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Copyright © Médecins Sans Frontières
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Showing 1 - 11 of 11 Items
Showing 1 - 11 of 11 Items
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Journal Article
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Research

Effectiveness of a community-based approach for the investigation and management of children with household tuberculosis contact in Cameroon and Uganda: a cluster-randomised trial

Bonnet MMB, Vasiliu A, Tchounga BK, Cuer B, Fielding K,  et al.
2023-10-30 • Lancet Global Health
2023-10-30 • Lancet Global Health
BACKGROUND
Globally, the uptake of tuberculosis-preventive treatment (TPT) among children with household tuberculosis contact remains low, partly due to the necessity of bringing chi...
Journal Article
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Research

Clinical standards for drug-susceptible TB in children and adolescents

Chiang SS, Graham SM, Schaaf HS, Marais BJ, Sant’Anna CC,  et al.
2023-08-01 • International Journal of Tuberculosis and Lung Disease
2023-08-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
These clinical standards aim to provide guidance for diagnosis, treatment, and management of drug-susceptible TB in children and adolescents.

METHODS
Fifty-tw...
Journal Article
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Research

Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis

Gunasekera KS, Marcy O, Muñoz J, Lopez-Varela E, Sekadde MP,  et al.
2023-03-13 • Lancet Child and Adolescent Health
2023-03-13 • Lancet Child and Adolescent Health
BACKGROUND
Many children with pulmonary tuberculosis remain undiagnosed and untreated with related high morbidity and mortality. Recent advances in childhood tuberculosis algorithm d...
Journal Article
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Research

Effect of systematic tuberculosis detection on mortality in young children with severe pneumonia in countries with high incidence of tuberculosis: a stepped-wedge cluster-randomised trial

Marcy O, Wobudeya E, Font H, Vessière A, Chabala C,  et al.
2023-03-01 • Lancet Infectious Diseases
2023-03-01 • Lancet Infectious Diseases
BACKGROUND
Tuberculosis diagnosis might be delayed or missed in children with severe pneumonia because this diagnosis is usually only considered in cases of prolonged symptoms or ant...
Journal Article
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Review

New and repurposed drugs for pediatric multidrug-resistant tuberculosis. Practice-based recommendations

Harausz EP, Garcia-Prats AJ, Seddon JA, Schaaf HS, Hesseling AC,  et al.
2016-11-17 • American Journal of Respiratory and Critical Care Medicine
2016-11-17 • American Journal of Respiratory and Critical Care Medicine
It is estimated that 33,000 children develop multidrug-resistant tuberculosis (MDR-TB) each year. In spite of these numbers, children and adolescents have limited access to the new and r...
Journal Article
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Research

Clinical standards for the diagnosis, treatment and prevention of TB infection

Migliori GB, Wu SJ, Matteelli A, Zenner D, Goletti D,  et al.
2022-03-01 • International Journal of Tuberculosis and Lung Disease
2022-03-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
Tuberculosis (TB) preventive therapy (TPT) decreases the risk of developing TB disease and its associated morbidity and mortality. The aim of these clinical standards is t...
Conference Material
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Poster

Management practices for pneumonia: a mixed-methods survey

Hinh J, Chan G, du Cros PAK, Walker SA, Graham SM,  et al.
2022-05-09 • MSF Scientific Days International 2022
2022-05-09 • MSF Scientific Days International 2022
Journal Article
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Commentary

Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an expert panel

Graham SM, Ahmed T, Amanullah F, Browning R, Cardenas V,  et al.
2012-05-15 • Journal of Infectious Diseases
2012-05-15 • Journal of Infectious Diseases
There is a critical need for improved diagnosis of tuberculosis in children, particularly in young children with intrathoracic disease as this represents the most common type of tubercul...
Journal Article
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Research

The trend of tuberculosis cases over 60 years in Fiji's largest treatment centre: 1950-2010

Tamani T, Bissell K, Tayler-Smith K, Gounder S, Linh NN,  et al.
2014-03-21 • Public Health Action
2014-03-21 • Public Health Action
SETTING
P J Twomey Hospital, National Tuberculosis Programme, Fiji.

OBJECTIVES
To review the trend in numbers of tuberculosis (TB) cases registered each year from 1950 t...
Journal Article
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Research

Passive Versus Active Tuberculosis Case Finding and Isoniazid Preventive Therapy Among Household Contacts in a Rural District of Malawi

Zachariah R, Spielmann M P, Harries AD, Gomani P, Graham SM,  et al.
2003-11-01 • International Journal of Tuberculosis and Lung Disease
2003-11-01 • International Journal of Tuberculosis and Lung Disease
SETTING: Thyolo district, rural Malawi. OBJECTIVES: To compare passive with active case finding among household contacts of smear-positive pulmonary tuberculosis (TB) patients for 1) TB ...
Journal Article
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Research

Scaling-up co-trimoxazole prophylaxis in HIV-exposed and HIV-infected children in high HIV-prevalence countries

Zachariah R, Harries AD, Luo C, Bachman G, Graham SM
2007-10-01 • Lancet Infectious Diseases
2007-10-01 • Lancet Infectious Diseases
Co-trimoxazole (trimethoprim-sulfamethoxazole) is a widely available antibiotic that substantially reduces HIV-related morbidity and mortality in both adults and children. Prophylaxis wi...