logo
Science Portal
Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
About MSF Science Portal
About
Contact Us
Frequently Asked Questions (FAQs)
Privacy Policy
Terms of Use
Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 20 of 40 Items
Showing 1 - 20 of 40 Items
Sort By: Relevance
  • Newest to oldest
  • Oldest to newest
  • Relevance
Journal Article
|
Research

Bedaquiline resistance and treatment outcomes among patients with tuberculosis previously exposed to bedaquiline in India: A multicentric retrospective cohort study

Singla R, Khan S, Silsarma A, Chavan V, Mahajan R,  et al.
2025-03-13 • Clinical Infectious Diseases
2025-03-13 • Clinical Infectious Diseases

BACKGROUND

Bedaquiline (BDQ) resistance presents a critical challenge in the fight against tuberculosis (TB), particularly multidrug-resistant (MDR) strains. Th...

Journal Article
|
Research

Concomitant bedaquiline and delamanid therapy in patients with drug-resistant extra-pulmonary tuberculosis in Mumbai, India

Mongia H, Mamnoon F, Silsarma A, Mahajan R, Dalal A,  et al.
2024-04-01 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
2024-04-01 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
BACKGROUND
World Health Organization suggests concurrent bedaquiline-delamanid (BDQ-DLM) as part of individualised regimens for eligible patients with pulmonary drug-resistant tuberc...
Journal Article
|
Letter

Linezolid resistance in patients with drug-resistant TB

Vengurlekar D, Walker C, Mahajan R, Dalal A, Chavan VV,  et al.
2023-07-01 • International Journal of Tuberculosis and Lung Disease
2023-07-01 • International Journal of Tuberculosis and Lung Disease
Journal Article
|
Research

Operationalising targeted next-generation sequencing for routine diagnosis of drug-resistant TB

Iyer AS, Ndlovu Z, Sharma J, Mansoor H, Bharati M,  et al.
2023-06-21 • Public Health Action
2023-06-21 • Public Health Action
BACKGROUND
Phenotypic drug susceptibility testing (pDST) for Mycobacterium tuberculosis can take up to 8 weeks, while conventional molecular tests identify a limited set of resistanc...
Journal Article
|
Commentary

Caring for adolescents and young adults with tuberculosis or at risk of tuberculosis: Consensus statement from an international expert panel

Chiang SS, Waterous PM, Atieno VF, Bernays S, Bondarenko Y,  et al.
2023-03-01 • Journal of Adolescent Health
2023-03-01 • Journal of Adolescent Health
Journal Article
|
Research

Clinical utility of target-based next-generation sequencing for drug-resistant TB

Mansoor H, Hirani N, Chavan VV, Das M, Sharma J,  et al.
2023-01-01 • International Journal of Tuberculosis and Lung Disease
2023-01-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
In high TB burden countries, access to drug susceptibility testing is a major bottleneck. Targeted next-generation sequencing (tNGS) is a promising technology for rapid re...
Conference Material
|
Poster

Treatment outcomes among drug-resistant children below 10 years treated with newer drugs, in Médecins Sans Frontieres clinic in Mumbai, India

Singh SN, Singh P, Silsarma A, Iyer AS, Galindo MA,  et al.
2022-11-30 • MSF Paediatric Days 2022
2022-11-30 • MSF Paediatric Days 2022
Journal Article
|
Research

Ambulatory Multi-Drug Resistant Tuberculosis Treatment Outcomes in a Cohort of HIV-Infected Patients in a Slum Setting in Mumbai, India

Isaakidis P, Cox HS, Varghese B, Montaldo C, Da Silva E,  et al.
2011-12-01 • PLOS One
2011-12-01 • PLOS One
India carries one quarter of the global burden of multi-drug resistant TB (MDR-TB) and has an estimated 2.5 million people living with HIV. Despite this reality, provision of treatment f...
Journal Article
|
Research

Surgical interventions for pulmonary tuberculosis in Mumbai, India: Surgical outcomes and programmatic challenges India: surgical outcomes and programmatic challenges

Shirodkar S, Anande L, Dalal A, Desai C, Correa G,  et al.
2016-09-21 • Public Health Action
2016-09-21 • Public Health Action
SETTING
While surgery for pulmonary tuberculosis (PTB) is considered an important adjunct for specific cases, including drug-resistant tuberculosis, operational evidence on its feasi...
Journal Article
|
Research

Treatment outcomes of children and adolescents receiving drug-resistant TB treatment in a routine TB programme, Mumbai, India

Dhakulkar S, Das M, Sutar N, Oswal V, Shah D,  et al.
2021-02-18 • PLOS One
2021-02-18 • PLOS One
BACKGROUND
Childhood and adolescent drug-resistant TB (DR-TB) is one of the neglected infectious diseases. Limited evidence exists around programmatic outcomes of children and adoles...
Journal Article
|
Letter

Linezolid in drug-resistant tuberculosis: haste makes waste

Hughes J, Isaakidis P, Andries A, Mansoor H, Cox V,  et al.
2015-12-01 • European Respiratory Journal
2015-12-01 • European Respiratory Journal
Journal Article
|
Short Report

Treating All Multidrug-Resistant Tuberculosis Patients, Not Just Bacteriologically Confirmed Cases

Das M, Isaakidis P, Van der Bergh R, Kumar AMV, Sharath BN,  et al.
2016-06-21 • Public Health Action
2016-06-21 • Public Health Action
Journal Article
|
Research

Treatment outcomes in a cohort of patients with chronic hepatitis B and human immunodeficiency virus co-infection in Mumbai, India

Isaakidis P, Mansoor H, Zachariah R, Da Silva E, Varghese B,  et al.
2012-08-24 • International Health
2012-08-24 • International Health
Treatment experiences with patients co-infected with human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in resource-limited settings remain poorly documented. This study aime...
Journal Article
|
Research

Second-line failure and first experience with third-line antiretroviral therapy in Mumbai, India

Khan S, Das M, Andries A, Deshpande A, Mansoor H,  et al.
2014-07-30 • Global Health Action
2014-07-30 • Global Health Action
There are limited data on the failure of second-line antiretroviral therapy (ART) and the use of third-line ART in people living with HIV in resource-limited settings. Since 2011, the Mé...
Journal Article
|
Research

Self-Administered Tuberculosis Treatment Outcomes in a Tribal Population on the Indo-Myanmar Border, Nagaland, India

Das M, Isaakidis P, Shenoy R, Anicete R, Sharma H,  et al.
2014-09-26 • PLOS One
2014-09-26 • PLOS One
Multiple strategies are being adopted by national tuberculosis (TB) programmes to achieve universal coverage of tuberculosis treatment. However, populations living in 'hard-to-reach' are...
Journal Article
|
Research

Ambulatory management of pre- and extensively drug resistant tuberculosis patients with imipenem delivered through port-a-cath: A mixed methods study on treatment outcomes and challenges

Chavan VV, Dalal A, Nagaraja SB, Thekkur P, Mansoor H,  et al.
2020-06-16 • PLOS One
2020-06-16 • PLOS One
Background
Imipenem, an intravenous antibiotic is recommended for use in drug resistant tuberculosis (DR-TB) when an effective regimen with combination of other second line drugs is...
Journal Article
|
Research

Ocular inflammatory disease and ocular tuberculosis in a cohort of patients co-infected with HIV and multidrug-resistant tuberculosis in Mumbai, India: a cross-sectional study

mehta, Mansoor H, Khan S, Saranchuk P, Isaakidis P
2013-05-20 • BMC Infectious Diseases
2013-05-20 • BMC Infectious Diseases
The prevalence and the patterns of ocular inflammatory disease and ocular tuberculosis (TB) are largely undocumented among Multidrug Resistant TB (MDR-TB) patients co-infected with Human...
Journal Article
|
Research

Challenging drug-resistant TB treatment journey for children, adolescents and their care-givers: A qualitative study

Das M, Mathur T, Ravi S, Meneguim A, Iyer AS,  et al.
2021-03-10 • PLOS One
2021-03-10 • PLOS One
Background: Childhood multidrug-resistant TB (MDR-TB) still affects around 25000 children every year across the globe. Though the treatment success rates for drug-resistant TB (DR-TB) in...
Journal Article
|
Letter

Linezolid for multidrug-resistant tuberculosis in HIV-infected and -uninfected patients

Hughes J, Isaakidis P, Andries A, Mansoor H, Cox V,  et al.
2015-04-02 • European Respiratory Journal
2015-04-02 • European Respiratory Journal
Journal Article
|
Research

Routine viral load monitoring and enhanced adherence counselling at a public ART centre in Mumbai, India

Laxmeshwar C, Acharya S, Das M, Keskar P, Pazare A,  et al.
2020-05-05 • PLOS One
2020-05-05 • PLOS One
BACKGROUND
Routine viral-load (VL) measurements along with enhanced adherence counselling (EAC) are recommended to achieve virological suppression among people living with HIV/AIDS (...