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Copyright © Médecins Sans Frontières
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Showing 1 - 5 of 5 Items
Showing 1 - 5 of 5 Items
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Journal Article
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Research

Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis

WorldWide Antimalarial Resistance Network Methodology Study Group, Dahal P, Simpson JA, Abdulla S, Achan J,  et al.
2019-07-05 • Malaria Journal
2019-07-05 • Malaria Journal
BACKGROUND
Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potenti...
Journal Article
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Research

Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial

Smithuis FM, Kyaw MK, Phe O, Win T, Aung PP,  et al.
2010-10-01 • Lancet Infectious Diseases
2010-10-01 • Lancet Infectious Diseases
BACKGROUND: Artemisinin-combination therapy (ACT) is recommended as first-line treatment of falciparum malaria throughout the world, and fixed-dose combinations are preferred by WHO; whe...
Journal Article
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Research

The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malaria

Lee SJ, Stepniewska K, Anstey NM, Ashley EA, Barnes KI,  et al.
2008-08-01 • Malaria Journal
2008-08-01 • Malaria Journal
BACKGROUND: Malaria is a very important cause of anaemia in tropical countries. Anaemia is assessed either by measurement of the haematocrit or the haemoglobin concentration. For compari...
Journal Article
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Research

Practical methods to permit the analysis of host biomarkers in resource-limited settings

Chandna A, Richard-Greenblatt M, Tustin R, Lee SJ, Kain KC,  et al.
2022-04-18 • American Journal of Tropical Medicine and Hygiene
2022-04-18 • American Journal of Tropical Medicine and Hygiene
Host biomarker testing can be used as an adjunct to the clinical assessment of patients with infections and might be particularly impactful in resource-constrained settings. Research on ...
Journal Article
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Research

In vivo parasitological measures of artemisinin susceptibility

Stepniewska K, Ashley EA, Lee SJ, Anstey NM, Barnes KI,  et al.
2010-02-15 • Journal of Infectious Diseases
2010-02-15 • Journal of Infectious Diseases
Parasite clearance data from 18,699 patients with falciparum malaria treated with an artemisinin derivative in areas of low (n=14,539), moderate (n=2077), and high (n=2083) levels of mal...