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Showing 1 - 3 of 3 Items
Showing 1 - 3 of 3 Items
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Journal Article
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Research

A Worldwide Map of Plasmodium Falciparum K13-Propeller Polymorphisms

Ménard D, Khim N, Beghain J, Adegnika AA, Alam MS,  et al.
2016-06-23 • New England Journal of Medicine
2016-06-23 • New England Journal of Medicine
Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P...
Journal Article
|
Research

A standardised phase III clinical trial framework to assess therapeutic interventions for Lassa fever

Olayinka A, Bourner J, Akpede GO, Okoeguale J, Abejegah C,  et al.
2022-01-06 • PLOS Neglected Tropical Diseases
2022-01-06 • PLOS Neglected Tropical Diseases
BACKGROUND
Only one recommendation currently exists for the treatment of Lassa fever (LF), which is ribavirin administered in conjunction with supportive care. This recommendation is...
Journal Article
|
Research

Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis

WorldWide Antimalarial Resistance Network Methodology Study Group, Dahal P, Simpson JA, Abdulla S, Achan J,  et al.
2019-07-05 • Malaria Journal
2019-07-05 • Malaria Journal
BACKGROUND
Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potenti...