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Showing 1 - 3 of 3 Items
Showing 1 - 3 of 3 Items
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Journal Article
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Research

Real-Time PCR for the Evaluation of Treatment Response in Clinical Trials of Adult Chronic Chagas Disease: Usefulness of Serial Blood Sampling and qPCR Replicates

Parrado R, Ramirez JC, de la Barra A, Alonso-Vega C, Juiz N,  et al.
2018-12-03 • Antimicrobial Agents and Chemotherapy
2018-12-03 • Antimicrobial Agents and Chemotherapy
This work evaluated a serial blood sampling procedure to enhance the sensitivity of duplex real-time PCR (qPCR) for baseline detection and quantification of parasitic loads and post-trea...
Journal Article
|
Research

First external Quality Assurance Program for bloodstream Real-Time PCR monitoring of treatment response in clinical trials of Chagas disease

Ramirez JC, Parrado R, Sulleiro E, de la Barra A, Rodriguez M,  et al.
2017-11-27 • PLOS One
2017-11-27 • PLOS One
Real-Time PCR (qPCR) testing is recommended as both a diagnostic and outcome measurement of etiological treatment in clinical practice and clinical trials of Chagas disease (CD), but no ...
Journal Article
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Research

Control of mucocutaneous leishmaniasis, a neglected disease: results of a control programme in Satipo Province, Peru

Guthmann JP, Arlt D, Garcia LML, Rosales M, Jesus Sanchez J,  et al.
2005-09-01 • Tropical Medicine and International Health
2005-09-01 • Tropical Medicine and International Health
Mucocutaneous leishmaniasis (MCL) is an important health problem in many rural areas of Latin America, but there are few data on the results of programmatic approaches to control the dis...