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Journal Article
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Research

Primary bedaquiline resistance in Karakalpakstan, Uzbekistan

Moe S, Rekart ML, Hernandez D, Sholpan A, Ismailov A,  et al.
2023-05-01 • International Journal of Tuberculosis and Lung Disease
2023-05-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND:
Bedaquiline (BDQ) is widely used in the treatment of rifampicin-resistant TB (RR-TB). However, resistance to BDQ is now emerging. There are no standardised regimens for ...
Journal Article
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Research
Journal Article
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Research

Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis

Harausz EP, Garcia-Prats AJ, Law S, Schaaf HS, Kredo T,  et al.
2018-07-11 • PLOS Medicine
2018-07-11 • PLOS Medicine
An estimated 32,000 children develop multidrug-resistant tuberculosis (MDR-TB; Mycobacterium tuberculosis resistant to isoniazid and rifampin) each year. Little is known about the optima...

Off-label use of bedaquiline in children and adolescents with multidrug-resistant tuberculosis

Achar J, Hewison CCH, Cavalheiro AP, Skrahina A, Cajazeiro J,  et al.
2017-10-01 • Emerging Infectious Diseases
2017-10-01 • Emerging Infectious Diseases
We describe 27 children and adolescents <18 years of age who received bedaquiline during treatment for multidrug-resistant tuberculosis. We report good treatment responses and no cessati...