Showing 1 - 16 of 16 Items
Showing 1 - 16 of 16 Items
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Journal Article
|Research
2023-09-15 • ACG Case Reports Journal
2023-09-15 • ACG Case Reports Journal
BACKGROUND
Literature reviews (LRs) identify, evaluate, and synthesize relevant papers to a particular research question to advance understanding and support decision-making. However...
Literature reviews (LRs) identify, evaluate, and synthesize relevant papers to a particular research question to advance understanding and support decision-making. However...
Journal Article
|Research
2013-02-28 • PLOS One
2013-02-28 • PLOS One
OBJECTIVES
Mortality in patients starting antiretroviral therapy (ART) is higher in Malawi and Zambia than in South Africa. We examined whether different monitoring of ART (viral loa...
Mortality in patients starting antiretroviral therapy (ART) is higher in Malawi and Zambia than in South Africa. We examined whether different monitoring of ART (viral loa...
Journal Article
|Research
2012-09-17 • Pediatrics
2012-09-17 • Pediatrics
BACKGROUND
Poor growth is an indication for antiretroviral therapy (ART) and a criterion for treatment failure. We examined variability in growth response to ART in 12 programs in Ma...
Poor growth is an indication for antiretroviral therapy (ART) and a criterion for treatment failure. We examined variability in growth response to ART in 12 programs in Ma...
Journal Article
|Research
2014-09-09 • PLOS Medicine
2014-09-09 • PLOS Medicine
BACKGROUND
High early mortality in patients with HIV-1 starting antiretroviral therapy (ART) in sub-Saharan Africa, compared to Europe and North America, is well documented. Longer-t...
High early mortality in patients with HIV-1 starting antiretroviral therapy (ART) in sub-Saharan Africa, compared to Europe and North America, is well documented. Longer-t...
Journal Article
|Research
2010-08-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2010-08-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in chi...
Journal Article
|Research
2009-09-10 • AIDS
2009-09-10 • AIDS
BACKGROUND
In high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring ...
In high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring ...
Journal Article
|Research
2013-04-09 • PLOS Medicine
2013-04-09 • PLOS Medicine
Few estimates exist of the life expectancy of HIV-positive adults receiving antiretroviral treatment (ART) in low- and middle-income countries. We aimed to estimate the life expectancy o...
Journal Article
|Research
2015-07-07 • Journal of Acquired Immune Deficiency Syndromes (1999)
2015-07-07 • Journal of Acquired Immune Deficiency Syndromes (1999)
Journal Article
|Research
2013-09-01 • AIDS
2013-09-01 • AIDS
OBJECTIVES
Zidovudine (ZDV) is recommended for first-line antiretroviral therapy (ART) in resource-limited settings. ZDV may, however, lead to anemia and impaired immunological respo...
Zidovudine (ZDV) is recommended for first-line antiretroviral therapy (ART) in resource-limited settings. ZDV may, however, lead to anemia and impaired immunological respo...
Journal Article
|Research
2014-10-23 • AIDS
2014-10-23 • AIDS
OBJECTIVES
Many paediatric antiretroviral therapy (ART) programmes in Southern Africa rely on CD4⁺ to monitor ART. We assessed the benefit of replacing CD4⁺ by viral load monitoring....
Many paediatric antiretroviral therapy (ART) programmes in Southern Africa rely on CD4⁺ to monitor ART. We assessed the benefit of replacing CD4⁺ by viral load monitoring....
Journal Article
|Research
2012-09-01 • Tropical Medicine and International Health
2012-09-01 • Tropical Medicine and International Health
OBJECTIVES
To determine the improvement in positive predictive value of immunological failure criteria for identifying virological failure in HIV-infected children on antiretroviral ...
To determine the improvement in positive predictive value of immunological failure criteria for identifying virological failure in HIV-infected children on antiretroviral ...
Journal Article
|Research
2011-03-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2011-03-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determ...
Journal Article
|Research
2008-07-08 • PLOS Medicine
2008-07-08 • PLOS Medicine
BACKGROUND: The provision of highly active antiretroviral therapy (HAART) in resource-limited settings follows a public health approach, which is characterised by a limited number of reg...
Journal Article
|Research
2009-10-01 • South African Medical Journal
2009-10-01 • South African Medical Journal
OBJECTIVES: To assess paediatric antiretroviral treatment (ART) outcomes and their associations from a collaborative cohort representing 20% of the South African national treatment progr...
Journal Article
|Research
2011-08-11 • Tropical Medicine and International Health
2011-08-11 • Tropical Medicine and International Health
Objectives To determine the diagnostic accuracy of World Health Organization (WHO) 2010 and 2006 as well as United States Department of Health and Human Services (DHHS) 2008 definitions...
Journal Article
|Research
2012-03-20 • AIDS
2012-03-20 • AIDS
In low-income settings, treatment failure is often identified using CD4 cell count monitoring. Consequently, patients remain on a failing regimen, resulting in a higher risk of transmiss...