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Showing 1 - 7 of 7 Items
Showing 1 - 7 of 7 Items
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Research

A Worldwide Map of Plasmodium Falciparum K13-Propeller Polymorphisms

Ménard D, Khim N, Beghain J, Adegnika AA, Alam MS,  et al.
2016-06-23 • New England Journal of Medicine
2016-06-23 • New England Journal of Medicine
Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P...
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Journal Article
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Research

Diagnostic accuracy of the small membrane filtration method for diagnosis of pulmonary tuberculosis in a high HIV prevalence setting

Kim S, Orikiriza P, Acuña-Villaorduña C, Vinhas S, Bonnet MMB,  et al.
2016-03-30 • Journal of Clinical Microbiology
2016-03-30 • Journal of Clinical Microbiology
Sputum acid-fast bacilli (AFB) smear microscopy has suboptimal sensitivity but remains the most commonly used laboratory test to diagnose pulmonary tuberculosis (TB). We prospectively ev...

Adapting Reactive Case Detection Strategies for falciparum Malaria in a Low-Transmission Area in Cambodia

Rossi G, Van der Bergh R, Nguon C, Debackere M, Vernaeve L,  et al.
2017-09-04 • Clinical Infectious Diseases
2017-09-04 • Clinical Infectious Diseases
Reactive case detection around falciparum malaria cases in Cambodia presents a low output. We improved it by including individuals occupationally coexposed with index case patients and u...

Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis

Pfeffer DA, Ley B, Howes RE, Adu P, Alam MS,  et al.
2020-05-14 • PLOS Medicine
2020-05-14 • PLOS Medicine

BACKGROUND

The...

Closing in on the Reservoir: Proactive Case Detection in High-Risk Groups as a Strategy to Detect Plasmodium falciparum Asymptomatic Carriers in Cambodia

Rossi G, Vernaeve L, Van der Bergh R, Nguon C, Debackere M,  et al.
2018-01-18 • Clinical Infectious Diseases
2018-01-18 • Clinical Infectious Diseases
In the frame of elimination strategies of Plasmodium falciparum (Pf), active case detection has been recommended as complementary approach to the existing passive case detection programs...

Effect of previous treatment and sputum quality on diagnostic accuracy of Xpert(®) MTB/RIF

Acuña-Villaorduña C, Orikiriza P, Nyehangane D, White LJ, Mwanga-Amumpaire J,  et al.
2017-04-01 • International Journal of Tuberculosis and Lung Disease
2017-04-01 • International Journal of Tuberculosis and Lung Disease
SETTING
In early studies, Xpert® MTB/RIF accurately detected culture-proven pulmonary tuberculosis (TB). Recent reports have, however, found a lower than expected specificity in prev...

Malaria PCR detection in Cambodian low-transmission settings: dried blood spots versus venous Blood Samples

Canier L, Khim N, Kim S, Eam R, Khean C,  et al.
2015-01-05 • American Journal of Tropical Medicine and Hygiene
2015-01-05 • American Journal of Tropical Medicine and Hygiene
In the context of malaria elimination, novel strategies for detecting very low malaria parasite densities in asymptomatic individuals are needed. One of the major limitations of the mala...