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Showing 1 - 5 of 5 Items
Showing 1 - 5 of 5 Items
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Journal Article
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Research

The Epidemiology, Pathogenesis, Transmission, Diagnosis, and Management of Multidrug-Resistant, Extensively Drug-Resistant, and Incurable Tuberculosis

Dheda K, Gumbo T, Maartens G, Dooley KE, McNerney R,  et al.
2017-03-15 • Lancet Respiratory Medicine
2017-03-15 • Lancet Respiratory Medicine
Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis remains out of control in several parts of the world including Africa and Asia. Although tube...
Journal Article
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Research

MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era

Beckert P, Sanchez-Padilla E, Merker M, Dreyer V, Kohl TA,  et al.
2020-11-25 • Genome Medicine
2020-11-25 • Genome Medicine
Background
Multidrug-resistant (MDR) Mycobacterium tuberculosis complex strains not detected by commercial molecular drug susceptibility testing (mDST) assays due to the RpoB I491F ...
Journal Article
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Research

Whole genome sequencing reveals complex evolution patterns of multidrug-resistant mycobacterium tuberculosis Beijing strains in patients

Merker M, Kohl TA, Roetzer A, Truebe L, Richter E,  et al.
2013-12-06 • PLOS One
2013-12-06 • PLOS One
Multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains represent a major threat for tuberculosis (TB) control. Treatment of MDR-TB patients is long and less effectiv...
Journal Article
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Research

Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage

Merker M, Blin C, Mona S, Duforet-Frebourg N, Lecher S,  et al.
2015-01-19 • Nature Genetics
2015-01-19 • Nature Genetics
Mycobacterium tuberculosis strains of the Beijing lineage are globally distributed and are associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia. Here w...
Journal Article
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Letter

Detection of drug-resistant tuberculosis by Xpert MTB/RIF in Swaziland

Sanchez-Padilla E, Merker M, Jochims F, Dlamini T, Kahn P,  et al.
2015-03-19 • New England Journal of Medicine
2015-03-19 • New England Journal of Medicine