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Copyright © Médecins Sans Frontières
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Showing 1 - 5 of 5 Items
Showing 1 - 5 of 5 Items
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Journal Article
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Research

CD4 count slope and mortality in HIV-infected patients on antiretroviral therapy: multicohort analysis from South Africa

Hoffman CJ, Schomaker M, Fox MP, Mutevedzi, Giddy J,  et al.
2013-01-22 • Journal of Acquired Immune Deficiency Syndromes (1999)
2013-01-22 • Journal of Acquired Immune Deficiency Syndromes (1999)
In many resource-limited settings monitoring of combination antiretroviral therapy (cART) is based on the current CD4 count, with limited access to HIV RNA tests or laboratory diagnostic...
Journal Article
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Research

Life expectancies of South African adults starting antiretroviral treatment: collaborative analysis of cohort studies

Johnson LF, Mossong J, Dorrington R, Schomaker M, Hoffman CJ,  et al.
2013-04-09 • PLOS Medicine
2013-04-09 • PLOS Medicine
Few estimates exist of the life expectancy of HIV-positive adults receiving antiretroviral treatment (ART) in low- and middle-income countries. We aimed to estimate the life expectancy o...
Journal Article
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Research

Risk charts to guide targeted HIV-1 viral load monitoring of ART: development and validation in patients from resource-limited settings

Koller M, Fatti G, Chi BH, Keiser O, Hoffman CJ,  et al.
2015-07-07 • Journal of Acquired Immune Deficiency Syndromes (1999)
2015-07-07 • Journal of Acquired Immune Deficiency Syndromes (1999)
Journal Article
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Research

Mutational correlates of virological failure in individuals receiving a WHO-recommended tenofovir-containing first-line regimen: Aa international collaboration

Rhee SY, Varghese B, Holmes SP, Van Zyl GU, Steegen K,  et al.
2017-03-19 • EBioMedicine
2017-03-19 • EBioMedicine
Tenofovir disoproxil fumarate (TDF) genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF) on a WHO-recommended TDF-cont...
Journal Article
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Research

Zidovudine impairs immunological recovery on first-line antiretroviral therapy: collaborative analysis of cohort studies in southern Africa

Wandeler G, Gsponer T, Mulenga L, Garone DB, Wood R,  et al.
2013-09-01 • AIDS
2013-09-01 • AIDS
OBJECTIVES
Zidovudine (ZDV) is recommended for first-line antiretroviral therapy (ART) in resource-limited settings. ZDV may, however, lead to anemia and impaired immunological respo...