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PLoS Negl Trop Dis. 2010 December 21; Volume 4 (Issue 12); DOI:10.1371/journal.pntd.0000783
Lindner AK, Priotto G
PLoS Negl Trop Dis. 2010 December 21; Volume 4 (Issue 12); DOI:10.1371/journal.pntd.0000783
Children with human African trypanosomiasis (HAT) present with a range of generally non-specific symptoms. Late diagnosis is frequent with often tragic outcomes. Trypanosomes can infect the foetus by crossing the placenta. Unequivocal cases of congenital infection that have been reported include newborn babies of infected mothers who were diagnosed with HAT in the first 5 days of life and children of infected mothers who had never entered an endemic country themselves.