logo
Science Portal
Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
About MSF Science Portal
About
Contact Us
Frequently Asked Questions (FAQs)
Privacy Policy
Terms of Use
Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 12 of 12 Items
Showing 1 - 12 of 12 Items
Sort By: Relevance
  • Newest to oldest
  • Oldest to newest
  • Relevance
Journal Article
|
Research

'I didn't know so many people cared about me': support for patients who interrupt drug-resistant TB treatment

Snyman L, Venables E, Trivino Duran L, Mohr E, Azevedo VD,  et al.
2018-09-01 • International Journal of Tuberculosis and Lung Disease
2018-09-01 • International Journal of Tuberculosis and Lung Disease
SETTING
Early interventions for patients who interrupt their treatment for drug-resistant tuberculosis (DR-TB) are rarely reported and assessed. A novel, patient-centred intervention...
Journal Article
|
Research

Time to ART initiation among patients treated for rifampin-resistant tuberculosis in Khayelitsha, South Africa: Impact on mortality and treatment success

Daniels J, Khogali MA, Mohr E, Cox V, Moyo S,  et al.
2015-11-10 • PLOS One
2015-11-10 • PLOS One
SETTING
Khayelitsha, South Africa, with high burdens of rifampicin-resistant tuberculosis (RR-TB) and HIV co-infection.

OBJECTIVE
To describe time to antiretroviral trea...
Journal Article
|
Research

Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis

Ahmad N, Ahuja SD, Akkerman OW, Alffenaar JWC, Anderson LF,  et al.
2018-09-08 • Lancet
2018-09-08 • Lancet
BACKGROUND
Treatment outcomes for multidrug-resistant tuberculosis remain poor. We aimed to estimate the association of treatment success and death with the use of individual drugs, ...
Journal Article
|
Research

Early safety and efficacy of the combination of bedaquiline and delamanid for the treatment of patients with drug-resistant tuberculosis in Armenia, India, and South Africa: a retrospective cohort study

Ferlazzo G, Mohr E, Laxmeshwar C, Hewison CCH, Hughes J,  et al.
2018-02-13 • Lancet Infectious Diseases
2018-02-13 • Lancet Infectious Diseases
BACKGROUND
Bedaquiline and delamanid have been approved for treatment of multidrug-resistant (MDR) tuberculosis in the past 5 years. Because of theoretical safety concerns, patients ...
Journal Article
|
Research

High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen

Ndjeka N, Schnippel K, Master I, Meintjes GA, Maartens G,  et al.
2018-10-25 • European Respiratory Journal
2018-10-25 • European Respiratory Journal
Background: South African patients with rifampicin-resistant tuberculosis and resistance to fluoroquinolones and/or injectables (pre/XDR-TB) were granted access to bedaquiline through a ...
Journal Article
|
Research

"Life continues": Patient, health care and community care workers perspectives on self-administered treatment for rifampicin-resistant tuberculosis in Khayelitsha, South Africa

Mohr E, Snyman L, Mbakaz Z, Caldwell J, De Azevedo V,  et al.
2018-09-14 • PLOS One
2018-09-14 • PLOS One
BACKGROUND
Self-administered treatment (SAT), a differentiated model of care for rifampicin-resistant tuberculosis (RR-TB), might address adherence challenges faced by patients and h...
Journal Article
|
Research

DOT or SAT for Rifampicin-resistant tuberculosis? A non-randomized comparison in a high HIV-prevalence setting

Mohr E, Daniels J, Beko B, Isaakidis P, Cox V,  et al.
2017-05-18 • PLOS One
2017-05-18 • PLOS One
BACKGROUND
Daily directly-observed therapy (DOT) is recommended for rifampicin-resistant tuberculosis (RR-TB) patients throughout treatment. We assessed the impact of self-administer...
Journal Article
|
Letter

Bedaquiline and delamanid in combination for treatment of drug-resistant tuberculosis

Mohr E, Ferlazzo G, Hewison CCH, De Azevedo V, Isaakidis P
2019-05-01 • Lancet Infectious Diseases
2019-05-01 • Lancet Infectious Diseases
Here we report on the final outcomes for the cohort of 28 patients from Armenia, India, and South Africa who initiated regimens containing the combination of bedaquiline and delamanid fr...
Journal Article
|
Research

Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa

Mohr E, Hughes J, Reuter A, Trivino Duran L, Ferlazzo G,  et al.
2018-05-03 • European Respiratory Journal
2018-05-03 • European Respiratory Journal
Experience with delamanid (Dlm) is limited, particularly among HIV-positive individuals. We describe early efficacy and safety data from a programmatic setting in South Africa. This was ...
Journal Article
|
Research

Early Outcomes of Decentralized Care for Rifampicin-Resistant Tuberculosis in Johannesburg, South Africa: An Observational Cohort Study

Berhanu R, Schnippel K, Mohr E, Hirasen K, Evans D,  et al.
2016-11-03 • PLOS One
2016-11-03 • PLOS One
OBJECTIVE: We describe baseline characteristics, time to treatment initiation and interim patient outcomes at a decentralized, outpatient treatment site for rifampicin-resistant TB (RR-T...
Journal Article
|
Research

Adverse events among people on delamanid for rifampicin-resistant tuberculosis in a high HIV prevalence setting

Hughes J, Reuter A, Chabalala B, Isaakidis P, Cox HS,  et al.
2019-09-01 • International Journal of Tuberculosis and Lung Disease
2019-09-01 • International Journal of Tuberculosis and Lung Disease
SETTING: Patients with rifampicin-resistant tuberculosis (RR-TB) in the township of Khayelitsha, South Africa, were offered delamanid (DLM) within a decentralised RR-TB treatment program...
Journal Article
|
Research

Missed opportunities for earlier diagnosis of rifampicin-resistant tuberculosis despite access to Xpert(®) MTB/RIF

Mohr E, Daniels J, Muller O, Furin J, Chabalala B,  et al.
2017-10-01 • International Journal of Tuberculosis and Lung Disease
2017-10-01 • International Journal of Tuberculosis and Lung Disease
OBJECTIVE
To assess the proportion of rifampicin-resistant tuberculosis (RR-TB) patients with potential earlier RR-TB diagnoses in Khayelitsha, South Africa.

DESIGN
We c...