Jindani A, Atwine D, Grint D, Bah B, Adams J, et al.
2023-09-01 • NEJM Evidence
2023-09-01 • NEJM Evidence
BACKGROUND Shorter but effective tuberculosis treatment regimens would be of value to the tuberculosis treatment community. High-dose rifampicin has been associated with more rapid a...
Shroufi A, Govender NP, Meintjes GA, Black JM, Nel J, et al.
2020-06-01 • International Journal of Infectious Diseases
2020-06-01 • International Journal of Infectious Diseases
BACKGROUND Cryptococcal Meningitis (CM) is estimated to cause 181,000 deaths annually; with the majority occurring in Sub Saharan Africa. Flucytosine is recommended by the World Heal...
Kamink SS, Collin SM, Harrison TS, Gatluak F, Mullahzada AW, et al.
2017-10-02 • PLOS Neglected Tropical Diseases
2017-10-02 • PLOS Neglected Tropical Diseases
BACKGROUND South Sudan is one of the most endemic countries for visceral leishmaniasis (VL), and is frequently affected by large epidemics. In resource-limited settings, clinicians r...
Loyse A, Burry J, Cohn J, Ford NP, Chiller T, et al.
2018-10-18 • Lancet Infectious Diseases
2018-10-18 • Lancet Infectious Diseases
In 2018, WHO issued guidelines for the diagnosis, prevention, and management of HIV-related cryptococcal disease. Two strategies are recommended to reduce the high mortality associated w...
Pekelharing JE, Gatluak F, Harrison TS, Maldonado F, Siddiqui MR, et al.
2020-01-24 • PLOS Neglected Tropical Diseases
2020-01-24 • PLOS Neglected Tropical Diseases
INTRODUCTION Visceral leishmaniasis (VL) is endemic in South Sudan, where outbreaks occur frequently. Because of changes in the immune system during pregnancy, pregnant women are con...
Mashau RC, Meiring ST, Quan VC, Nel J, Greene GS, et al.
2022-06-21 • Lancet Infectious Diseases
2022-06-21 • Lancet Infectious Diseases
BACKGROUND Although flucytosine is a key component of WHO-recommended induction treatment for HIV-associated cryptococcal meningitis, this antifungal agent is not widely available in...
Loyse A, Thangaraj H, Easterbrook PJ, Ford NP, Roy M, et al.
2013-05-31 • Lancet Infectious Diseases
2013-05-31 • Lancet Infectious Diseases
Cryptococcal meningitis is the leading cause of adult meningitis in sub-Saharan Africa, and contributes up to 20% of AIDS-related mortality in low-income and middle-income countries ever...
Shroufi A, Chiller T, Jordan A, Denning DW, Harrison TS, et al.
2021-01-01 • Lancet Infectious Diseases
2021-01-01 • Lancet Infectious Diseases
The UNAIDS target to reduce HIV-related death to fewer than 500 000 deaths per year by 2020 will not be met. 1 This statement might not be headline grabbing as this target was never as p...
