Search Results | MSF Science Portal

Journal Article

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Research

Nesbitt RC, Kinya Asilaza V, Alvarez C, Gitahi P, Nkemenang P, et al.

2025-01-08 • Lancet Infectious Diseases

BACKGROUND

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis, particularly in Asia and Africa, where HEV genotypes 1 and 2 are prevalen...

Journal Article

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Research

Nesbitt RC, Azman AS, Asilaza VK, Edwards JK, Gitahi P, et al.

2024-11-01 • Lancet Global Health

Conference Material

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Slide Presentation

Nesbitt R, Azman AS, Asilaza VK, Edwards JK, Nkemenang P, et al.

2024-05-16 • MSF Scientific Day International 2024

Conference Material

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Abstract

Nesbitt R, Azman AS, Asilaza VK, Edwards JK, Nkemenang P, et al.

2024-05-16 • MSF Scientific Day International 2024

INTRODUCTION

Hepatitis E causes high mortality among pregnant women, with case fatality risks over 30% and adverse fetal outcomes. There is an evidence gap on the safety of the ...

Journal Article

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Research

Nesbitt RC, Asilaza VK, Gignoux EM, Koyuncu A, Gitahi P, et al.

2024-01-22 • PLOS Neglected Tropical Diseases

INTRODUCTION

Hepatitis E (HEV) genotypes 1 and 2 are the common cause of jaundice and acute viral hepatitis that can cause large-scale outbreaks. HEV infection...

Conference Material

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Abstract

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P, et al.

2023-06-07 • MSF Scientific Day International 2023

INTRODUCTION
A three-dose recombinant vaccine against hepatitis E, Hecolin, has been licensed for use in China since 2011. While not recommended for routine use due to lack of eviden...

Conference Material

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Poster

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P, et al.

2023-06-07 • MSF Scientific Day International 2023

Conference Material

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Slide Presentation

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P, et al.

2023-06-07 • MSF Scientific Day International 2023

Journal Article

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Research

Zheng Q, Luquero FJ, Ciglenecki I, Wamala JF, Abubakar A, et al.

2022-09-01 • International Journal of Infectious Diseases

BACKGROUND
Cholera remains a public health threat but is inequitably distributed across sub-Saharan Africa. Lack of standardized reporting and inconsistent outbreak definitions limit...

Journal Article

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Letter

Ciglenecki I, Rumunu J, Wamala JF, Nkemenang P, Duncker J, et al.

2022-08-01 • Lancet Infectious Diseases

Journal Article

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Research

Jones FK, Wamala JF, Rumunu J, Mawien PN, Kol MT, et al.

2020-12-01 • Lancet Planetary health

Background
Between 2014 and 2017, successive cholera epidemics occurred in South Sudan within the context of civil war, population displacement, flooding, and drought. We aim to des...

Journal Article

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Commentary

Azman AS, Ciglenecki I, Wamala JF, Lynch JA, Aggarwal R, et al.

2019-07-25 • PLOS Neglected Tropical Diseases

Journal Article

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Research

Bliss JR, Bouhenia M, Hale P, Couturier BA, Iyer AS, et al.

2017-12-04 • American Journal of Tropical Medicine and Hygiene

Displaced persons living in camps are at an increased risk of diarrheal diseases. Subclinical carriage of pathogens may contribute to the spread of disease, especially for microbes that ...

Journal Article

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Research

Azman AS, Parker LA, Rumunu J, Tadesse F, Grandesso F, et al.

2016-11-01 • Lancet Global Health

BACKGROUND
Oral cholera vaccines represent a new effective tool to fight cholera and are licensed as two-dose regimens with 2-4 weeks between doses. Evidence from previous studies su...

Journal Article

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Commentary

Polonsky JA, Wamala JF, De Clerck H, Van Herp M, Sprecher A, et al.

2014-02-10 • American Journal of Tropical Medicine and Hygiene

Outbreaks of Ebola and Marburg virus diseases have recently increased in frequency in Uganda. This increase is probably caused by a combination of improved surveillance and laboratory ca...

Journal Article

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Research

Parker LA, Rumunu J, Jamet C, Kenyi Y, Lino RL, et al.

2017-06-08 • PLOS Neglected Tropical Diseases

INTRODUCTION
In June 2015, a cholera outbreak was declared in Juba, South Sudan. In addition to standard outbreak control measures, oral cholera vaccine (OCV) was proposed. As suffic...

Journal Article

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Research

Roddy P, Howard N, Van Kerkhove MD, Lutwama J, Wamala JF, et al.

2012-12-28 • PLOS One

A confirmed Ebola haemorrhagic fever (EHF) outbreak in Bundibugyo, Uganda, November 2007-February 2008, was caused by a putative new species (Bundibugyo ebolavirus). It included 93 putat...

Journal Article

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Research

Adjemian J, Farnon EC, Tschioko F, Wamala JF, Byaruhanga E, et al.

2011-11-01 • Journal of Infectious Diseases

Marburg hemorrhagic fever was detected among 4 miners in Ibanda District, Uganda, from June through September, 2007. Infection was likely acquired through exposure to bats or bat secreti...

Journal Article

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Research

Azman AS, Bouhenia M, Iyer AS, Rumunu J, Laku R, et al.

2017-06-07 • American Journal of Tropical Medicine and Hygiene

Large protracted outbreaks of hepatitis E virus (HEV) have been documented in displaced populations in Africa over the past decade though data are limited outside these exceptional se...

Journal Article

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Research

Ontweka L, Deng LO, Rauzier J, Debes AK, Tadesse F, et al.

2016-12-19 • PLOS One

Cholera rapid diagnostic tests (RDT) could play a central role in outbreak detection and surveillance in low-resource settings, but their modest performance has hindered their broad adop...

Science Portal

The effectiveness of two doses of recombinant hepatitis E vaccine in response to an outbreak in Bentiu, South Sudan: a case–control and bias indicator study

Safety of hepatitis E vaccine in pregnancy: an emulated target trial following a mass reactive vaccination campaign in Bentiu internally displaced persons camp, South Sudan

Safety of hepatitis E vaccine in pregnancy: emulating a target trial following a mass reactive vaccination campaign in South Sudan

Safety of hepatitis E vaccine in pregnancy: emulating a target trial following a mass reactive vaccination campaign in South Sudan

Vaccination coverage and adverse events following a reactive vaccination campaign against hepatitis E in Bentiu displaced persons camp, South Sudan

Two-dose vaccine effectiveness following the first reactive mass vaccination campaign against hepatitis E in Bentiu, South Sudan

Vaccination coverage and adverse events following immunisation after the first reactive mass vaccination campaign against Hepatitis E in Bentiu, South Sudan

Two-dose vaccine effectiveness following the first reactive mass vaccination campaign against Hepatitis E in Bentiu, South Sudan

Cholera outbreaks in sub-Saharan Africa during 2010-2019: a descriptive analysis

The first reactive vaccination campaign against hepatitis E

Successive epidemic waves of cholera in South Sudan between 2014 and 2017: a descriptive epidemiological study

Hepatitis E should be considered a neglected tropical disease

High Prevalence of Shigella or Enteroinvasive Escherichia coli Carriage among Residents of an Internally Displaced Persons Camp in South Sudan

Effectiveness of one dose of oral cholera vaccine in response to an outbreak: a case-cohort study

Emerging Filoviral Disease in Uganda: Proposed Explanations and Research Directions

Neighborhood-targeted and case-triggered use of a single dose of oral cholera vaccine in an urban setting: feasibility and vaccine coverage

Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008

Outbreak of Marburg hemorrhagic fever among miners in Kamwenge and Ibanda Districts, Uganda, 2007

High hepatitis E seroprevalence among displaced persons in South Sudan

Cholera Rapid Test with Enrichment Step Has Diagnostic Performance Equivalent to Culture