Search Results | MSF Science Portal

Journal Article

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Research

van Griensven J, van Henten S, Kibret A, Kassa M, Beyene H, et al.

2024-12-01 • EBioMedicine

BACKGROUND

Tar...

Journal Article

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Research

de Vrij N, Vandoren R, Ramadan K, Van Hul A, Ceulemans A, et al.

2024-09-30 • PLOS Neglected Tropical Diseases

Human immunodeficiency virus (HIV) co-infection is a major challenge for visceral leishmaniasis (VL) control, particularly in Ethiopia where the incidence of both pathogens is high. V...

Journal Article

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Research

van Griensven J, van Henten S, Kibret A, Kassa M, Beyene H, et al.

2024-07-19 • Clinical Infectious Diseases

Background

People with human immunodeficiency virus (PWH) with recurrent visceral leishmaniasis (VL) could potentially drive Leishmania transmission in areas wi...

Journal Article

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Research

de Vrij N, Pollmann J, Rezende AM, Ibarra-Meneses AV, Pham TT, et al.

2024-05-03 • Communications Biology

A large proportion of HIV-coinfected visceral leishmaniasis (VL-HIV) patients exhibit chronic disease with frequent VL recurrence. However, knowledge on immunological determinants underl...

Journal Article

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Pre-Print

de Vrij N, Vandoren R, Ramadan K, Van Hul A, Kassa M, et al.

2024-02-18 • medRxiv

Human immunodeficiency virus (HIV) co-infection is a major challenge for visceral leishmaniasis (VL) control, particularly in Ethiopia where the incidence of both pathogens is high. VL-H...

Journal Article

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Case Report/Series

van Griensven J, van Henten S, Kibret A, Kassa M, Beyene H, et al.

2024-01-09 • Clinical Infectious Diseases

BACKGROUND
HIV patients with recurrent visceral leishmaniasis (VL) could potentially drive Leishmania transmission in areas with anthroponotic transmission such as East-Africa, but s...

Journal Article

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Research

Van Bortel W, Mariën J, Jacobs BKM, Sinzinkayo D, Sinarinzi P, et al.

2022-12-01 • BMJ Global Health

BACKGROUND
Long-lasting insecticidal nets (LLINs) are one of the key interventions in the global fight against malaria. Since 2014, mass distribution campaigns of LLINs aim for unive...

Journal Article

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Research

Fitzpatrick G, Vogt F, Gbabai O, Black B, Santantonio M, et al.

2014-10-09 • Eurosurveillance

Case management centres (CMCs) are part of the outbreak control plan for Ebola virus disease (EVD). A CMC in Sierra Leone had 33% (138/419) of primary admissions discharged as EVD negati...

Journal Article

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Research

Abongomera C, Ritmeijer KKD, Vogt F, Buyze J, Mekonnen Z, et al.

2017-06-05 • PLOS One

BACKGROUND
In Ethiopia, case fatality rates among subgroups of visceral leishmaniasis (VL) patients are high. A clinical prognostic score for death in VL patients could contribute to...

Journal Article

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Research

Poliquin PG, Vogt F, Kasztura M, Leung A, Deschambault Y, et al.

2016-06-30 • Journal of Infectious Diseases

BACKGROUND
Ebola viruses (EBOVs) are primarily transmitted by contact with infected body fluids. Ebola treatment centers (ETCs) contain areas that are exposed to body fluids through ...

Journal Article

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Research

Fitzpatrick G, Vogt F, Gbabai O, Decroo T, Keane M, et al.

2015-05-22 • Journal of Infectious Diseases

This paper describes patient characteristics, including Ebola viral load, associated with mortality in an MSF Ebola case management centre. Out of 780 admissions between June and October...

Journal Article

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Research

Vogt F, Tayler-Smith K, Bernasconi A, Makondo E, Taziwa F, et al.

2015-06-17 • PLOS One

CD4 cell count measurement remains an important diagnostic tool for HIV care in developing countries. Insufficient laboratory capacity in rural Sub-Saharan Africa is frequently mentioned...

Journal Article

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Research

Vogt F, Van der Bergh R, Bernasconi A, Moyo B, Havazvidi L, et al.

2015-08-21 • PLOS One

Blood collected in conventional EDTA tubes requires laboratory analysis within 48 hours to provide valid CD4 cell count results. This restricts access to HIV care for patients from rural...

Protocol

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Research Protocol

Shah T, Greig J, van der Plas LM, Achar J, Caleo GNC, et al.

2016-07-01

Background

Médecins Sans Frontières (MSF) opened Ebola management centres (EMCs) in Sierra Leone in Kailahun in June, 2014, and Bo in September, 2014. Case fatality in the wes...

Journal Article

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Commentary

Addisu A, Adriaensen W, Balew A, Asfaw M, Diro EGJ, et al.

2019-02-08 • BMJ Global Health

SUMMARY BOX

The international community has pledged through the Sustainable Development Goals to eliminate neglected tropical diseases by 2030.

Authors from 19 institut...

Conference Material

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Slide Presentation

Leclair C, Marien J, Sinzinkayo D, Abdelrahman A, Lampaert E, et al.

2021-05-19 • MSF Scientific Days International 2021: Research

Journal Article

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Research

van Griensven J, Mangesha B, Mekonnen T, Fikre H, Takele Y, et al.

2018-03-29 • Frontiers in Cellular and Infection Microbiology

BACKGROUND
Biomarkers predicting the risk of VL treatment failure and relapse in VL/HIV coinfected patients are needed. Nested within a two-site clinical trial in Ethiopia (2011-2015...

Journal Article

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Research

Abongomera C, Diro EGJ, Vogt F, Tsoumanis A, Mekonnen Z, et al.

2017-10-30 • Clinical Infectious Diseases

BACKGROUND
East Africa, where Leishmania donovani is prevalent, faces the highest burden world-wide of visceral leishmaniasis (VL) and human immunodeficiency virus (HIV) coinfection...

Conference Material

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Abstract

Leclair C, Marien J, Sinzinkayo D, Abdelrahman A, Lampaert E, et al.

2021-05-19 • MSF Scientific Days International 2021: Research

INTRODUCTION
In Burundi, malaria continues to be a major public health issue as the leading cause of health facility attendance, high levels of mortality and devastating malaria epid...

Journal Article

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Research

Vogt F, Fitzpatrick G, Patten GE, Van der Bergh R, Stinson K, et al.

2015-12-17 • Eurosurveillance

Prevention of nosocomial Ebola virus (EBOV) infection among patients admitted to an Ebola management centre (EMC) is paramount. Current Médecins Sans Frontières (MSF) guidelines recommen...

Science Portal

Prediction of visceral leishmaniasis development in a highly exposed HIV cohort in Ethiopia based on Leishmania infection markers: results from the PreLeisH study

A preliminary indication that HLA-A*03:01 may be associated with visceral leishmaniasis development in people living with HIV in Ethiopia

Chronic high-level parasitemia in HIV-infected individuals with or without visceral leishmaniasis in an endemic area in Northwest Ethiopia: Potential superspreaders?

Persistent T cell unresponsiveness associated with chronic visceral leishmaniasis in HIV-coinfected patients

HLA-A*03:01 is associated with visceral leishmaniasis development in people living with HIV in Ethiopia

Chronic high level parasitemia in HIV-infected individuals with or without visceral leishmaniasis in an endemic area in North-West Ethiopia: potential superspreaders?

Long-lasting insecticidal nets provide protection against malaria for only a single year in Burundi, an African highland setting with marked malaria seasonality

Describing readmissions to an ebola case management centre (CMC), Sierra Leone, 2014

Development and external validation of a clinical prognostic score for death in visceral leishmaniasis patients in a high HIV co-infection burden area in Ethiopia

Environmental contamination and persistence of Ebola virus RNA in an Ebola treatment center

The contribution of Ebola viral load at admission and other patient characteristics to mortality in a Médecins Sans Frontières (MSF) Ebola Case Management Centre (CMC), Kailahun, Sierra Leone, June -October, 2014

Access to CD4 Testing for Rural HIV Patients: Findings from a Cohort Study in Zimbabwe

Using BD Vacutainer CD4 Stabilization Tubes for Absolute Cluster of Differentiation Type 4 Cell Count Measurement on BD FacsCount and Partec Cyflow Cytometers: A Method Comparison Study from Zimbabwe

Research Protocol - Inpatient signs and symptoms and factors associated with death in children aged 5 years and younger admitted to two Ebola management centres in Sierra Leone, 2014: a retrospective cohort study

Neglected tropical diseases and the sustainable development goals: an urgent call for action from the front line

Revision of the epidemiological situation of malaria in Burundi and the potential implications for future control

Leishmania antigenuria to predict initial treatment failure and relapse in visceral leishmaniasis/HIV coinfected patients: an exploratory study nested within a clinical trial in Ethiopia

The risk and predictors of visceral leishmaniasis relapse in HIV co-infected patients in Ethiopia: a retrospective cohort study

Revision of the epidemiological situation of malaria in Burundi and the potential implications for future control

Assessment of the MSF Triage System, Separating Patients into Different Wards Pending Ebola Virus Laboratory Confirmation, Kailahun, Sierra Leone, July to September 2014