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Review

Protection from killed whole-cell cholera vaccines: a systematic review and meta-analysis

Xu H, Tiffany A, Luquero FJ, Kanungo S, Bwire G,  et al.
2025-07-13 • Lancet Global Health
2025-07-13 • Lancet Global Health

BACKGROUND

Killed whole-cell oral cholera vaccines (kOCVs) are a standard prevention and control measure in cholera-endemic areas and during outbreaks and human...

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Review

Community-based surveillance to monitor mortality in a malaria-endemic and Ebola-epidemic setting in rural Guinea

Tiffany A, Moundekeno FP, Traore A, Haile M, Sterk E,  et al.
2016-10-03 • American Journal of Tropical Medicine and Hygiene
2016-10-03 • American Journal of Tropical Medicine and Hygiene
Multiple community-based approaches can aid in quantifying mortality in the absence of reliable health facility data. Community-based sentinel site surveillance that was used to document...

Effect of artesunate-amodiaquine on mortality related to Ebola virus disease

Gignoux EM, Azman AS, de Smet M, Azuma P, Massaquoi M,  et al.
2016-01-07 • New England Journal of Medicine
2016-01-07 • New England Journal of Medicine
BACKGROUND
Malaria treatment is recommended for patients with suspected Ebola virus disease (EVD) in West Africa, whether systematically or based on confirmed malaria diagnosis. At t...

Unreported cases in the 2014-2016 Ebola epidemic: Spatiotemporal variation, and implications for estimating transmission

Dalziel BD, Lau MSY, Tiffany A, McClelland A, Zelner J,  et al.
2018-01-22 • PLOS Neglected Tropical Diseases
2018-01-22 • PLOS Neglected Tropical Diseases
In the recent 2014-2016 Ebola epidemic in West Africa, non-hospitalized cases were an important component of the chain of transmission. However, non-hospitalized cases are at increased r...

Encouraging impact following 2.5 years of reinforced malaria control interventions in a hyperendemic region of the Republic of Guinea

Tiffany A, Moundekeno FP, Traore A, Haile M, Sterk E,  et al.
2016-05-28 • Malaria Journal
2016-05-28 • Malaria Journal
BACKGROUND
Malaria is one of the principal causes of morbidity and mortality in the Republic of Guinea, particularly in the highly endemic regions. To assist in malaria control effor...

Temporal Changes in Ebola Transmission in Sierra Leone and Implications for Control Requirements: a Real-time Modelling Study

Camacho A, Kucharski AJ, Aki-Sawyerr Y, White M, Flasche S,  et al.
2015-02-10 • PLoS Currents
2015-02-10 • PLoS Currents
Between August and November 2014, the incidence of Ebola virus disease (EVD) rose dramatically in several districts of Sierra Leone. As a result, the number of cases exceeded the capacit...

Spatial and Temporal Dynamics of Superspreading Events in the 2014-2015 West Africa Ebola Epidemic

Lau MSY, Dalziel BD, Funk S, McClelland A, Tiffany A,  et al.
2017-02-13 • Proceedings of the National Academy of Sciences
2017-02-13 • Proceedings of the National Academy of Sciences
The unprecedented scale of the Ebola outbreak in Western Africa (2014-2015) has prompted an explosion of efforts to understand the transmission dynamics of the virus and to analyze the p...

Mortality, Morbidity and Health-Seeking Behaviour during the Ebola Epidemic 2014-2015 in Monrovia Results from a Mobile Phone Survey

Kuehne A, Lynch E, Marshall E, Tiffany A, Alley I,  et al.
2016-08-23 • PLOS Neglected Tropical Diseases
2016-08-23 • PLOS Neglected Tropical Diseases
Between March 2014 and July 2015 at least 10,500 Ebola cases including more than 4,800 deaths occurred in Liberia, the majority in Monrovia. However, official numbers may have underestim...

Out of (West) Africa-Who Lost in the End?

Olliaro PL, Lasry E, Tiffany A
2014-12-15 • American Journal of Tropical Medicine and Hygiene
2014-12-15 • American Journal of Tropical Medicine and Hygiene
On October 29, 2014, 4 days before the annual meeting of the American Society of Tropical Medicine and Hygiene (ASTMH) to be held in New Orleans, LA, meeting registrants received an e-ma...

Impact and lessons learned from mass drug administrations of malaria chemoprevention during the Ebola outbreak in Monrovia, Liberia, 2014

Kuehne A, Tiffany A, Lasry E, Janssens M, Besse C,  et al.
2016-08-31 • PLOS One
2016-08-31 • PLOS One
BACKGROUND
In October 2014, during the Ebola outbreak in Liberia healthcare services were limited while malaria transmission continued. Médecins Sans Frontières (MSF) implemented a m...

The impact of control strategies and behavioural changes on the elimination of ebola from Lofa County, Liberia

Funk S, Ciglenecki I, Tiffany A, Gignoux EM, Camacho A,  et al.
2017-04-10 • Philosophical Transactions of the Royal Society B: Biological Sciences
2017-04-10 • Philosophical Transactions of the Royal Society B: Biological Sciences
The Ebola epidemic in West Africa was stopped by an enormous concerted effort of local communities and national and international organizations. It is not clear, however, how much the pu...

Estimating the number of secondary Ebola cases resulting from an unsafe burial and risk factors for transmission during the West Africa Ebola epidemic

Tiffany A, Dalziel BD, Kagume Njenge H, Johnson G, Nugba Ballah R,  et al.
2017-06-22 • PLOS Neglected Tropical Diseases
2017-06-22 • PLOS Neglected Tropical Diseases
BACKGROUND
Safely burying Ebola infected individuals is acknowledged to be important for controlling Ebola epidemics and was a major component of the 2013-2016 West Africa Ebola resp...

Emergence of Zaire Ebola Virus Disease in Guinea - Preliminary Report

Baize S, Pannetier D, Oestereich L, Rieger T, Koivogui L,  et al.
2014-10-09 • New England Journal of Medicine
2014-10-09 • New England Journal of Medicine
In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. ...

Changes in Health-Seeking Behavior Did Not Result in Increased All-Cause Mortality During the Ebola Outbreak in Western Area, Sierra Leone

Vygen S, Tiffany A, Rull M, Ventura A, Wolz A,  et al.
2016-07-25 • American Journal of Tropical Medicine and Hygiene
2016-07-25 • American Journal of Tropical Medicine and Hygiene
Little is known about the residual effects of the west African Ebola virus disease (Ebola) epidemic on non-Ebola mortality and health-seeking behavior in Sierra Leone. We conducted a ret...

People-centred surveillance: a narrative review of community-based surveillance among crisis-affected populations

Ratnayake R, Tammaro M, Tiffany A, Kongelf A, Polonsky JA,  et al.
2020-10-04 • Lancet Planetary health
2020-10-04 • Lancet Planetary health
Outbreaks of disease in settings affected by crises grow rapidly due to late detection and weakened public health systems. Where surveillance is underfunctioning, community-based surveil...