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Copyright © Médecins Sans Frontières
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Showing 1 - 4 of 4 Items
Showing 1 - 4 of 4 Items
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Journal Article
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Research

Mutational correlates of virological failure in individuals receiving a WHO-recommended tenofovir-containing first-line regimen: Aa international collaboration

Rhee SY, Varghese B, Holmes SP, Van Zyl GU, Steegen K,  et al.
2017-03-19 • EBioMedicine
2017-03-19 • EBioMedicine
Tenofovir disoproxil fumarate (TDF) genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF) on a WHO-recommended TDF-cont...
Journal Article
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Research

Development of dual-class antiretroviral drug resistance in a child coinfected with HIV and tuberculosis: a case report from KwaZulu-Natal, South Africa

Murphy RA, France H, Sunpath H, Gordon ML, Marconi VC,  et al.
2009-02-01 • Journal of Tropical Pediatrics
2009-02-01 • Journal of Tropical Pediatrics
The treatment of concurrent HIV and tuberculosis (TB) in children <3 years of age has not been well-studied and is complicated by potential drug-drug interactions. The recommended antire...
Journal Article
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Research

Coadministration of lopinavir/ritonavir and rifampicin in HIV and tuberculosis co-infected adults in South Africa

Murphy RA, Marconi VC, Gandhi R, Kuritzkes DR, Sunpath H
2012-09-28 • PLOS One
2012-09-28 • PLOS One
In HIV-infected patients receiving rifampicin-based treatment for tuberculosis (TB), the dosage of lopinavir/ritonavir (LPV/r) is adjusted to prevent sub-therapeutic lopinavir concentrat...
Journal Article
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Research

Early warning indicators for first-line virologic failure independent of adherence measures in a South African urban clinic

Marconi VC, Wu B, Hampton J, Ordonez CE, Johnson BA,  et al.
2013-12-09 • AIDS Patient Care and STDs
2013-12-09 • AIDS Patient Care and STDs
Abstract We sought to develop individual-level Early Warning Indicators (EWI) of virologic failure (VF) for clinicians to use during routine care complementing WHO population-level EWI. ...