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Showing 1 - 20 of 23 Items
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Conference Material
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Poster

The field performance of hepatitis E diagnostics during an outbreak in Bentiu, South Sudan

Koyuncu A, Nesbitt R, Alvarez C, Asilaza KV, Wamala J,  et al.
2025-05-22 • MSF Scientific Days International 2025
2025-05-22 • MSF Scientific Days International 2025
Conference Material
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Poster

Dry blood spots as a practical alternative for confirming hepatitis E

Azman AS, Nesbitt R, Alvarez C, Asilaza KV, Wamala J,  et al.
2025-05-22 • MSF Scientific Days International 2025
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Letter

The first reactive vaccination campaign against hepatitis E

Ciglenecki I, Rumunu J, Wamala JF, Nkemenang P, Duncker J,  et al.
2022-08-01 • Lancet Infectious Diseases
Journal Article
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Commentary
Journal Article
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Letter
Journal Article
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Research
2025-05-22 • MSF Scientific Days International 2025

High confidence and demand for hepatitis E vaccine during an outbreak in Bentiu, South Sudan: A qualitative study

Koyuncu A, Asilaza KV, Rumunu J, Wamala J, Gitahi P,  et al.
2025-03-06 • PLOS Global Public Health
2025-03-06 • PLOS Global Public Health

In 2021 in response to an outbreak of hepatitis E in Bentiu internally displaced persons camp the South Sudanese Ministry of Health with support from Médecins Sans Frontières implemen...

The effectiveness of two doses of recombinant hepatitis E vaccine in response to an outbreak in Bentiu, South Sudan: a case–control and bias indicator study

Nesbitt RC, Kinya Asilaza V, Alvarez C, Gitahi P, Nkemenang P,  et al.
2025-01-08 • Lancet Infectious Diseases
2025-01-08 • Lancet Infectious Diseases

BACKGROUND

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis, particularly in Asia and Africa, where HEV genotypes 1 and 2 are prevalen...

Safety of hepatitis E vaccine in pregnancy: an emulated target trial following a mass reactive vaccination campaign in Bentiu internally displaced persons camp, South Sudan

Nesbitt RC, Azman AS, Asilaza VK, Edwards JK, Gitahi P,  et al.
2024-11-01 • Lancet Global Health
2024-11-01 • Lancet Global Health

Safety of hepatitis E vaccine in pregnancy: emulating a target trial following a mass reactive vaccination campaign in South Sudan

Nesbitt R, Azman AS, Asilaza VK, Edwards JK, Nkemenang P,  et al.
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024

Safety of hepatitis E vaccine in pregnancy: emulating a target trial following a mass reactive vaccination campaign in South Sudan

Nesbitt R, Azman AS, Asilaza VK, Edwards JK, Nkemenang P,  et al.
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024

INTRODUCTION

Hepatitis E causes high mortality among pregnant women, with case fatality risks over 30% and adverse fetal outcomes. There is an evidence gap on the safety of the ...

Vaccination coverage and adverse events following a reactive vaccination campaign against hepatitis E in Bentiu displaced persons camp, South Sudan

Nesbitt RC, Asilaza VK, Gignoux EM, Koyuncu A, Gitahi P,  et al.
2024-01-22 • PLOS Neglected Tropical Diseases
2024-01-22 • PLOS Neglected Tropical Diseases

INTRODUCTION

Hepatitis E (HEV) genotypes 1 and 2 are the common cause of jaundice and acute viral hepatitis that can cause large-scale outbreaks. HEV infection...

Two-dose vaccine effectiveness following the first reactive mass vaccination campaign against hepatitis E in Bentiu, South Sudan

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
INTRODUCTION
A three-dose recombinant vaccine against hepatitis E, Hecolin, has been licensed for use in China since 2011. While not recommended for routine use due to lack of eviden...

Vaccination coverage and adverse events following immunisation after the first reactive mass vaccination campaign against Hepatitis E in Bentiu, South Sudan

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023

Two-dose vaccine effectiveness following the first reactive mass vaccination campaign against Hepatitis E in Bentiu, South Sudan

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023

Successive epidemic waves of cholera in South Sudan between 2014 and 2017: a descriptive epidemiological study

Jones FK, Wamala JF, Rumunu J, Mawien PN, Kol MT,  et al.
2020-12-01 • Lancet Planetary health
2020-12-01 • Lancet Planetary health
Background
Between 2014 and 2017, successive cholera epidemics occurred in South Sudan within the context of civil war, population displacement, flooding, and drought. We aim to des...

Hepatitis E virus outbreak among Tigray War refugees from Ethopia, Sudan

Azman AS, Gignoux E, Nesbitt R, Rumunu J, Aggarwal R,  et al.
2023-02-01 • Emerging Infectious Diseases
2023-02-01 • Emerging Infectious Diseases

High Prevalence of Shigella or Enteroinvasive Escherichia coli Carriage among Residents of an Internally Displaced Persons Camp in South Sudan

Bliss JR, Bouhenia M, Hale P, Couturier BA, Iyer AS,  et al.
2017-12-04 • American Journal of Tropical Medicine and Hygiene
2017-12-04 • American Journal of Tropical Medicine and Hygiene
Displaced persons living in camps are at an increased risk of diarrheal diseases. Subclinical carriage of pathogens may contribute to the spread of disease, especially for microbes that ...

Effectiveness of one dose of oral cholera vaccine in response to an outbreak: a case-cohort study

Azman AS, Parker LA, Rumunu J, Tadesse F, Grandesso F,  et al.
2016-11-01 • Lancet Global Health
2016-11-01 • Lancet Global Health
BACKGROUND
Oral cholera vaccines represent a new effective tool to fight cholera and are licensed as two-dose regimens with 2-4 weeks between doses. Evidence from previous studies su...

Neighborhood-targeted and case-triggered use of a single dose of oral cholera vaccine in an urban setting: feasibility and vaccine coverage

Parker LA, Rumunu J, Jamet C, Kenyi Y, Lino RL,  et al.
2017-06-08 • PLOS Neglected Tropical Diseases
2017-06-08 • PLOS Neglected Tropical Diseases
INTRODUCTION
In June 2015, a cholera outbreak was declared in Juba, South Sudan. In addition to standard outbreak control measures, oral cholera vaccine (OCV) was proposed. As suffic...
2022-08-01 • Lancet Infectious Diseases

The first use of the global oral cholera vaccine emergency stockpile: Lessons from South Sudan

Abubakar A, Azman AS, Rumunu J, Ciglenecki I, Helderman T,  et al.
2015-11-17 • PLOS Medicine
2015-11-17 • PLOS Medicine
SUMMARY POINTS

• A global oral cholera vaccine (OCV) stockpile was established in 2013 to improve rapid access to the vaccine in outbreaks and emergencies in which cholera risk...

Vaccination against cholera in Juba - authors' reply

Ciglenecki I, Azman AS, Rumunu J, Cabrol JC, Luquero FJ
2017-05-01 • Lancet Infectious Diseases
2017-05-01 • Lancet Infectious Diseases

High hepatitis E seroprevalence among displaced persons in South Sudan

Azman AS, Bouhenia M, Iyer AS, Rumunu J, Laku R,  et al.
2017-06-07 • American Journal of Tropical Medicine and Hygiene
2017-06-07 • American Journal of Tropical Medicine and Hygiene

Large protracted outbreaks of hepatitis E virus (HEV) have been documented in displaced populations in Africa over the past decade though data are limited outside these exceptional se...