Search Results | MSF Science Portal

Journal Article

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Research

Koyuncu A, Asilaza KV, Rumunu J, Wamala J, Gitahi P, et al.

2025-03-06 • PLOS Global Public Health

In 2021 in response to an outbreak of hepatitis E in Bentiu internally displaced persons camp the South Sudanese Ministry of Health with support from Médecins Sans Frontières implemen...

Journal Article

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Research

Nesbitt RC, Kinya Asilaza V, Alvarez C, Gitahi P, Nkemenang P, et al.

2025-01-08 • Lancet Infectious Diseases

BACKGROUND

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis, particularly in Asia and Africa, where HEV genotypes 1 and 2 are prevalen...

Journal Article

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Research

Nesbitt RC, Azman AS, Asilaza VK, Edwards JK, Gitahi P, et al.

2024-11-01 • Lancet Global Health

Conference Material

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Slide Presentation

Nesbitt R, Azman AS, Asilaza VK, Edwards JK, Nkemenang P, et al.

2024-05-16 • MSF Scientific Day International 2024

Conference Material

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Abstract

Nesbitt R, Azman AS, Asilaza VK, Edwards JK, Nkemenang P, et al.

2024-05-16 • MSF Scientific Day International 2024

INTRODUCTION

Hepatitis E causes high mortality among pregnant women, with case fatality risks over 30% and adverse fetal outcomes. There is an evidence gap on the safety of the ...

Journal Article

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Research

Nesbitt RC, Asilaza VK, Gignoux EM, Koyuncu A, Gitahi P, et al.

2024-01-22 • PLOS Neglected Tropical Diseases

INTRODUCTION

Hepatitis E (HEV) genotypes 1 and 2 are the common cause of jaundice and acute viral hepatitis that can cause large-scale outbreaks. HEV infection...

Conference Material

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Abstract

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P, et al.

2023-06-07 • MSF Scientific Day International 2023

INTRODUCTION
A three-dose recombinant vaccine against hepatitis E, Hecolin, has been licensed for use in China since 2011. While not recommended for routine use due to lack of eviden...

Conference Material

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Poster

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P, et al.

2023-06-07 • MSF Scientific Day International 2023

Conference Material

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Slide Presentation

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P, et al.

2023-06-07 • MSF Scientific Day International 2023

Journal Article

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Letter

Azman AS, Gignoux E, Nesbitt R, Rumunu J, Aggarwal R, et al.

2023-02-01 • Emerging Infectious Diseases

Journal Article

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Letter

Ciglenecki I, Rumunu J, Wamala JF, Nkemenang P, Duncker J, et al.

2022-08-01 • Lancet Infectious Diseases

Journal Article

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Research

Jones FK, Wamala JF, Rumunu J, Mawien PN, Kol MT, et al.

2020-12-01 • Lancet Planetary health

Background
Between 2014 and 2017, successive cholera epidemics occurred in South Sudan within the context of civil war, population displacement, flooding, and drought. We aim to des...

Journal Article

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Research

Bliss JR, Bouhenia M, Hale P, Couturier BA, Iyer AS, et al.

2017-12-04 • American Journal of Tropical Medicine and Hygiene

Displaced persons living in camps are at an increased risk of diarrheal diseases. Subclinical carriage of pathogens may contribute to the spread of disease, especially for microbes that ...

Journal Article

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Research

Azman AS, Parker LA, Rumunu J, Tadesse F, Grandesso F, et al.

2016-11-01 • Lancet Global Health

BACKGROUND
Oral cholera vaccines represent a new effective tool to fight cholera and are licensed as two-dose regimens with 2-4 weeks between doses. Evidence from previous studies su...

Journal Article

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Research

Parker LA, Rumunu J, Jamet C, Kenyi Y, Lino RL, et al.

2017-06-08 • PLOS Neglected Tropical Diseases

INTRODUCTION
In June 2015, a cholera outbreak was declared in Juba, South Sudan. In addition to standard outbreak control measures, oral cholera vaccine (OCV) was proposed. As suffic...

Journal Article

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Commentary

Abubakar A, Azman AS, Rumunu J, Ciglenecki I, Helderman T, et al.

2015-11-17 • PLOS Medicine

SUMMARY POINTS

• A global oral cholera vaccine (OCV) stockpile was established in 2013 to improve rapid access to the vaccine in outbreaks and emergencies in which cholera risk...

Journal Article

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Letter

Ciglenecki I, Azman AS, Rumunu J, Cabrol JC, Luquero FJ

2017-05-01 • Lancet Infectious Diseases

Journal Article

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Research

Azman AS, Bouhenia M, Iyer AS, Rumunu J, Laku R, et al.

2017-06-07 • American Journal of Tropical Medicine and Hygiene

Large protracted outbreaks of hepatitis E virus (HEV) have been documented in displaced populations in Africa over the past decade though data are limited outside these exceptional se...

Journal Article

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Commentary

Abubakar A, Bwire GS, Azman AS, Bouhenia M, Deng LO, et al.

2018-05-01 • Emerging Infectious Diseases

Combining the official cholera line list data and outbreak investigation reports from the ministries of health in Uganda and South Sudan with molecular analysis of Vibrio cholerae strain...

Journal Article

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Commentary

Parker LA, Rumunu J, Jamet C, Kenyi Y, Lino RL, et al.

2017-04-01 • Lancet Infectious Diseases

Shortages of vaccines for epidemic diseases, such as cholera, meningitis, and yellow fever, have become common over the past decade, hampering efforts to control outbreaks through mass r...

Science Portal

High confidence and demand for hepatitis E vaccine during an outbreak in Bentiu, South Sudan: A qualitative study

The effectiveness of two doses of recombinant hepatitis E vaccine in response to an outbreak in Bentiu, South Sudan: a case–control and bias indicator study

Safety of hepatitis E vaccine in pregnancy: an emulated target trial following a mass reactive vaccination campaign in Bentiu internally displaced persons camp, South Sudan

Safety of hepatitis E vaccine in pregnancy: emulating a target trial following a mass reactive vaccination campaign in South Sudan

Safety of hepatitis E vaccine in pregnancy: emulating a target trial following a mass reactive vaccination campaign in South Sudan

Vaccination coverage and adverse events following a reactive vaccination campaign against hepatitis E in Bentiu displaced persons camp, South Sudan

Two-dose vaccine effectiveness following the first reactive mass vaccination campaign against hepatitis E in Bentiu, South Sudan

Vaccination coverage and adverse events following immunisation after the first reactive mass vaccination campaign against Hepatitis E in Bentiu, South Sudan

Two-dose vaccine effectiveness following the first reactive mass vaccination campaign against Hepatitis E in Bentiu, South Sudan

Hepatitis E virus outbreak among Tigray War refugees from Ethopia, Sudan

The first reactive vaccination campaign against hepatitis E

Successive epidemic waves of cholera in South Sudan between 2014 and 2017: a descriptive epidemiological study

High Prevalence of Shigella or Enteroinvasive Escherichia coli Carriage among Residents of an Internally Displaced Persons Camp in South Sudan

Effectiveness of one dose of oral cholera vaccine in response to an outbreak: a case-cohort study

Neighborhood-targeted and case-triggered use of a single dose of oral cholera vaccine in an urban setting: feasibility and vaccine coverage

The first use of the global oral cholera vaccine emergency stockpile: Lessons from South Sudan

Vaccination against cholera in Juba - authors' reply

High hepatitis E seroprevalence among displaced persons in South Sudan

Cholera epidemic in South Sudan and Uganda and need for international collaboration in cholera control

Adapting to the global shortage of cholera vaccines: targeted single dose cholera vaccine in response to an outbreak in South Sudan