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Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 9 of 9 Items
Showing 1 - 9 of 9 Items
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Journal Article
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Research

Longer-term virologic outcomes on tenofovir-lamivudine-dolutegravir in second-line ART

Van Heerden JK, Zhao Y, Keene CM, Griesel R, Omar Z,  et al.
2025-04-30 • South African Journal of HIV Medicine
2025-04-30 • South African Journal of HIV Medicine

BACKGROUND

Dol...

Journal Article
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Research

Supporting re-engagement with HIV services after treatment interruption in South Africa: a mixed method program evaluation of MSF’s Welcome Service

Arendse KD, Walker C, Pfaff C, Lebelo K, Cassidy T,  et al.
2024-03-27 • Scientific Reports
2024-03-27 • Scientific Reports
Psychosocial challenges impact patients’ ability to remain on antiretroviral therapy lifelong, magnified by disorganized health-systems and healthcare worker (HCW) attitudes. To address ...
Journal Article
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Research

Relationship between tenofovir diphosphate concentrations in dried blood spots and virological outcomes after initiating tenofovir-lamivudine-dolutegravir as first-line or second-line antiretroviral therapy

van Heerden JK, Meintjes G, Barr D, Zhao Y, Griesel R,  et al.
2024-03-01 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
2024-03-01 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
BACKGROUND
Tenofovir diphosphate (TFV-DP) concentration in dried blood spots is a marker of long-term adherence. We investigated the relationship between TFV-DP concentrations and vi...
Journal Article
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Research

Standard-dose versus double-dose dolutegravir in HIV-associated tuberculosis in South Africa (RADIANT-TB): a phase 2, non-comparative, randomised controlled trial

Griesel R, Zhao Y, Simmons B, Omar Z, Wiesner L,  et al.
2023-05-22 • Lancet HIV
2023-05-22 • Lancet HIV
BACKGROUND
The drug-drug interaction between rifampicin and dolutegravir can be overcome by supplemental dolutegravir dosing, which is difficult to implement in high-burden settings....
Journal Article
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Research

Between empathy and anger: healthcare workers’ perspectives on patient disengagement from antiretroviral treatment in Khayelitsha, South Africa - a qualitative study

Nhemachena T, Späth C, Arendse KD, Lebelo K, Zokufa N,  et al.
2023-01-26 • BMC Primary Care
2023-01-26 • BMC Primary Care
BACKGROUND & OBJECTIVES
The benefits of long-term adherence to antiretroviral therapy (ART) are countered by interruptions in care or disengagement from care. Healthcare workers (HCW...
Journal Article
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Research

A cluster randomized controlled trial of extending ART refill intervals to six-monthly for anti-retroviral adherence clubs

Wilkinson LS, Grimsrud A, Cassidy T, Orrell C, Voget J,  et al.
2019-07-30 • BMC Infectious Diseases
2019-07-30 • BMC Infectious Diseases
BACKGROUND:
The antiretroviral therapy (ART) adherence club (AC) differentiated service delivery model, where clinically stable ART patients receive their ART refills and psychosoci...
Journal Article
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Research

'Only twice a year': a qualitative exploration of 6-month antiretroviral treatment refills in adherence clubs for people living with HIV in Khayelitsha, South Africa

Keene CM, Zokufa N, Venables E, Wilkinson LS, Hoffman R,  et al.
2020-07-08 • BMJ Open
2020-07-08 • BMJ Open
OBJECTIVE
Longer intervals between routine clinic visits and medication refills are part of patient-centred, differentiated service delivery (DSD). They have been shown to improve pa...
Journal Article
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Commentary

How COVID-19 could benefit tuberculosis and HIV services in South Africa

Keene CM, Mohr-Holland E, Cassidy T, Scott V, Nelson AM,  et al.
2020-09-01 • Lancet Respiratory Medicine
2020-09-01 • Lancet Respiratory Medicine
Journal Article
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Research

Twenty‐four‐month outcomes from a cluster‐randomized controlled trial of extending antiretroviral therapy refills in ART adherence clubs

Cassidy T, Grimsrud A, Keene CM, Lebelo K, Hayes H,  et al.
2020-12-01 • Journal of the International AIDS Society
2020-12-01 • Journal of the International AIDS Society
INTRODUCTION
The antiretroviral therapy (ART) adherence club (AC) model has supported clinically stable HIV patients’ retention with group ART refills and psychosocial support. Reduc...