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Copyright © Médecins Sans Frontières
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Showing 1 - 5 of 5 Items
Showing 1 - 5 of 5 Items
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Protocol
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Research Protocol

Survey of Plasmodium falciparum sulfadoxine/pyrimethamine (SP) resistance markers in MSF projects in North and South Kivu, DR Congo

de Wit MBK, Rao B, Lassovski M, Ouabo A, Badjo C,  et al.
2018-07-01
2018-07-01
Primary Objective: To measure the prevalence of molecular markers of SP resistant malaria in North and South Kivu, DRC.

Sulfadoxine/pyrimethamine (SP) forms the backbone of mos...
Journal Article
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Research

Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malaria

Pearce RJ, Pota H, Evehe M-SB, Ba EH, Mombo-Ngoma G,  et al.
2009-04-14 • PLOS Medicine
2009-04-14 • PLOS Medicine
BACKGROUND: Although the molecular basis of resistance to a number of common antimalarial drugs is well known, a geographic description of the emergence and dispersal of resistance mutat...
Journal Article
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Research

Markers of sulfadoxine–pyrimethamine resistance in Eastern Democratic Republic of Congo; implications for malaria chemoprevention

van Lenthe M, van der Meulen R, Lassovsky M, Ouabo A, Bakula E,  et al.
2019-12-18 • Malaria Journal
2019-12-18 • Malaria Journal
BACKGROUND
Sulfadoxine–pyrimethamine (SP) is a cornerstone of malaria chemoprophylaxis and is considered for programmes in the Democratic Republic of Congo (DRC). However, SP efficac...
Journal Article
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Research

Independent Origin of Plasmodium falciparum Antifolate Super-Resistance, Uganda, Tanzania, and Ethiopia

Alifrangis M, Nag S, Schousboe ML, Ishengoma D, Lusingu J,  et al.
2014-07-24 • Emerging Infectious Diseases
2014-07-24 • Emerging Infectious Diseases
Super-resistant Plasmodium falciparum threatens the effectiveness of sulfadoxine-pyrimethamine in intermittent preventive treatment for malaria during pregnancy. It is characterized by t...
Journal Article
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Research

Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes

Swarthout TD, van den Broek IVF, Kayembe G, Montgomery JM, Pota H,  et al.
2006-10-01 • Tropical Medicine and International Health
2006-10-01 • Tropical Medicine and International Health
We undertook a trial of artesunate + amodiaquine (AS + AQ) and artesunate + sulphadoxine-pyrimethamine (AS + SP) in 180 children of age 6-59 months with uncomplicated malaria in Democrat...