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Showing 1 - 8 of 8 Items
Showing 1 - 8 of 8 Items
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Research

Assessing SARS-CoV-2 transmission in African households from the reanalysis of serosurveys

Cristancho-Fajardo L, Nkuba-Ndaye A, Simons E, Hoze N, Guichet E,  et al.
2025-12-05 • American Journal of Epidemiology
2025-12-05 • American Journal of Epidemiology

Household transmission studies provided key insights on SARS-CoV-2 transmission in high-income countries but were rarely implemented in Africa. To help fill this gap, we analyzed SARS...

Journal Article
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Journal Article
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Research

Immunogenicity of an extended dose interval for the Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen in adults and children in the Democratic Republic of the Congo

Choi EM, Kasonia K, Kavunga-Membo H, Mukadi-Bamuleka D, Soumah A,  et al.
2024-07-26 • Vaccines
2024-07-26 • Vaccines

During the 2018–2020 Ebola virus disease outbreak in Democratic Republic of the Congo, a phase 3 trial of the Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine (DRC-EB-001) commenced in Goma, wit...

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

Sissoko D, Laouenan C, Folkesson E, M’Lebing A, Beavogui A,  et al.
2016-03-01 • PLOS Medicine
2016-03-01 • PLOS Medicine
Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the Ebola outbreak was at its peak, the World Health ...

Humoral and cellular immune response induced by rVSVΔG-ZEBOV-GP vaccine among frontline workers during the 2013-2016 West Africa Ebola outbreak in Guinea

Juan-Giner A, Hitchings MD, Soumah A, Strecker T, Sadjo M,  et al.
2020-06-01 • Vaccine
2020-06-01 • Vaccine
Background
As part of a Phase III trial with the Ebola vaccine rVSVΔG-ZEBOV-GP in Guinea, we invited frontline workers (FLWs) to participate in a sub-study to provide additional inf...

Factors influencing participation in an Ebola vaccine trial among frontline workers in Guinea

Grantz KH, Claudot P, Kambala M, Kouyate M, Soumah A,  et al.
2019-11-15 • Vaccine
2019-11-15 • Vaccine
BACKGROUND
Alongside the clinical aspects of the immunogenicity and safety trial of an Ebola vaccine deployed among front-line workers, a qualitative study was conducted to describe ...

Factors influencing participation in an Ebola vaccine trial among front-line workers in Guinea

Grantz KH, Claudot P, Kambala M, Kouyate M, Soumah A,  et al.
2019-11-15 • Vaccine
2019-11-15 • Vaccine
BACKGROUND
Alongside the clinical aspects of the immunogenicity and safety trial of an Ebola vaccine deployed among front-line workers, a qualitative study was conducted to describe ...

Efficacy and Effectiveness of an rVSV-Vectored Vaccine in Preventing Ebola Virus Disease: Final Results from the Guinea Ring Vaccination, Open-Label, Cluster-Randomised Trial (Ebola Ça Suffit!)

Henao-Restrepo AM, Camacho A, Longini I, Watson CH, Edmunds WJ,  et al.
2017-02-01 • Lancet
2017-02-01 • Lancet
BACKGROUND
rVSV-ZEBOV is a recombinant, replication competent vesicular stomatitis virus-based candidate vaccine expressing a surface glycoprotein of Zaire Ebolavirus. We tested the ...

Safety of the rVSV ZEBOV vaccine against Ebola Zaire among frontline workers in Guinea

Juan-Giner A, Tchaton M, Jemmy J-P, Soumah A, Faga EM,  et al.
2018-09-25 • Vaccine
2018-09-25 • Vaccine
As part of the ring vaccination trial in Guinea, Front Line Workers were invited to participate in a sub-study to provide additional information on the immunogenicity and safety of rVSVΔ...