Olayinka A, Bourner J, Akpede GO, Okoeguale J, Abejegah C, et al.
2022-01-06 • PLOS Neglected Tropical Diseases
2022-01-06 • PLOS Neglected Tropical Diseases
BACKGROUND Only one recommendation currently exists for the treatment of Lassa fever (LF), which is ribavirin administered in conjunction with supportive care. This recommendation is...
Cnops L, van Griensven J, Honko AN, Bausch DG, Sprecher A, et al.
2016-06-10 • Lancet Infectious Diseases
2016-06-10 • Lancet Infectious Diseases
Quantitative measurement of viral load is an important parameter in the management of filovirus disease outbreaks because viral load correlates with severity of disease, survival, and in...
Grolla A, Jones SM, Fernando L, Strong JE, Stroher U, et al.
2011-05-24 • PLOS Neglected Tropical Diseases
2011-05-24 • PLOS Neglected Tropical Diseases
Background: Marburg virus (MARV), a zoonotic pathogen causing severe hemorrhagic fever in man, has emerged in Angola resulting in the largest outbreak of Marburg hemorrhagic fever (MHF) ...
Nguku PM, Sharif S, Omar A, Nzioka C, Muthoka P, et al.
2007-02-02 • MMWR. Morbidity and mortality weekly report
2007-02-02 • MMWR. Morbidity and mortality weekly report
In mid-December 2006, several unexplained fatalities associated with fever and generalized bleeding were reported to the Kenya Ministry of Health (KMOH) from Garissa District in North Ea...
Wong G, Qiu X, Bi Y, Formenty P, Sprecher A, et al.
2016-10-15 • Journal of Infectious Diseases
2016-10-15 • Journal of Infectious Diseases
Cases of relapsed Ebola virus disease involving symptoms in the central nervous system are reminiscent of our past observations with some nonhuman primates (NHPs) that survived acute Ebo...
Nsio JM, Kapteshi K, Makiala S, Raymond F, Tshapenda G, et al.
2019-04-03 • Journal of Infectious Diseases
2019-04-03 • Journal of Infectious Diseases
BACKGROUND In 2017, the Democratic Republic of the Congo (DRC) recorded its eighth Ebola virus disease (EVD) outbreak, approximately 3 years after the previous outbreak.
Ruibal P, Oestereich L, Ludtke A, Becker-Ziaja B, Wozniak DM, et al.
2016-05-04 • Nature
2016-05-04 • Nature
Despite the magnitude of the Ebola virus disease (EVD) outbreak in West Africa, there is still a fundamental lack of knowledge about the pathophysiology of EVD. In particular, very littl...
Adjemian J, Farnon EC, Tschioko F, Wamala JF, Byaruhanga E, et al.
2011-11-01 • Journal of Infectious Diseases
2011-11-01 • Journal of Infectious Diseases
Marburg hemorrhagic fever was detected among 4 miners in Ibanda District, Uganda, from June through September, 2007. Infection was likely acquired through exposure to bats or bat secreti...
Strecker T, Palyi B, Ellerbrok H, Jonckheere S, De Clerck H, et al.
2015-05-19 • Clinical Infectious Diseases
2015-05-19 • Clinical Infectious Diseases
Reliable reverse-transcriptase polymerase chain reaction (RT-PCR)-based diagnosis of Ebola virus infection currently requires a blood sample obtained by intravenous puncture. During the ...
In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. ...
Osterholm M, Moore K, Kelley N, Brosseau L, Wong G, et al.
2015-02-19 • mBio
2015-02-19 • mBio
Available evidence demonstrates that direct patient contact and contact with infectious body fluids are the primary modes for Ebola virus transmission, but this is based on a limited num...
