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Showing 1 - 6 of 6 Items
Showing 1 - 6 of 6 Items
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Research

High prevalence of multidrug-resistant tuberculosis, Swaziland, 2009-2010

Sanchez-Padilla E, Dlamini T, Ascorra A, Rusch-Gerdes S, Tefera ZD,  et al.
2012-01-01 • Emerging Infectious Diseases
2012-01-01 • Emerging Infectious Diseases
In Africa, although emergence of multidrug-resistant (MDR) tuberculosis (TB) represents a serious threat in countries severely affected by the HIV epidemic, most countries lack drug-resi...
Journal Article
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Research
Journal Article
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Research
Journal Article
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Research
Journal Article
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Research
Journal Article
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Research

Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment

Feuerriegel S, Cox HS, Zarkua N, Karimovich HA, Braker K,  et al.
2009-05-26 • Antimicrobial Agents and Chemotherapy
2009-05-26 • Antimicrobial Agents and Chemotherapy
The rapid detection of Mycobacterium tuberculosis isolates resistant to second-line drugs is crucial for the institution of appropriate treatment regimens as early as possible. Although ...

Whole genome sequencing reveals complex evolution patterns of multidrug-resistant mycobacterium tuberculosis Beijing strains in patients

Merker M, Kohl TA, Roetzer A, Truebe L, Richter E,  et al.
2013-12-06 • PLOS One
2013-12-06 • PLOS One
Multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains represent a major threat for tuberculosis (TB) control. Treatment of MDR-TB patients is long and less effectiv...

Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage

Merker M, Blin C, Mona S, Duforet-Frebourg N, Lecher S,  et al.
2015-01-19 • Nature Genetics
2015-01-19 • Nature Genetics
Mycobacterium tuberculosis strains of the Beijing lineage are globally distributed and are associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia. Here w...

embCAB Sequence Variation Among Ethambutol-Resistant Mycobacterium Tuberculosis Isolates Without embB306 Mutation

Plinke C, Cox HS, Zarkua N, Karimovich HA, Braker K,  et al.
2010-07-01 • Journal of Antimicrobial Chemotherapy
2010-07-01 • Journal of Antimicrobial Chemotherapy
Mechanisms of resistance to ethambutol in Mycobacterium tuberculosis remain inadequately described. Although there is mounting evidence that mutations of codon 306 in embB play a key rol...

Treatment of tuberculosis in a region with high drug resistance: Outcomes, drug resistance amplification and re-infection

Bonnet MMB, Pardini M, Meacci F, Orru G, Yesilkaya H,  et al.
2011-08-23 • PLOS One
2011-08-23 • PLOS One
Introduction: Emerging antituberculosis drug resistance is a serious threat for tuberculosis (TB) control, especially in Eastern European countries. Methods: We combined drug susceptibil...