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Showing 1 - 3 of 3 Items
Showing 1 - 3 of 3 Items
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Journal Article
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Commentary

Target product profile (TPP) for Chagas disease point-of-care diagnosis and assessment of response to treatment

Porras AI, Yadon ZE, Altcheh J, Britto C, Chaves GC,  et al.
2015-06-04 • PLOS Neglected Tropical Diseases
2015-06-04 • PLOS Neglected Tropical Diseases
Journal Article
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Research

Real-Time PCR for the Evaluation of Treatment Response in Clinical Trials of Adult Chronic Chagas Disease: Usefulness of Serial Blood Sampling and qPCR Replicates

Parrado R, Ramirez JC, de la Barra A, Alonso-Vega C, Juiz N,  et al.
2018-12-03 • Antimicrobial Agents and Chemotherapy
2018-12-03 • Antimicrobial Agents and Chemotherapy
This work evaluated a serial blood sampling procedure to enhance the sensitivity of duplex real-time PCR (qPCR) for baseline detection and quantification of parasitic loads and post-trea...
Journal Article
|
Research

First external Quality Assurance Program for bloodstream Real-Time PCR monitoring of treatment response in clinical trials of Chagas disease

Ramirez JC, Parrado R, Sulleiro E, de la Barra A, Rodriguez M,  et al.
2017-11-27 • PLOS One
2017-11-27 • PLOS One
Real-Time PCR (qPCR) testing is recommended as both a diagnostic and outcome measurement of etiological treatment in clinical practice and clinical trials of Chagas disease (CD), but no ...