Showing 1 - 11 of 11 Items
Showing 1 - 11 of 11 Items
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Journal Article
|Research
2024-09-12 • PLOS Medicine
2024-09-12 • PLOS Medicine
BACKGROUND
Hydroxychloroquine (HCQ) has proved ineffective in treating patients hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its safety an...
Journal Article
|Research
2013-11-13 • CPT: Pharmacometrics and Systems Pharmacology
2013-11-13 • CPT: Pharmacometrics and Systems Pharmacology
Pregnancy alters the pharmacokinetic properties of many antimalarial compounds. The objective of this study was to evaluate the pharmacokinetic properties of lumefantrine in pregnant and...
Journal Article
|Research
2019-06-01 • Clinical Pharmacology & Therapeutics
2019-06-01 • Clinical Pharmacology & Therapeutics
Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub‐Saharan African children and may affect the pharmacology of antimalarial drugs....
Journal Article
|Research
2019-10-25 • Clinical Pharmacology & Therapeutics
2019-10-25 • Clinical Pharmacology & Therapeutics
Poor adherence to seasonal malaria chemoprevention (SMC) might affect the protective effectiveness of SMC. Here, we evaluated the population pharmacokinetic properties of amodiaquine and...
Journal Article
|Research
2021-09-09 • Malaria Journal
2021-09-09 • Malaria Journal
BACKGROUND
In many endemic areas, Plasmodium vivax malaria is predominantly a disease of young adults and children. International recommendations for radical cure recommend fixed tar...
In many endemic areas, Plasmodium vivax malaria is predominantly a disease of young adults and children. International recommendations for radical cure recommend fixed tar...
Journal Article
|Review
2018-10-29 • BMC Medicine
2018-10-29 • BMC Medicine
Despite substantial improvement in the control of malaria and decreased prevalence of malnutrition over the past two decades, both conditions remain heavy burdens that cause hundreds of ...
Journal Article
|Research
2018-06-12 • PLOS Medicine
2018-06-12 • PLOS Medicine
The fixed dose combination of artemether-lumefantrine (AL) is the most widely used treatment for uncomplicated Plasmodium falciparum malaria. Relatively lower cure rates and lumefantrine...
Journal Article
|Research
2019-07-05 • Malaria Journal
2019-07-05 • Malaria Journal
BACKGROUND
Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potenti...
Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potenti...
Conference Material
|Abstract
2020-05-20 • MSF Scientific Days International 2020: Research
2020-05-20 • MSF Scientific Days International 2020: Research
INTRODUCTION
Seasonal malaria chemoprevention (SMC) has been widely implemented by MSF in the African Sahel. It consists of monthly courses of antimalarial drugs during the high-risk...
Seasonal malaria chemoprevention (SMC) has been widely implemented by MSF in the African Sahel. It consists of monthly courses of antimalarial drugs during the high-risk...
Journal Article
|Research
2013-08-05 • Antimicrobial Agents and Chemotherapy
2013-08-05 • Antimicrobial Agents and Chemotherapy
Journal Article
|Research
2008-03-01 • Antimicrobial Agents and Chemotherapy
2008-03-01 • Antimicrobial Agents and Chemotherapy
The population pharmacokinetics of piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria treated with two different dosage regimens of dihydroartemisinin-pi...