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Showing 1 - 4 of 4 Items
Showing 1 - 4 of 4 Items
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Journal Article
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Research

Low Resistance to First and Second Line Anti-Tuberculosis Drugs among Treatment Naive Pulmonary Tuberculosis Patients in Southwestern Uganda

Orikiriza P, Tibenderana B, Siedner MJ, Mueller YK, Byarugaba F,  et al.
2015-02-06 • PLOS One
2015-02-06 • PLOS One
There are limited data on region-specific drug susceptibility of tuberculosis (TB) in Uganda. We performed resistance testing on specimens collected from treatment-naive patients with pu...
Journal Article
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Research
Journal Article
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Research
Journal Article
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Research

Population pharmacokinetics and significant under-dosing of anti-tuberculosis medications in people with HIV and critical illness

Rao PS, Moore CC, Mbonde AA, Nuwagira E, Orikiriza P,  et al.
2021-06-18 • Antibiotics
2021-06-18 • Antibiotics
Critical illness from tuberculosis (TB) bloodstream infection results in a high case fatality rate for people living with human immunodeficiency virus (HIV). Critical illness can lead to...

Detection of Plasmodium species by high resolution melt analysis of DNA from blood smears acquired in Southwestern Uganda

Kassaza K, Operario DJ, Nyehangane D, Coffey KC, Namugosa M,  et al.
2017-10-18 • Journal of Clinical Microbiology
2017-10-18 • Journal of Clinical Microbiology
ABSTRACT

Microscopic diagnosis of malaria using Giemsa-stained blood smears is the standard of care in resource-limited se...

Surveillance of Plasmodium falciparum pfcrt haplotypes in southwestern Uganda by high-resolution melt analysis

Kassaza K, Long AC, McDaniels JM, Andre M, Fredrickson W,  et al.
2021-02-25 • Malaria Journal
2021-02-25 • Malaria Journal
BACKGROUND
Chloroquine (CQ) resistance is conferred by mutations in the Plasmodium falciparum CQ resistance transporter (pfcrt). Following CQ withdrawal for anti-malarial treatment, ...