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Showing 1 - 7 of 7 Items
Showing 1 - 7 of 7 Items
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Research

rVSV-ZEBOV vaccination in people with pre-existing immunity to Ebolavirus: an open-label safety and immunogenicity study in Guinean communities affected by Ebola virus disease (l’essai proches)

Watson CH, Gsell PS, Hall Y, Camacho A, Riveros X,  et al.
2024-11-07 • BMC Medicine
2024-11-07 • BMC Medicine

BACKGROUND

Zaire Ebolavirus disease (EVD) outbreaks can be controlled using rVSV-ZEBOV vaccination and other public health measures. People in high-risk areas m...

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Journal Article
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Research

Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa

Carroll MW, Matthews DA, Hiscox JA, Elmore MJ, Pollakis G,  et al.
2015-06-17 • Nature
2015-06-17 • Nature
West Africa is currently witnessing the most extensive Ebola virus (EBOV) outbreak so far recorded. Until now, there have been 27,013 reported cases and 11,134 deaths. The origin of the ...

Evidence for a decrease in transmission of Ebola virus — Lofa County, Liberia, June 8–November 1, 2014

Sharma A, Heijenberg N, Peter C, Bolongei J, Reeder B,  et al.
2014-11-14 • Morbidity and Mortality Weekly Report
2014-11-14 • Morbidity and Mortality Weekly Report
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?
Lofa County in Liberia has one of the highest numbers of reported cases of Ebola virus disease (Ebola) in West Africa. Government health offic...

Humoral and cellular immune response induced by rVSVΔG-ZEBOV-GP vaccine among frontline workers during the 2013-2016 West Africa Ebola outbreak in Guinea

Juan-Giner A, Hitchings MD, Soumah A, Strecker T, Sadjo M,  et al.
2020-06-01 • Vaccine
2020-06-01 • Vaccine
Background
As part of a Phase III trial with the Ebola vaccine rVSVΔG-ZEBOV-GP in Guinea, we invited frontline workers (FLWs) to participate in a sub-study to provide additional inf...

Effect of artesunate-amodiaquine on mortality related to Ebola virus disease

Gignoux EM, Azman AS, de Smet M, Azuma P, Massaquoi M,  et al.
2016-01-07 • New England Journal of Medicine
2016-01-07 • New England Journal of Medicine
BACKGROUND
Malaria treatment is recommended for patients with suspected Ebola virus disease (EVD) in West Africa, whether systematically or based on confirmed malaria diagnosis. At t...

Unique human immune signature of Ebola Virus Disease in Guinea

Ruibal P, Oestereich L, Ludtke A, Becker-Ziaja B, Wozniak DM,  et al.
2016-05-04 • Nature
2016-05-04 • Nature
Despite the magnitude of the Ebola virus disease (EVD) outbreak in West Africa, there is still a fundamental lack of knowledge about the pathophysiology of EVD. In particular, very littl...

Field evaluation of capillary blood samples as a collection specimen for the rapid diagnosis of Ebola virus infection during an outbreak emergency

Strecker T, Palyi B, Ellerbrok H, Jonckheere S, De Clerck H,  et al.
2015-05-19 • Clinical Infectious Diseases
2015-05-19 • Clinical Infectious Diseases
Reliable reverse-transcriptase polymerase chain reaction (RT-PCR)-based diagnosis of Ebola virus infection currently requires a blood sample obtained by intravenous puncture. During the ...