Ndlovu Z, Massaquoi L, Bangwen NE, Batumba JN, Bora RU, et al.
2020-04-03 • PLOS One
2020-04-03 • PLOS One
BACKGROUND In sub-Saharan Africa, a third of people starting antiretroviral therapy and majority of patients returning to HIV-care after disengagement, present with advanced HIV dise...
Ardizzoni E, Fajardo E, Saranchuk P, Casenghi M, Page AL, et al.
2015-12-15 • PLOS One
2015-12-15 • PLOS One
BACKGROUND The Xpert® MTB/RIF (Xpert) is an automated molecular test for simultaneous detection of tuberculosis (TB) and rifampicin resistance, recommended by the World Health Organi...
Fajardo E, Metcalf CJ, Piriou E, Gueguen M, Maman D, et al.
2015-06-25 • Bulletin of the World Health Organization
2015-06-25 • Bulletin of the World Health Organization
OBJECTIVE To estimate the proportion of invalid results generated by a CD4+ T-lymphocyte analyser used by Médecins Sans Frontières (MSF) in field projects and identify factors associ...
Mpala Q, Maphalala G, Uribe PAD, de la Tour R, Kalombola S, et al.
2018-11-14 • BMC Infectious Diseases
2018-11-14 • BMC Infectious Diseases
Viral load (VL) testing is being scaled up in resource-limited settings. However, not all commercially available VL testing methods have been evaluated under field conditions. This study...
Kerschberger B, Ntshalintshali N, Mpala Q, Diaz Uribe PA, Maphalala G, et al.
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND To assess the performance and suitability of dried blood spot (DBS) sampling using filter paper to collect blood for viral load (VL) quantification under routine condition...
2012-10-09 • Journal of the International AIDS Society
2012-10-09 • Journal of the International AIDS Society
Though the advantages of routine virological monitoring for patients on anti-retroviral therapy have been established, cost and complexity limit its full implementation. Monitoring is im...
Pannus P, Fajardo E, Metcalf CJ, Coulborn R M, Duran LT, et al.
2013-07-25 • Journal of Acquired Immune Deficiency Syndromes (1999)
2013-07-25 • Journal of Acquired Immune Deficiency Syndromes (1999)
: Rollout of routine HIV-1 viral load monitoring is hampered by high costs and logistical difficulties associated with sample collection and transport. New strategies are needed to overc...
Ndlovu M, Fajardo E, Mbofana F, Maparo TMS, Garone DB, et al.
2018-03-02 • PLOS One
2018-03-02 • PLOS One
HIV Viral Load and Early Infant Diagnosis technologies in many high burden settings are restricted to centralized laboratory testing, leading to long result turnaround times and patient ...
The World Health Organization (WHO) currently recommends Xpert® MTB/RIF as the initial test for all people with presumptive tuberculosis (TB). A number of challenges have been reported, ...
Bonner K, Siemieniuk R, Boozary A, Roberts TR, Fajardo E, et al.
2014-12-01 • PLOS One
2014-12-01 • PLOS One
HIV viral load (VL) testing is the gold standard for antiretroviral treatment monitoring, but many barriers exist to VL testing in resource-limited settings, including storage and transp...
Fajardo E, Metcalf CJ, Mbofana F, van Vyve C, Munyaradzi D, et al.
2014-10-22 • BMC Infectious Diseases
2014-10-22 • BMC Infectious Diseases
BackgroundCD4+ T-cell testing of blood specimens collected in standard EDTA Vacutainer tubes and transported at ambient temperature, must be completed within 48 hours with the BD FACSCou...