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Showing 1 - 6 of 6 Items
Showing 1 - 6 of 6 Items
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Journal Article
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Research

High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola

Guthmann JP, Cohuet S, Rigutto C, Fortes F, Saraiva N,  et al.
2006-07-01 • American Journal of Tropical Medicine and Hygiene
2006-07-01 • American Journal of Tropical Medicine and Hygiene
In April 2004, 137 children 6-59 months of age with uncomplicated Plasmodium falciparum (Pf) malaria (Caala, Central Angola) were randomized to receive either artemether-lumefantrine (Co...
Journal Article
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Research

Malaria in camps for internally-displaced persons in Uganda: evaluation of an insecticide-treated bednet distribution programme

Spencer S, Grant AD, Piola P, Tukpo K, Okia M,  et al.
2004-12-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2004-12-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Malaria is a key health problem among displaced populations in malaria-endemic areas. Mass distribution of insecticide-treated bednets (ITN) to prevent malaria is often carried out in co...
Journal Article
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Research

Supervised versus unsupervised intake of six-dose artemether-lumefantrine for treatment of acute, uncomplicated Plasmodium falciparum malaria in Mbarara, Uganda: a randomised trial

Piola P, Fogg C, Bajunirwe F, Biraro S, Grandesso F,  et al.
2005-04-23 • Lancet
2005-04-23 • Lancet
BACKGROUND: The six-dose regimen of artemether-lumefantrine is effective and is among combination therapies prioritised to replace antimalarials that no longer work in Africa. However, i...
Journal Article
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Research

Molecular genotyping in a malaria treatment trial in Uganda - unexpected high rate of new infections within 2 weeks after treatment

Mugittu K, Priotto G, Guthmann JP, Kiguli J, Adjuik M,  et al.
2007-02-01 • Tropical Medicine and International Health
2007-02-01 • Tropical Medicine and International Health
Polymerase chain reaction (PCR) genotyping of malaria parasites in drug efficacy trials helps differentiate reinfections from recrudescences. A combination therapy trial of one (n = 115)...
Journal Article
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Research

Assessment of three new parasite lactate dehydrogenase (pan-pLDH) tests for diagnosis of uncomplicated malaria

Fogg C, Twesigye R, Batwala V, Piola P, Nabasumba C,  et al.
2008-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
A study to assess the diagnostic capabilities of three parasite lactate dehydrogenase (pan-pLDH) tests, Vistapan), Carestart and Parabank), was conducted in Uganda. An HRP2 test, Parache...
Journal Article
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Research

Validity, reliability and ease of use in the field of five rapid tests for the diagnosis of Plasmodium falciparum malaria in Uganda

Guthmann JP, Ruiz A, Priotto G, Kiguli J, Bonte L,  et al.
2008-02-14 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-02-14 • Transactions of the Royal Society of Tropical Medicine and Hygiene
A study was conducted to measure the overall performance of several rapid diagnostic tests for Plasmodium falciparum infection, in order to select the most appropriate test to be used in...