Psychosocial challenges impact patients’ ability to remain on antiretroviral therapy lifelong, magnified by disorganized health-systems and healthcare worker (HCW) attitudes. To address ...
van Heerden JK, Meintjes G, Barr D, Zhao Y, Griesel R, et al.
2024-03-01 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
2024-03-01 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
BACKGROUND Tenofovir diphosphate (TFV-DP) concentration in dried blood spots is a marker of long-term adherence. We investigated the relationship between TFV-DP concentrations and vi...
Griesel R, Zhao Y, Simmons B, Omar Z, Wiesner L, et al.
2023-05-22 • Lancet HIV
2023-05-22 • Lancet HIV
BACKGROUND The drug-drug interaction between rifampicin and dolutegravir can be overcome by supplemental dolutegravir dosing, which is difficult to implement in high-burden settings....
Nhemachena T, Späth C, Arendse KD, Lebelo K, Zokufa N, et al.
2023-01-26 • BMC Primary Care
2023-01-26 • BMC Primary Care
BACKGROUND & OBJECTIVES The benefits of long-term adherence to antiretroviral therapy (ART) are countered by interruptions in care or disengagement from care. Healthcare workers (HCW...
Wilkinson LS, Grimsrud A, Cassidy T, Orrell C, Voget J, et al.
2019-07-30 • BMC Infectious Diseases
2019-07-30 • BMC Infectious Diseases
BACKGROUND:
The antiretroviral therapy (ART) adherence club (AC) differentiated service delivery model, where clinically stable ART patients receive their ART refills and psychosoci...
Keene CM, Zokufa N, Venables E, Wilkinson LS, Hoffman R, et al.
2020-07-08 • BMJ Open
2020-07-08 • BMJ Open
OBJECTIVE Longer intervals between routine clinic visits and medication refills are part of patient-centred, differentiated service delivery (DSD). They have been shown to improve pa...
Cassidy T, Grimsrud A, Keene CM, Lebelo K, Hayes H, et al.
2020-12-01 • Journal of the International AIDS Society
2020-12-01 • Journal of the International AIDS Society
INTRODUCTION The antiretroviral therapy (ART) adherence club (AC) model has supported clinically stable HIV patients’ retention with group ART refills and psychosocial support. Reduc...