Search Results | MSF Science Portal

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Research

Cornell M, Technau KG, Fairall L, Wood R, Moultrie H, et al.

2009-09-01 • South African Medical Journal

OBJECTIVES: To introduce the combined South African cohorts of the International epidemiologic Databases to Evaluate AIDS Southern Africa (IeDEA-SA) collaboration as reflecting the South...

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Research

Gsponer T, Weigel R, Davies MA, Bolton C, Moultrie H, et al.

2012-09-17 • Pediatrics

BACKGROUND
Poor growth is an indication for antiretroviral therapy (ART) and a criterion for treatment failure. We examined variability in growth response to ART in 12 programs in Ma...

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Research

Fenner L, Brinkhof MW, Keiser O, Weigel R, Cornell M, et al.

2010-08-01 • Journal of Acquired Immune Deficiency Syndromes (1999)

BACKGROUND: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in chi...

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Research

Schomaker M, Leroy V, Wolfs T, Technau KG, Renner L, et al.

2016-06-24 • International Journal of Epidemiology

Background: There is limited knowledge about the optimal timing of antiretroviral treatment initiation in older children and adolescents. Methods: A total of 20 576 antiretroviral treatm...

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Schomaker M, Davies A, Malateste K, Renner L, Sawry S, et al.

2015-10-16 • Epidemiology

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Fortuin-de Smidt M, de Waal R, Cohen K, Technau KG, Stinson K, et al.

2017-02-13 • PLOS One

There are a limited number of paediatric antiretroviral drug options. Characterising the long term safety and durability of different antiretrovirals in children is important to optimise...

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Patten GE, Bernheimer J, Fairlie L, Rabie H, Sawry S, et al.

2018-10-11 • PLOS One

BACKGROUND:
In resource-limited settings holding regimens, such as lamivudine monotherapy (LM), are used to manage HIV-positive children failing combination antiretroviral therapy (...

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Research

Salazar-Vizcaya L, Keiser O, Technau KG, Davies MA, Haas AD, et al.

2014-10-23 • AIDS

OBJECTIVES
Many paediatric antiretroviral therapy (ART) programmes in Southern Africa rely on CD4⁺ to monitor ART. We assessed the benefit of replacing CD4⁺ by viral load monitoring....

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Davies MA, Boulle AM, Technau KG, Eley B, Moultrie H, et al.

2012-09-01 • Tropical Medicine and International Health

OBJECTIVES
To determine the improvement in positive predictive value of immunological failure criteria for identifying virological failure in HIV-infected children on antiretroviral ...

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Davies MA, Moultrie H, Eley B, Rabie H, van Cutsem G, et al.

2011-03-01 • Journal of Acquired Immune Deficiency Syndromes (1999)

With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determ...

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Nyakato P, Schomaker M, Sipambo N, Technau KG, Fatti G, et al.

2021-01-21 • AIDS

Background and objectives:
Adolescents living with perinatally acquired HIV (ALPHIV) on antiretroviral therapy (ART) have been noted to have poorer adherence, retention and virolog...

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Davies MA, Keiser O, Technau KG, Eley B, Rabie H, et al.

2009-10-01 • South African Medical Journal

OBJECTIVES: To assess paediatric antiretroviral treatment (ART) outcomes and their associations from a collaborative cohort representing 20% of the South African national treatment progr...

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Davies MA, Boulle AM, Eley B, Moultrie H, Technau KG, et al.

2011-08-11 • Tropical Medicine and International Health

Objectives To determine the diagnostic accuracy of World Health Organization (WHO) 2010 and 2006 as well as United States Department of Health and Human Services (DHHS) 2008 definitions...

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Bohlius J, Maxwell N, Spoerri A, Wainwright R, Sawry S, et al.

2016-06-01 • Pediatric Infectious Disease Journal

Science Portal

Monitoring the South African National Antiretroviral Treatment Programme, 2003-2007: the IeDEA Southern Africa collaboration

Variability of growth in children starting antiretroviral treatment in Southern Africa

Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa

Optimal Timing of Antiretroviral Treatment Initiation in HIV-Positive Children and Adolescents: a Multiregional Analysis from Southern Africa, West Africa and Europe

Growth and mortality outcomes for different antiretroviral therapy initiation criteria in children aged 1-5 years: a causal modelling analysis

First-Line Antiretroviral Drug Discontinuations in Children

Lamivudine monotherapy as a holding regimen for HIV-positive children

Viral load versus CD4⁺ monitoring and 5-year outcomes of antiretroviral therapy in HIV-positive children in Southern Africa: a cohort-based modelling study

The role of targeted viral load testing in diagnosing virological failure in children on antiretroviral therapy with immunological failure

Virologic failure and second-line antiretroviral therapy in children in South Africa--the IeDEA Southern Africa collaboration

Virologic response of adolescents living with perinatally acquired HIV receiving antiretroviral therapy in the period of early adolescence (10-14 years) in South Africa

Outcomes of the South African National Antiretroviral Treatment Programme for children: the IeDEA Southern Africa collaboration

Accuracy of immunological criteria for identifying virological failure in children on antiretroviral therapy - The IeDEA Southern Africa Collaboration

Incidence of AIDS-defining and Other Cancers in HIV-positive Children in South Africa: Record Linkage Study