Outcomes of nevirapine- and efavirenz-based antiretroviral therapy when coadministered with rifampicin-based antitubercular therapy

Cohort profile: the Khayelitsha antiretroviral programme, Cape Town, South Africa

Southern african HIV clinicians society guideline for the prevention, diagnosis and management of cryptococcal disease among HIV-infected persons: 2019 update

Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007

Monitoring the South African National Antiretroviral Treatment Programme, 2003-2007: the IeDEA Southern Africa collaboration

HIV testing and antiretroviral therapy initiation at birth: Views from a primary care setting in Khayelitsha

Nevirapine-associated early hepatotoxicity: incidence, risk factors, and associated mortality in a primary care ART programme in South Africa

Performance of FASTPlaqueTB and a modified protocol in a high HIV prevalence community in South Africa

Effect of HIV-1 infection on T-Cell-based and skin test detection of tuberculosis infection

Isoniazid plus antiretroviral therapy to prevent tuberculosis: a randomised double-blind, placebo-controlled trial

Cryptococcal antigen screening by lay cadres using a rapid test at the point of care: A feasibility study in rural Lesotho

Community-based treatment of drug-resistant tuberculosis in Khayelitsha, South Africa

Time to ART initiation among patients treated for rifampin-resistant tuberculosis in Khayelitsha, South Africa: Impact on mortality and treatment success

Simplifying switch to second-line antiretroviral therapy in sub Saharan Africa: predicted effect of using a single viral load to define efavirenz-based first-line failure

"It's a secret between us": a qualitative study on children and care-giver experiences of HIV disclosure in Kinshasa, Democratic Republic of Congo

Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa

Retention and sustained viral suppression in HIV patients transferred to community refill centres in Kinshasa, DRC

Better treatment of XDR tuberculosis needed in South Africa

Seven-year experience of a primary care antiretroviral treatment programme in Khayelitsha, South Africa