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Journal Article
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Research

Independent Origin of Plasmodium falciparum Antifolate Super-Resistance, Uganda, Tanzania, and Ethiopia

Alifrangis M, Nag S, Schousboe ML, Ishengoma D, Lusingu J,  et al.
2014-07-24 • Emerging Infectious Diseases
2014-07-24 • Emerging Infectious Diseases
Super-resistant Plasmodium falciparum threatens the effectiveness of sulfadoxine-pyrimethamine in intermittent preventive treatment for malaria during pregnancy. It is characterized by t...
Journal Article
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Research
Journal Article
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Research

Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malaria

Pearce RJ, Pota H, Evehe M-SB, Ba EH, Mombo-Ngoma G,  et al.
2009-04-14 • PLOS Medicine
2009-04-14 • PLOS Medicine
BACKGROUND: Although the molecular basis of resistance to a number of common antimalarial drugs is well known, a geographic description of the emergence and dispersal of resistance mutat...

Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes

Swarthout TD, van den Broek IVF, Kayembe G, Montgomery JM, Pota H,  et al.
2006-10-01 • Tropical Medicine and International Health
2006-10-01 • Tropical Medicine and International Health
We undertook a trial of artesunate + amodiaquine (AS + AQ) and artesunate + sulphadoxine-pyrimethamine (AS + SP) in 180 children of age 6-59 months with uncomplicated malaria in Democrat...