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Showing 1 - 15 of 15 Items
Showing 1 - 15 of 15 Items
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Journal Article
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Research

HIV Viral Load as an Independent Risk Factor for Tuberculosis in South Africa: Collaborative Analysis of Cohort Studies

Fenner L, Atkinson A, Boulle AM, Fox MP, Prozesky HW,  et al.
2017-06-23 • Journal of the International AIDS Society
2017-06-23 • Journal of the International AIDS Society
Chronic immune activation due to ongoing HIV replication may lead to impaired immune responses against opportunistic infections such as tuberculosis (TB). We studied the role of HIV repl...
Journal Article
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Research

Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007

Cornell M, Grimsrud A, Fairall L, Fox MP, van Cutsem G,  et al.
2010-09-10 • AIDS
2010-09-10 • AIDS
OBJECTIVE: Little is known about the temporal impact of the rapid scale-up of large antiretroviral therapy (ART) services on programme outcomes. We describe patient outcomes [mortality, ...
Journal Article
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Research

Monitoring the South African National Antiretroviral Treatment Programme, 2003-2007: the IeDEA Southern Africa collaboration

Cornell M, Technau KG, Fairall L, Wood R, Moultrie H,  et al.
2009-09-01 • South African Medical Journal
2009-09-01 • South African Medical Journal
OBJECTIVES: To introduce the combined South African cohorts of the International epidemiologic Databases to Evaluate AIDS Southern Africa (IeDEA-SA) collaboration as reflecting the South...
Journal Article
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Research

Seasonal variations in tuberculosis diagnosis among HIV-positive individuals in Southern Africa: analysis of cohort studies at antiretroviral treatment programmes

Ballif M, Zurcher K, Reid SE, Boulle AM, Fox MP,  et al.
2018-01-11 • BMJ Open
2018-01-11 • BMJ Open
Seasonal variations in tuberculosis diagnoses have been attributed to seasonal climatic changes and indoor crowding during colder winter months. We investigated trends in pulmonary tuber...
Journal Article
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Research

CD4 count slope and mortality in HIV-infected patients on antiretroviral therapy: multicohort analysis from South Africa

Hoffman CJ, Schomaker M, Fox MP, Mutevedzi, Giddy J,  et al.
2013-01-22 • Journal of Acquired Immune Deficiency Syndromes (1999)
2013-01-22 • Journal of Acquired Immune Deficiency Syndromes (1999)
In many resource-limited settings monitoring of combination antiretroviral therapy (cART) is based on the current CD4 count, with limited access to HIV RNA tests or laboratory diagnostic...
Journal Article
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Research

Where do HIV-infected adolescents go after transfer? - Tracking transition/transfer of HIV-infected adolescents using linkage of cohort data to a health information system platform

Davies MA, Tsondai PR, Tiffin N, Eley B, Rabie H,  et al.
2017-03-16 • Journal of the International AIDS Society
2017-03-16 • Journal of the International AIDS Society
To evaluate long-term outcomes in HIV-infected adolescents, it is important to identify ways of tracking outcomes after transfer to a different health facility. The Department of Health ...
Journal Article
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Research

Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa

Fenner L, Brinkhof MW, Keiser O, Weigel R, Cornell M,  et al.
2010-08-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2010-08-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in chi...
Journal Article
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Research

Life expectancies of South African adults starting antiretroviral treatment: collaborative analysis of cohort studies

Johnson LF, Mossong J, Dorrington R, Schomaker M, Hoffman CJ,  et al.
2013-04-09 • PLOS Medicine
2013-04-09 • PLOS Medicine
Few estimates exist of the life expectancy of HIV-positive adults receiving antiretroviral treatment (ART) in low- and middle-income countries. We aimed to estimate the life expectancy o...
Journal Article
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Research

Risk charts to guide targeted HIV-1 viral load monitoring of ART: development and validation in patients from resource-limited settings

Koller M, Fatti G, Chi BH, Keiser O, Hoffman CJ,  et al.
2015-07-07 • Journal of Acquired Immune Deficiency Syndromes (1999)
2015-07-07 • Journal of Acquired Immune Deficiency Syndromes (1999)
Journal Article
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Research

Zidovudine impairs immunological recovery on first-line antiretroviral therapy: collaborative analysis of cohort studies in southern Africa

Wandeler G, Gsponer T, Mulenga L, Garone DB, Wood R,  et al.
2013-09-01 • AIDS
2013-09-01 • AIDS
OBJECTIVES
Zidovudine (ZDV) is recommended for first-line antiretroviral therapy (ART) in resource-limited settings. ZDV may, however, lead to anemia and impaired immunological respo...
Journal Article
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Research

Gender differences in survival among adult patients starting antiretorivral therapy in South Africa: a multicentre cohort study

Cornell M, Schomaker M, Garone DB, Giddy J, Hoffmann CJ,  et al.
2012-09-04 • PLOS Medicine
2012-09-04 • PLOS Medicine


Background: Increased mortality among men on antiretroviral therapy (ART) has been documented but remains poorly understood. We examined the magnitude of and risk factors for g...
Journal Article
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Research

Prioritising prevention strategies for patients in antiretroviral treatment programmes in resource-limited settings

Spaar A, Graber C, Dabis F, Coutsoudis A, Bachmann L,  et al.
2010-06-01 • AIDS Care
2010-06-01 • AIDS Care
Expanded access to antiretroviral therapy (ART) offers opportunities to strengthen HIV prevention in resource-limited settings. We invited 27 ART programmes from urban settings in Africa...
Journal Article
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Research

Age in antiretroviral therapy programmes in South Africa: a retrospective, multicentre, observational cohort study

Cornell M, Johnson LF, Schomaker M, Tanser F, Maskew M,  et al.
2015-08-03 • Lancet HIV
2015-08-03 • Lancet HIV
BACKGROUND
As access to antiretroviral therapy (ART) expands, increasing numbers of older patients will start treatment and need specialised long-term care. However, the effect of ag...
Journal Article
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Research

Incidence of AIDS-defining and Other Cancers in HIV-positive Children in South Africa: Record Linkage Study

Bohlius J, Maxwell N, Spoerri A, Wainwright R, Sawry S,  et al.
2016-06-01 • Pediatric Infectious Disease Journal
2016-06-01 • Pediatric Infectious Disease Journal
Journal Article
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Research

Tuberculosis and the risk of opportunistic infections and cancers in HIV-infected patients starting ART in Southern Africa

Fenner L, Reid SE, Fox MP, Garone DB, Wellington M,  et al.
2012-11-30 • Tropical Medicine and International Health
2012-11-30 • Tropical Medicine and International Health
To investigate the incidence of selected opportunistic infections (OIs) and cancers and the role of a history of tuberculosis (TB) as a risk factor for developing these conditions in HIV...