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Copyright © Médecins Sans Frontières
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Showing 1 - 3 of 3 Items
Showing 1 - 3 of 3 Items
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Journal Article
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Research

A standardised phase III clinical trial framework to assess therapeutic interventions for Lassa fever

Olayinka A, Bourner J, Akpede GO, Okoeguale J, Abejegah C,  et al.
2022-01-06 • PLOS Neglected Tropical Diseases
2022-01-06 • PLOS Neglected Tropical Diseases
BACKGROUND
Only one recommendation currently exists for the treatment of Lassa fever (LF), which is ribavirin administered in conjunction with supportive care. This recommendation is...
Journal Article
|
Research

Evaluation of convalescent plasma for Ebola Virus Disease in Guinea

van Griensven J, Edwards T, de Lamballerie X, Semple MG, Gallian P,  et al.
2016-01-07 • New England Journal of Medicine
2016-01-07 • New England Journal of Medicine
BACKGROUND
In the wake of the recent outbreak of Ebola virus disease (EVD) in several African countries, the World Health Organization prioritized the evaluation of treatment with co...
Journal Article
|
Research

Experimental Treatment of Ebola Virus Disease with Brincidofovir

Dunning J, Kennedy SB, Antierens A, Whitehead J, Ciqlenecki I,  et al.
2016-09-09 • PLOS One
2016-09-09 • PLOS One
The nucleotide analogue brincidofovir was developed to prevent and treat infections caused by double-stranded DNA viruses. Based on in vitro data suggesting an antiviral effect against E...