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Copyright © Médecins Sans Frontières
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Showing 1 - 5 of 5 Items
Showing 1 - 5 of 5 Items
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Journal Article
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Letter

Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa

Carroll MW, Matthews DA, Hiscox JA, Elmore MJ, Pollakis G,  et al.
2015-06-17 • Nature
2015-06-17 • Nature
West Africa is currently witnessing the most extensive Ebola virus (EBOV) outbreak so far recorded. Until now, there have been 27,013 reported cases and 11,134 deaths. The origin of the ...
Journal Article
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Research

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

Sissoko D, Laouenan C, Folkesson E, M’Lebing A, Beavogui A,  et al.
2016-03-01 • PLOS Medicine
2016-03-01 • PLOS Medicine
Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the Ebola outbreak was at its peak, the World Health ...
Journal Article
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Research

Evaluation of convalescent plasma for Ebola Virus Disease in Guinea

van Griensven J, Edwards T, de Lamballerie X, Semple MG, Gallian P,  et al.
2016-01-07 • New England Journal of Medicine
2016-01-07 • New England Journal of Medicine
BACKGROUND
In the wake of the recent outbreak of Ebola virus disease (EVD) in several African countries, the World Health Organization prioritized the evaluation of treatment with co...
Journal Article
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Research

Favipiravir Pharmacokinetics in Ebola-Infected Patients of the JIKI Trial Reveals Concentrations Lower Than Targeted

Nguyen TN, Guedj J, Anglaret X, Laouenan C, Madelain V,  et al.
2017-02-23 • PLOS Neglected Tropical Diseases
2017-02-23 • PLOS Neglected Tropical Diseases
In 2014-2015, we assessed favipiravir tolerance and efficacy in patients with Ebola virus (EBOV) disease (EVD) in Guinea (JIKI trial). Because the drug had never been used before for thi...
Journal Article
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Short Report

Emergence of Zaire Ebola Virus Disease in Guinea - Preliminary Report

Baize S, Pannetier D, Oestereich L, Rieger T, Koivogui L,  et al.
2014-10-09 • New England Journal of Medicine
2014-10-09 • New England Journal of Medicine
In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. ...