Search Results | MSF Science Portal

Journal Article

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Short Report

Broger T, Marx FM, Theron G, Marais BJ, Nicol MP, et al.

2024-07-01 • Lancet Global Health

Journal Article

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Research

du Cros PAK, Greig J, Cross GB, Cousins C, Berry C, et al.

2023-12-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
The value, speed of completion and robustness of the evidence generated by TB treatment trials could be improved by implementing standards for best practice.

METH...

Journal Article

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Commentary

Deborggraeve S, Casenghi M, Hewison CCH, Ditekemena J, Ditiu L, et al.

2023-09-11 • Lancet Child and Adolescent Health

Journal Article

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Research

Chiang SS, Graham SM, Schaaf HS, Marais BJ, Sant’Anna CC, et al.

2023-08-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
These clinical standards aim to provide guidance for diagnosis, treatment, and management of drug-susceptible TB in children and adolescents.

METHODS
Fifty-tw...

Journal Article

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Research

Bonnet MMB, Nordholm AC, Ssekyanzi B, Byamukama O, Orikiriza P, et al.

2023-03-23 • Pediatrics

BACKGROUND AND OBJECTIVES:
Children experience high tuberculosis (TB)-related mortality but causes of death among those with presumptive TB are poorly documented. We describe the mor...

Journal Article

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Research

Gunasekera KS, Marcy O, Muñoz J, Lopez-Varela E, Sekadde MP, et al.

2023-03-13 • Lancet Child and Adolescent Health

BACKGROUND
Many children with pulmonary tuberculosis remain undiagnosed and untreated with related high morbidity and mortality. Recent advances in childhood tuberculosis algorithm d...

Journal Article

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Commentary

Chiang SS, Waterous PM, Atieno VF, Bernays S, Bondarenko Y, et al.

2023-03-01 • Journal of Adolescent Health

Journal Article

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Research

Orikiriza P, Smith JS, Ssekyanzi B, Nyehangane D, Mugisha IT, et al.

2021-06-17 • European Respiratory Journal

BACKGROUND
Non-sputum-based diagnostic approaches are crucial in children at high risk of disseminated tuberculosis (TB) who cannot expectorate sputum. We evaluated the diagnostic ac...

Journal Article

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Commentary

Nash M, Perrin C, Seddon JA, Furin J, Hauser J, et al.

2020-12-01 • Lancet Child and Adolescent Health

Journal Article

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Short Report

Harries AD, Marais BJ, Kool B, Ram S, Kumar AMV, et al.

2014-06-21 • Public Health Action

Journal Article

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Review

Abubakar I, Zignol M, Falzon D, Raviglione M, Ditui L, et al.

2013-03-24 • Lancet Infectious Diseases

Journal Article

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Review

Bissel K, Viney K, Brostom R, Gounder S, Khogali MA, et al.

2014-06-21 • Public Health Action

Operational research (OR) in public health aims to investigate strategies, interventions, tools or knowledge that can enhance the quality, coverage, effectiveness or performance of healt...

Journal Article

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Review

Zumla A, Abubakar I, Raviglione M, Hoelscher M, Ditui L, et al.

2012-04-03 • Journal of Infectious Diseases

Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short cour...

Journal Article

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Review

Harausz EP, Garcia-Prats AJ, Seddon JA, Schaaf HS, Hesseling AC, et al.

2016-11-17 • American Journal of Respiratory and Critical Care Medicine

It is estimated that 33,000 children develop multidrug-resistant tuberculosis (MDR-TB) each year. In spite of these numbers, children and adolescents have limited access to the new and r...

Journal Article

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Research

Migliori GB, Tiberi S, Zumla A, Petersen E, Chakaya JM, et al.

2020-02-01 • International Journal of Infectious Diseases

The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at provid...

Journal Article

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Review

Brigden G, Furin J, van Gulik C, Marais BJ

2015-03-05 • Expert Review of Anti-Infective Therapy

Children were often the forgotten victims of the global tuberculosis (TB) epidemic, neglected by traditional TB services as well as maternal and child health initiatives. Luckily this is...

Journal Article

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Research

Hill P, Dye C, Viney K, Tabutoa K, Kienene T, et al.

2014-08-01 • International Journal of Tuberculosis and Lung Disease

SETTING
The global target of tuberculosis (TB) elimination by 2050 requires new approaches. Active case finding plus mass prophylactic treatment has been disappointing. We consider m...

Journal Article

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Commentary

Migliori GB, Marx FM, Ambrosino N, Zampogna E, Schaaf HS, et al.

2021-10-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
Increasing evidence suggests that post-TB lung disease (PTLD) causes significant morbidity and mortality. The aim of these clinical standards is to provide guidance on the...

Journal Article

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Review

McNerney R, Maeurer M, Abubakar I, Marais BJ, McHugh TD, et al.

2012-04-10 • Journal of Infectious Diseases

Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to...

Journal Article

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Research

Migliori GB, Wu SJ, Matteelli A, Zenner D, Goletti D, et al.

2022-03-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
Tuberculosis (TB) preventive therapy (TPT) decreases the risk of developing TB disease and its associated morbidity and mortality. The aim of these clinical standards is t...

Science Portal

Diagnostic yield as an important metric for the evaluation of novel tuberculosis tests: rationale and guidance for future research

Standards for clinical trials for treating TB

Reversing the neglect of children and adolescents affected by tuberculosis

Clinical standards for drug-susceptible TB in children and adolescents

Mortality and cause of death in children with presumptive disseminated tuberculosis

Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis

Caring for adolescents and young adults with tuberculosis or at risk of tuberculosis: Consensus statement from an international expert panel

Tuberculosis diagnostic accuracy of stool Xpert MTB/RIF and urine AlereLAM in vulnerable children

Access to paediatric formulations for the treatment of childhood tuberculosis

Mentorship for operational research capacity building: hands-on or hands-off? (D/N analyze when looking at MSF Pubs Dataset)

Eye exam with indirect ophthalmoscopy for diagnosis of disseminated tuberculosis in patients with HIV/AIDS

Building operational research capacity in the Pacific

Drug-Resistant Tuberculosis--Current dilemmas, unanswered questions, challenges, and priority needs

New and repurposed drugs for pediatric multidrug-resistant tuberculosis. Practice-based recommendations

MDR/XDR-TB management of patients and contacts: challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network

Getting it right for children: improving tuberculosis treatment access and new treatment options

Mass treatment to eliminate tuberculosis from an island population

Clinical standards for the assessment, management and rehabilitation of post-TB lung disease

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities

Clinical standards for the diagnosis, treatment and prevention of TB infection