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Showing 1 - 20 of 24 Items
Showing 1 - 20 of 24 Items
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Journal Article
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Short Report

Explaining seasonal fluctuations of measles in Niger using nighttime lights imagery

Bharti N, Tatem AJ, Ferrari MJ, Grais RF, Djibo A,  et al.
2011-12-09 • Science
2011-12-09 • Science
Measles epidemics in West Africa cause a significant proportion of vaccine-preventable childhood mortality. Epidemics are strongly seasonal, but the drivers of these fluctuations are poo...
Journal Article
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Research

Spatial dynamics of meningococcal meningitis in Niger: observed patterns in comparison with measles

Bharti N, Broutin H, Grais RF, Ferrari MJ, Djibo A,  et al.
2011-10-05 • Epidemiology and Infection
2011-10-05 • Epidemiology and Infection
Throughout the African meningitis belt, meningococcal meningitis outbreaks occur only during the dry season. Measles in Niger exhibits similar seasonality, where increased population den...
Journal Article
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Research

Rural-urban gradient in seasonal forcing of measles transmission in Niger

Ferrari MJ, Djibo A, Grais RF, Bharti N, Grenfell BT,  et al.
2010-09-22 • Proceedings. Biological sciences / The Royal Society
2010-09-22 • Proceedings. Biological sciences / The Royal Society
Seasonally driven cycles of incidence have been consistently observed for a range of directly transmitted pathogens. Though frequently observed, the mechanism of seasonality for directly...
Journal Article
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Research

Ceftriaxone as effective as long-acting chloramphenicol in short-course treatment of meningococcal meningitis during epidemics: a randomised non-inferiority study

Nathan N, Borel T, Djibo A, Evans D, Djibo S,  et al.
2008-04-14 • Lancet
2008-04-14 • Lancet
BACKGROUND: In sub-Saharan Africa in the 1990s, more than 600,000 people had epidemic meningococcal meningitis, of whom 10% died. The current recommended treatment by WHO is short-course...
Journal Article
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Research

Evaluation and use of surveillance system data toward the identification of high-risk areas for potential cholera vaccination: a case study from Niger

Guerra J, Mayana B, Djibo A, Manzo ML, Augusto E,  et al.
2012-05-14 • BMC Research Notes
2012-05-14 • BMC Research Notes
In 2008, Africa accounted for 94% of the cholera cases reported worldwide. Although the World Health Organization currently recommends the oral cholera vaccine in endemic areas for high-...
Journal Article
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Research

Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012

Page AL, Jusot V, Mamaty AA, Adamou L, Kaplon J,  et al.
2014-04-01 • Emerging Infectious Diseases
2014-04-01 • Emerging Infectious Diseases
Knowledge of rotavirus epidemiology is necessary to make informed decisions about vaccine introduction and to evaluate vaccine impact. During April 2010–March 2012, rotavirus surveillanc...
Journal Article
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Research

Mortality risk among children admitted in a large-scale nutritional program in Niger, 2006

Lapidus N, Minetti A, Djibo A, Guerin JP, Hustache S,  et al.
2009-01-29 • PLOS One
2009-01-29 • PLOS One
BACKGROUND
In 2006, the Médecins sans Frontières nutritional program in the region of Maradi (Niger) included 68,001 children 6-59 months of age with either moderate or severe malnut...
Journal Article
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Research

Investigating persistent measles dynamics in Niger and associations with rainfall

Blake A, Djibo A, Guindo O, Bharti N
2020-08-26 • Journal of the Royal Society Interface
2020-08-26 • Journal of the Royal Society Interface
Measles is a major cause of child mortality in sub-Saharan Africa. Current immunization strategies achieve low coverage in areas where transmission drivers differ substantially from thos...
Journal Article
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Research

Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial

Isanaka S, Nombela N, Djibo A, Poupard M, Van Beckhoven D,  et al.
2009-01-21 • Journal of the American Medical Association (JAMA)
2009-01-21 • Journal of the American Medical Association (JAMA)
CONTEXT
Ready-to-use therapeutic foods (RUTFs) are an important component of effective outpatient treatment of severe wasting. However, their effectiveness in the population-based pr...
Journal Article
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Research

Efficacy of a low-cost, heat-stable oral rotavirus vaccine in Niger

Isanaka S, Guindo O, Langendorf C, Matar Seck A, Plikaytis BD,  et al.
2017-03-23 • New England Journal of Medicine
2017-03-23 • New England Journal of Medicine
BACKGROUND
Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from diarrhea among children younger than 5 years of age worldwide, with a disproportionate eff...
Journal Article
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Research

High sensitivity and specificity of the Pastorex latex agglutination test for Neisseria meningitidis serogroup A during a clinical trial in Niger

Borel T, Rose AMC, Guillerm M, Sidikou F, Gerstl S,  et al.
2006-10-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2006-10-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
There is a great need for a rapid diagnostic test to guide vaccine choice during outbreaks of meningococcal meningitis in resource-poor countries. During a randomised clinical trial cond...
Journal Article
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Research

Estimating transmission intensity for a measles epidemic in Niamey, Niger: lessons for intervention

Grais RF, Ferrari MJ, Dubray C, Bjørnstad ON, Grenfell BT,  et al.
2006-09-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2006-09-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
The objective of this study is to estimate the effective reproductive ratio for the 2003-2004 measles epidemic in Niamey, Niger. Using the results of a retrospective and prospective stud...
Journal Article
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Research

Unacceptably high mortality related to measles epidemics in Niger, Nigeria, and Chad

Grais RF, Dubray C, Gerstl S, Guthmann JP, Djibo A,  et al.
2007-01-01 • PLOS Medicine
2007-01-01 • PLOS Medicine
BACKGROUND: Despite the comprehensive World Health Organization (WHO)/United Nations Children's Fund (UNICEF) measles mortality-reduction strategy and the Measles Initiative, a partnersh...
Journal Article
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Research

Time is of the essence: exploring a measles outbreak response vaccination in Niamey, Niger

Grais RF, Conlan AJK, Ferrari MJ, Djibo A, Le Menach A,  et al.
2008-01-06 • Journal of the Royal Society Interface
2008-01-06 • Journal of the Royal Society Interface
The current World Health Organization recommendations for response during measles epidemics focus on case management rather than outbreak response vaccination (ORV) campaigns, which may ...
Journal Article
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Review

Case-Fatality Rates and Sequelae Resulting from Neisseria Meningitidis Serogroup C Epidemic, Niger, 2015

Coldiron ME, Salou H, Sidikou F, Goumbi K, Djibo A,  et al.
2016-10-01 • Emerging Infectious Diseases
2016-10-01 • Emerging Infectious Diseases
We describe clinical symptoms, case-fatality rates, and prevalence of sequelae during an outbreak of Neisseria meningitidis serogroup C infection in a rural district of Niger. During hom...
Journal Article
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Research

Measles hotspots and epidemiological connectivity

Bharti N, Djibo A, Tatem AJ, McCabe CA, Bjørnstad ON,  et al.
2010-09-01 • Epidemiology and Infection
2010-09-01 • Epidemiology and Infection
Though largely controlled in developed countries, measles remains a major global public health issue. Regional and local transmission patterns are rooted in human mixing behaviour across...
Journal Article
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Research

The dynamics of measles in sub-Saharan Africa

Ferrari MJ, Grais RF, Bharti N, Conlan AJK, Bjørnstad ON,  et al.
2008-02-07 • Nature
2008-02-07 • Nature
Although vaccination has almost eliminated measles in parts of the world, the disease remains a major killer in some high birth rate countries of the Sahel. On the basis of measles dynam...
Journal Article
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Research

Effectiveness of ready-to-use therapeutic food compared to a corn/soy-blend-based pre-mix for the treatment of childhood moderate acute malnutrition in Niger

Nackers F, Broillet F, Oumarou D, Djibo A, Gaboulaud V,  et al.
2010-10-01 • Journal of Tropical Pediatrics
2010-10-01 • Journal of Tropical Pediatrics
Standard nutritional treatment of moderate acute malnutrition (MAM) relies on fortified blended flours though their importance to treat this condition is a matter of discussion. With the...
Journal Article
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Research

Long-acting chloramphenicol versus intravenous ampicillin for treatment of bacterial meningitis

Pécoul B, Varaine FFV, Keita M, Soga G, Djibo A,  et al.
1991-10-05 • Lancet
1991-10-05 • Lancet
In most developing countries, bacterial meningitis (BM) is associated with a high case-fatality rate. The search for a simple, convenient, and inexpensive antibiotic treatment remains a ...
Journal Article
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Research

Modelling the first dose of measles vaccination: the role of maternal immunity, demographic factors, and delivery systems

Metcalf CJ, Klepac P, Ferrari MJ, Grais RF, Djibo A,  et al.
2010-06-01 • Epidemiology and Infection
2010-06-01 • Epidemiology and Infection
Measles vaccine efficacy is higher at 12 months than 9 months because of maternal immunity, but delaying vaccination exposes the children most vulnerable to measles mortality to infectio...