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Showing 1 - 5 of 5 Items
Showing 1 - 5 of 5 Items
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Journal Article
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Research

Population pharmacokinetics of pediatric lopinavir/ritonavir oral pellets in children living with HIV in Africa

Chupradit S, Wamalwa DC, Maleche‐Obimbo E, Kekitiinwa AR, Mwanga‐Amumpaire J,  et al.
2024-05-01 • Clinical Pharmacology & Therapeutics
2024-05-01 • Clinical Pharmacology & Therapeutics
Antiretroviral therapy for children living with HIV (CLHIV) under 3 years of age commonly includes lopinavir/ritonavir (LPV/r). However, the original liquid LPV/r formulation has taste a...
Journal Article
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Research

Abacavir drug exposures in African children under 14 kg using paediatric solid fixed dose combinations according to World Health Organization weight bands

Chupradit S, Wamalwa DC, Maleche-Obimbo E, Kekitiinwa AR, Mwanga-Amumpaire J,  et al.
2023-10-05 • Journal of the Pediatric Infectious Diseases Society
2023-10-05 • Journal of the Pediatric Infectious Diseases Society
BACKGROUND
The pharmacokinetics of abacavir (ABC) in African children living with HIV (CLHIV) weighing < 14 kg and receiving pediatric fixed dose combinations (FDC) according to WHO ...
Journal Article
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Research

Acceptability of a new 4-in-1 Abacavir/Lamivudine/Lopinavir/Ritonavir paediatric fixed-dose combination: the caregiver–child dyads’ perspective

Rotsaert A, Ogara C, Mwanga-Amumpaire J, Kekitiinwa AR, Musiime V,  et al.
2023-01-01 • Therapeutic Advances in Infectious Disease
2023-01-01 • Therapeutic Advances in Infectious Disease
BACKGROUND
Worldwide, 1.7 million children younger than 15 years were living with HIV in 2021. Only 52% of them had access to antiretrovirals (ARVs). Lack of age-appropriate ARV form...
Journal Article
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Research

The epidemiology of adolescents living with perinatally acquired HIV: A cross-region global cohort analysis

Slogrove AL, Schomaker M, Davies MA, Williams P, Balkan S,  et al.
2018-03-01 • PLOS Medicine
2018-03-01 • PLOS Medicine
Globally, the population of adolescents living with perinatally acquired HIV (APHs) continues to expand. In this study, we pooled data from observational pediatric HIV cohorts and cohort...
Journal Article
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Research

Multi-Country Validation of SAMBA - A Novel Molecular Point-of- Care Test for HIV-1 Detection in Resource-Limited Setting

Ondiek J, Namukaya Z, Mtapuri-Zinyowera S, Balkan S, Elbireer A,  et al.
2017-06-09 • Journal of Acquired Immune Deficiency Syndromes (1999)
2017-06-09 • Journal of Acquired Immune Deficiency Syndromes (1999)
Early diagnosis of HIV-1 infection and the prompt initiation of antiretroviral therapy are critical to achieving a reduction in the morbidity and mortality of infected infants. The SAMBA...