BACKGROUND: Artesunate and amodiaquine (AS&AQ) is at present the world's second most widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the efficacy of...
Bretscher MT, Dahal P, Griffin J, Stepniewska K, Bassat Q, et al.
2020-02-25 • BMC Medicine
2020-02-25 • BMC Medicine
BACKGROUND The majority of Plasmodium falciparum malaria cases in Africa are treated with the artemisinin combination therapies artemether-lumefantrine (AL) and artesunate-amodiaquin...
Dondorp AM, Fanello CI, Hendriksen IC, Gomes E, Seni A, et al.
2010-11-08 • Lancet
2010-11-08 • Lancet
Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established treatment of choice...
Kajungu DK, Erhart A, Talisuna AO, Bassat Q, Karema C, et al.
2014-05-01 • PLOS One
2014-05-01 • PLOS One
Pharmacovigilance programmes monitor and help ensuring the safe use of medicines which is critical to the success of public health programmes. The commonest method used for discovering p...
Zwang J, Ashley EA, Karema C, D'Alessandro U, Smithuis FM, et al.
2009-07-29 • PLOS One
2009-07-29 • PLOS One
BACKGROUND: The fixed dose antimalarial combination of dihydroartemisinin-piperaquine (DP) is a promising new artemisinin-based combination therapy (ACT). We present an individual patien...
