Search Results | MSF Science Portal

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Letter

Venter WDF, Gandhi M, Sokhela S, Sikwese K, Bygrave H, et al.

2024-10-01 • Lancet HIV

Journal Article

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Research

Boyce RM, Ndizeye R, Ngelese H, Baguma E, Shem B, et al.

2023-03-27 • PLOS Global Public Health

Barriers continue to limit access to viral load (VL) monitoring across sub-Saharan Africa adversely impacting control of the HIV epidemic. The objective of this study was to determine wh...

Journal Article

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Research

Musinguzi N, Mocello AR, Boum Y II, Hunt PW, Martin JN, et al.

2016-06-02 • AIDS and Behavior

Little is known about associations between viral suppression, adherence, and duration of prior viral suppression in sub-Saharan Africa. Study participants were from the UARTO study in Mb...

Journal Article

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Research

Orikiriza P, Tibenderana B, Siedner MJ, Mueller YK, Byarugaba F, et al.

2015-02-06 • PLOS One

There are limited data on region-specific drug susceptibility of tuberculosis (TB) in Uganda. We performed resistance testing on specimens collected from treatment-naive patients with pu...

Journal Article

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Research

Castillo-Mancilla JR, Morrow M, Boum Y II, Byakwaga H, Haberer JE, et al.

2018-01-16 • Journal of Acquired Immune Deficiency Syndromes (1999)

Residual systemic inflammation persists despite suppressive antiretroviral therapy (ART) and is associated with non-AIDS clinical outcomes. We aimed to evaluate the association between A...

Journal Article

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Research

Bebell LM, Kembabazi A, Musinguzi N, Martin JN, Hunt PW, et al.

2021-12-01 • SSM - Mental Health

Depression affects over 40% of people with HIV (PHIV) in low- and middle-income countries, and over half of PHIV report HIV-related internalized stigma. However, few longitudinal studies...

Journal Article

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Research

Venkataramani AS, Thirumurthy H, Haberer JE, Boum Y II, Siedner MJ, et al.

2014-01-08 • AIDS

OBJECTIVE
To determine whether earlier initiation of antiretroviral therapy (ART) is associated with better economic outcomes.

DESIGN
Prospective cohort study of HIV-pos...

Journal Article

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Research

Boyce RM, Muhindo E, Baguma E, Muhindo R, Shem B, et al.

2022-02-23 • Malaria Journal

BACKGROUND
Progress against malaria has stalled and may even be slipping backwards in high-burden countries. This is due to a range of factors including insecticide resistance and mo...

Journal Article

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Research

Murungi M, Fulton T, Reyes R, Matte M, Ntaro M, et al.

2017-05-01 • Journal of Clinical Microbiology

Poor specificity may negatively impact rapid diagnostic test (RDT)-based diagnostic strategies for malaria. We performed real-time PCR on a subset of subjects who had undergone diagnosti...

Journal Article

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Research

Bebell LM, Ngonzi J, Bazira J, Fajardo Y, Boatin AA, et al.

2017-04-13 • PLOS One

INTRODUCTION
Puerperal sepsis causes 10% of maternal deaths in Africa, but prospective studies on incidence, microbiology and antimicrobial resistance are lacking.

METHODS

Journal Article

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Research

Kim JH, Hemphill LC, Boum Y II, Bangsberg DR, Siedner MJ

2015-03-12 • Annals of Global Health

BACKGROUND
Non-communicable diseases (NCDs) account for the majority of adult deaths worldwide, and 80% of these deaths occur in
low and middle-income countries (LMICs). The burd...

Journal Article

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Research

Musinguzi N, Castillo-Mancilla JR, Morrow M, Byakwaga H, Mawhinney S, et al.

2019-12-01 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)

BACKGROUND
Residual systemic inflammation, which is associated with non-AIDS clinical outcomes, may persist despite viral suppression. We assessed the effect of antiretroviral therap...

Journal Article

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Research

Muiru AN, Bibangambah P, Hemphill LC, Sentongo R, Kim JH, et al.

2018-04-11 • Journal of Acquired Immune Deficiency Syndromes (1999)

BACKGROUND
The utility and validity of cardiovascular diseases (CVD) risk scores are not well studied in sub-Saharan Africa. We compared and correlated CVD risk scores with carotid i...

Journal Article

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Research

Katawera V, Siedner MJ, Boum Y II

2014-10-07 • BMC Microbiology

BackgroundThe resazurin microtiter assay (classic REMA), a colorimetric liquid culture-based drug susceptibility assay for Mycobacterium tuberculosis (MTB), has been endorsed by the Worl...

Journal Article

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Research

Yang IT, Hemphill LC, Kim J-H, Bibangambah P, Sentongo R, et al.

2020-06-01 • Journal of Global Health

Background
Cardiovascular disease (CVD) morbidity and mortality are increasing in sub-Saharan Africa (sSA), highlighting the need for tools to enable CVD risk stratification in the ...

Journal Article

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Research

Bebell LM, Siedner MJ, Musinguzi N, Boum Y II, Bwana BM, et al.

2016-09-20 • International Journal of STD and AIDS

Recent ecological data demonstrate improving outcomes for HIV-infected people in sub-Saharan Africa. Recently, Uganda has experienced a resurgence in HIV incidence and prevalenc...

Journal Article

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Research

Bilounga Ndongo C, Eteki L, Siedner MJ, Mbaye R, Chen JH, et al.

2018-07-26 • Journal of Viral Hepatitis

Hepatitis B virus (HBV) infection is hyperendemic in Cameroon, and health care workers (HCWs) are at high-risk of infection. We aimed to assess prevalence, risk factors and vaccine cover...

Journal Article

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Research

Monaco CL, Gootenberg DB, Zhao G, Handley SA, Ghebremichael MS, et al.

2016-03-09 • Cell Host and Microbe

Human immunodeficiency virus (HIV) infection is associated with increased intestinal translocation of microbial products and enteropathy as well as alterations in gut bacterial communiti...

Journal Article

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Research

Omoding D, Katawera V, Siedner MJ, Boum Y II

2014-10-22 • BMC Research Notes

Point-of-care tests have the capacity to improve healthcare delivery by reducing costs and delay associated with care. A novel point-of-care immunochromatographic test for dual diagnosis...

Science Portal

The long wait for long-acting HIV prevention and treatment formulations

It takes more than a machine: A pilot feasibility study of point-of-care HIV-1 viral load testing at a lower-level health center in rural western Uganda

Duration of viral suppression and risk of rebound viremia with first-line antiretroviral therapy in rural Uganda

Low Resistance to First and Second Line Anti-Tuberculosis Drugs among Treatment Naive Pulmonary Tuberculosis Patients in Southwestern Uganda

Higher Art Adherence is Associated with Lower Systemic Inflammation in Treatment-Naïve Ugandans Who Achieve Virologic Suppression

Internalized stigma, depressive symptoms, and the modifying role of antiretroviral therapy: A cohort study in rural Uganda

CD4+ cell count at antiretroviral therapy initiation and economic restoration in rural Uganda

Permethrin-treated baby wraps for the prevention of malaria: results of a randomized controlled pilot study in rural Uganda

Improving the specificity of Plasmodium falciparum malaria diagnosis in high-transmission settings with a two-step rapid diagnostic test and microscopy algorithm

Antimicrobial-resistant infections among postpartum women at a Ugandan referral hospital

Implementation of low-cost, point-of-care cardiovascular diagnostics by non-healthcare professionals in rural Uganda

Antiretroviral therapy adherence interruptions are associated with systemic inflammation among Ugandans who achieved viral suppression

Distribution and performance of cardiovascular risk scores in a mixed population of HIV-infected and community-based HIV-uninfected individuals in Uganda

Evaluation of the modified colorimetric resazurin microtiter plate-based antibacterial assay for rapid and reliable tuberculosis drug susceptibility testing

To fast or not to fast: Lipid measurement and cardiovascular disease risk estimation in rural sub-Saharan Africa

Trends in one-year cumulative incidence of death between 2005 and 2013 among patients initiating antiretroviral therapy in Uganda

Prevalence and vaccination coverage of Hepatitis B among healthcare workers in Cameroon: A national seroprevalence survey

Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome

Evaluation of the SD BIOLINE HIV/syphilis Duo assay at a rural health center in Southwestern Uganda