logo
Science Portal
Copyright © Médecins Sans Frontières
v2.1.5569.produseast1
About MSF Science Portal
About
Contact Us
Frequently Asked Questions (FAQs)
Privacy Policy
Terms of Use
Copyright © Médecins Sans Frontières
v2.1.5569.produseast1
Showing 1 - 8 of 8 Items
Showing 1 - 8 of 8 Items
Sort By: Relevance
  • Newest to oldest
  • Oldest to newest
  • Relevance
Journal Article
|
Protocol

Evaluating the diagnostic accuracy of WHO-recommended treatment decision algorithms for childhood tuberculosis using an individual person dataset: a study protocol

Olbrich L, Larsson L, Dodd P, Palmer M, Nguyen MHTN,  et al.
2025-09-17 • BMJ Open
2025-09-17 • BMJ Open

INTRODUCTION

In 2022, the WHO conditionally recommended the use of treatment decision algorithms (TDAs) for treatment decision-making in children <10 years with...

Journal Article
|
Research

Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis

Gunasekera KS, Marcy O, Muñoz J, Lopez-Varela E, Sekadde MP,  et al.
2023-03-13 • Lancet Child and Adolescent Health
2023-03-13 • Lancet Child and Adolescent Health
BACKGROUND
Many children with pulmonary tuberculosis remain undiagnosed and untreated with related high morbidity and mortality. Recent advances in childhood tuberculosis algorithm d...
Journal Article
|
Research

The Epidemiology, Pathogenesis, Transmission, Diagnosis, and Management of Multidrug-Resistant, Extensively Drug-Resistant, and Incurable Tuberculosis

Dheda K, Gumbo T, Maartens G, Dooley KE, McNerney R,  et al.
2017-03-15 • Lancet Respiratory Medicine
2017-03-15 • Lancet Respiratory Medicine
Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis remains out of control in several parts of the world including Africa and Asia. Although tube...
Journal Article
|
Review

New and repurposed drugs for pediatric multidrug-resistant tuberculosis. Practice-based recommendations

Harausz EP, Garcia-Prats AJ, Seddon JA, Schaaf HS, Hesseling AC,  et al.
2016-11-17 • American Journal of Respiratory and Critical Care Medicine
2016-11-17 • American Journal of Respiratory and Critical Care Medicine
It is estimated that 33,000 children develop multidrug-resistant tuberculosis (MDR-TB) each year. In spite of these numbers, children and adolescents have limited access to the new and r...
Journal Article
|
Research

Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis

Harausz EP, Garcia-Prats AJ, Law S, Schaaf HS, Kredo T,  et al.
2018-07-11 • PLOS Medicine
2018-07-11 • PLOS Medicine
An estimated 32,000 children develop multidrug-resistant tuberculosis (MDR-TB; Mycobacterium tuberculosis resistant to isoniazid and rifampin) each year. Little is known about the optima...
Journal Article
|
Review

Towards early inclusion of children in tuberculosis drugs trials: a consensus statement

Nachman S, Ahmed AO, Amanullah F, Becerra M, Botgros R,  et al.
2015-06-01 • Lancet Infectious Diseases
2015-06-01 • Lancet Infectious Diseases
Children younger than 18 years account for a substantial proportion of patients with tuberculosis worldwide. Available treatments for paediatric drug-susceptible and drug-resistant tuber...
Journal Article
|
Commentary

Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an expert panel

Graham SM, Ahmed T, Amanullah F, Browning R, Cardenas V,  et al.
2012-05-15 • Journal of Infectious Diseases
2012-05-15 • Journal of Infectious Diseases
There is a critical need for improved diagnosis of tuberculosis in children, particularly in young children with intrathoracic disease as this represents the most common type of tubercul...
Journal Article
|
Research

Operational challenges in managing Isoniazid Preventive Therapy in child contacts: A high-burden setting perspective

van Wyk SS, Reid AJ, Mandalakas AM, Enarson D, Beyers N,  et al.
2011-07-08 • BMC Public Health
2011-07-08 • BMC Public Health
ABSTRACT: BACKGROUND: The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five years ...