logo
Science Portal
Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
About MSF Science Portal
About
Contact Us
Frequently Asked Questions (FAQs)
Privacy Policy
Terms of Use
Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 20 of 31 Items
Showing 1 - 20 of 31 Items
Sort By: Relevance
  • Newest to oldest
  • Oldest to newest
  • Relevance
Journal Article
|
Research

Sequelae following an epidemic of meningococcal meningitis in Niger in 2022

Idrissa AA, Atti S, Wasaulua RK, Kazadi S, Sani O,  et al.
2025-05-22 • PLOS One
2025-05-22 • PLOS One

BACKGROUND

The management of post-meningitis sequelae is a priority in the WHO Roadmap to Defeat Meningitis by 2030. Nonetheless, the prevalence of sequelae in ...

Journal Article
|
Research

Contribution of maternal adherence to the effect of multiple micronutrient supplementation during pregnancy: a systematic review and individual participant data meta-analysis

Smith ER, Gomes F, Adu-Afarwuah S, Aguayo VM, El Arifeen S,  et al.
2025-05-01 • Advances in Nutrition
2025-05-01 • Advances in Nutrition

Multiple micronutrient supplements (MMSs) in pregnancy reduces risk of infant low birthweight (LBW) and improves other maternal and infant outcom...

Journal Article
|
Research

Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial

Schilling WHK, Mukaka M, Callery JJ, Llewelyn MJ, Cruz CV,  et al.
2024-09-12 • PLOS Medicine
2024-09-12 • PLOS Medicine

BACKGROUND

Hydroxychloroquine (HCQ) has proved ineffective in treating patients hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its safety an...

Journal Article
|
Protocol

Gastroenteritis rehydration of children with severe acute malnutrition (GASTROSAM): A phase II randomised controlled trial: Trial protocol

Olupot-Olupot P, Aloroker F, Mpoya A, Mnjalla H, Paasi G,  et al.
2024-01-16 • Wellcome Open Research
2024-01-16 • Wellcome Open Research

BACKGROUND

Chi...

Journal Article
|
Commentary

Reflections on participation in a trial on hydroxychloroquine as prevention for COVID-19 among health workers in Niger

Kabore Y, Vatrinet R, Guindo O, Moussa SH, Schilling WHK,  et al.
2023-09-06 • American Journal of Tropical Medicine and Hygiene
2023-09-06 • American Journal of Tropical Medicine and Hygiene
In 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a rapidly emerging virus causing the coronavirus disease 2019 (COVID-19) pandemic, had no known effective prophylax...
Journal Article
|
Research

Practices and challenges related to antibiotic use in paediatric treatment in hospitals and health centres in Niger and Uganda: a mixed methods study

Mambula G, Nanjebe D, Munene A, Guindo O, Salifou A,  et al.
2023-07-11 • Antimicrobial Resistance and Infection Control
2023-07-11 • Antimicrobial Resistance and Infection Control
BACKGROUND
Antibiotic resistance is a significant public health problem and is responsible for high mortality in children and new-borns. Strengthening the rational use of antibiotics...
Journal Article
|
Research

Faecal carriage of extended-spectrum ß-lactamase-producing Escherichia coli in a remote region of Niger

Jacquier H, Assao B, Chau F, Guindo O, Condamine B,  et al.
2023-06-25 • Journal of Infection
2023-06-25 • Journal of Infection
OBJECTIVE
Whole genome sequencing (WGS) of extended-spectrum ß-lactamase-producing Escherichia coli (ESBL-E. coli) in developing countries is lacking. Here we describe the population...
Conference Material
|
Abstract

Sequelae following an epidemic of meningococcal meningitis in Niger

Idrissa AA, Atti S, Wasaulua RK, Kazadi S, Guindo O,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
INTRODUCTION
MSF supported Niger’s Ministry of Health (MoH) in responding to a serogroup C meningococcal meningitis epidemic in Magaria and Dungass Districts in 2022. WHO’s global ro...
Conference Material
|
Slide Presentation

Sequelae following an epidemic of meningococcal meningitis in Niger

Idrissa AA, Atti S, Wasaulua RK, Kazadi S, Guindo O,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
Journal Article
|
Research

Impact and cost-effectiveness of rotavirus vaccination in Niger: a modelling study evaluating alternative rotavirus vaccines

Debellut F, Tang K, Clark A, Pecenka C, Assao B,  et al.
2022-10-05 • BMJ Open
2022-10-05 • BMJ Open
OBJECTIVES
To evaluate the cost-effectiveness of alternative rotavirus vaccines in Niger, using UNIVAC, a proportionate outcomes model.

SETTING
The study leverages globa...
Journal Article
|
Research

Acceptability and utilization of a lipid-based nutrient supplement formulated for pregnant women in rural Niger: a multi-methods study

Isanaka S, Kodish SR, Mamaty AA, Guindo O, Zeilani M,  et al.
2019-07-01 • BMC Nutrition
2019-07-01 • BMC Nutrition
Background
In food insecure settings, it may be difficult for pregnant women to meet increased nutritional needs through traditional diets. A promising new strategy to fill nutrient...
Journal Article
|
Research

Immunogenicity of an oral rotavirus vaccine administered with prenatal nutritional support in Niger: A cluster randomized clinical trial

Isanaka S, Garba S, Plikaytis BD, McNeal MM, Guindo O,  et al.
2021-08-10 • PLOS Medicine
2021-08-10 • PLOS Medicine
BACKGROUND
Nutritional status may play a role in infant immune development. To identify potential boosters of immunogenicity in low-income countries where oral vaccine efficacy is lo...
Journal Article
|
Research

Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether-lumefantrine for uncomplicated malaria

Chotsiri P, Denoeud-Ndam L, Baudin E, Guindo O, Diawara H,  et al.
2019-06-01 • Clinical Pharmacology & Therapeutics
2019-06-01 • Clinical Pharmacology & Therapeutics
Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub‐Saharan African children and may affect the pharmacology of antimalarial drugs....
Conference Material
|
Video

Introduction: pandemic of COVID-19 in the Sahel

Guindo O
2020-09-24 • Epicentre Scientific Day Paris 2020
2020-09-24 • Epicentre Scientific Day Paris 2020
Journal Article
|
Research

A feasibility study using mid-upper arm circumference as the sole anthropometric criterion for admission and discharge in the outpatient treatment for severe acute malnutrition

Garba S, Salou H, Nackers F, Ayouba A, Guindo O,  et al.
2021-08-12 • BMC Nutrition
2021-08-12 • BMC Nutrition
BACKGROUND
The World Health Organization recommends the use of a weight-for-height Z-score (WHZ) and/or mid-upper arm circumference (MUAC) as anthropometric criteria for the admissio...
Journal Article
|
Research

Investigating persistent measles dynamics in Niger and associations with rainfall

Blake A, Djibo A, Guindo O, Bharti N
2020-08-26 • Journal of the Royal Society Interface
2020-08-26 • Journal of the Royal Society Interface
Measles is a major cause of child mortality in sub-Saharan Africa. Current immunization strategies achieve low coverage in areas where transmission drivers differ substantially from thos...
Journal Article
|
Research

Adherence and population pharmacokinetic properties of amodiaquine when used for Seasonal Malaria Chemoprevention in African children

Ding J, Coldiron ME, Assao B, Guindo O, Blessborn D,  et al.
2019-10-25 • Clinical Pharmacology & Therapeutics
2019-10-25 • Clinical Pharmacology & Therapeutics
Poor adherence to seasonal malaria chemoprevention (SMC) might affect the protective effectiveness of SMC. Here, we evaluated the population pharmacokinetic properties of amodiaquine and...
Journal Article
|
Research

Efficacy of a low-cost, heat-stable oral rotavirus vaccine in Niger

Isanaka S, Guindo O, Langendorf C, Matar Seck A, Plikaytis BD,  et al.
2017-03-23 • New England Journal of Medicine
2017-03-23 • New England Journal of Medicine
BACKGROUND
Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from diarrhea among children younger than 5 years of age worldwide, with a disproportionate eff...
Journal Article
|
Research

Rotavirus vaccine efficacy up to 2 years of age and against diverse circulating rotavirus strains in Niger: Extended follow-up of a randomized controlled trial

Isanaka S, Langendorf C, McNeal MM, Meyer N, Plikaytis BD,  et al.
2021-07-02 • PLOS Medicine
2021-07-02 • PLOS Medicine
BACKGROUND
Rotavirus vaccination is recommended in all countries to reduce the burden of diarrhea-related morbidity and mortality in children. In resource-limited settings, rotavirus...
Journal Article
|
Research

Evaluation of multiple micronutrient supplementation and medium-quantity lipid-based nutrient supplementation in pregnancy on child development in rural Niger: A secondary analysis of a cluster randomized controlled trial

Sudfeld CR, Bliznashka L, Salifou A, Guindo O, Soumana I,  et al.
2022-05-02 • PLOS Medicine
2022-05-02 • PLOS Medicine
BACKGROUND
It is estimated that over 250 million children under 5 years of age in low- and middle-income countries (LMICs) do not reach their full developmental potential. Poor mater...