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v2.1.5153.produseast1
Showing 1 - 6 of 6 Items
Showing 1 - 6 of 6 Items
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Journal Article
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Research

Efficacy of artesunate-amodiaquine, dihydroartemisinin-piperaquine and artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Maradi, Niger

Grandesso F, Guindo O, Woi-Messe LC, Makarimi R, Traore A,  et al.
2018-01-25 • Malaria Journal
2018-01-25 • Malaria Journal
BACKGROUND
Malaria endemic countries need to assess efficacy of anti-malarial treatments on a regular basis. Moreover, resistance to artemisinin that is established across mainland S...
Journal Article
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Research

Seasonal malaria chemoprevention with sulphadoxine-pyrimethamine and amodiaquine selects pfdhfr-dhps quintuple mutant genotype in Mali

Maiga H, Lasry E, Diarra M, Sagara I, Bamadio A,  et al.
2016-09-23 • PLOS One
2016-09-23 • PLOS One
BACKGROUND
Seasonal malaria chemoprevention (SMC) with sulphadoxine-pyrimethamine (SP) plus amodiaquine (AQ) is being scaled up in Sahelian countries of West Africa. However, the pot...
Journal Article
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Research

Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis

WorldWide Antimalarial Resistance Network Methodology Study Group, Dahal P, Simpson JA, Abdulla S, Achan J,  et al.
2019-07-05 • Malaria Journal
2019-07-05 • Malaria Journal
BACKGROUND
Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potenti...
Protocol
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Research Protocol

A multi-center, open-label trial to compare the efficacy and pharmacokinetics of Artemether-Lumefantrine in children with severe acute malnutrition versus children without severe acute malnutrition: study protocol for the MAL-NUT study

Denoeud-Ndam L, Dicko A, Baudin E, Guindo O, Grandesso F,  et al.
2015-06-12 • BMC Infectious Diseases
2015-06-12 • BMC Infectious Diseases
Malnutrition and malaria frequently coexist in sub-Saharan African countries. Studies on efficacy of antimalarial treatments usually follow the WHO standardized protocol in which severel...
Journal Article
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Research

Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali

De Radiguès X, Diallo KI, Diallo MO, Ngwakum PA, Maiga H,  et al.
2006-11-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2006-11-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
We report the results of an in vivo antimalarial efficacy study with chloroquine (CQ) and sulfadoxine/pyrimethamine (SP) conducted between 2003 and 2004 in Koumantou, southern Mali. A to...
Journal Article
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Research

Two-year scale-up of seasonal malaria chemoprevention reduced malaria morbidity among children in the health district of Koutiala, Mali

Maiga H, Gaudart J, Sagara I, Diarra M, Bamadio A,  et al.
2020-09-11 • International Journal of Environmental Research and Public Health
2020-09-11 • International Journal of Environmental Research and Public Health
BACKGROUND
Previous controlled studies demonstrated seasonal malaria chemoprevention (SMC) reduces malaria morbidity by >80% in children aged 3-59 months. Here, we assessed malaria m...