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Copyright © Médecins Sans Frontières
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Showing 1 - 13 of 13 Items
Showing 1 - 13 of 13 Items
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Journal Article
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Research

Diagnostic accuracy of tuberculin skin test self-reading by HIV patients in a low-resource setting

Cox V, De Azevedo V, Stinson K, Wilkinson LS, Rangaka MX,  et al.
2015-11-01 • International Journal of Tuberculosis and Lung Disease
2015-11-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
The World Health Organization recommends tuberculin skin tests (TSTs) where feasible to identify individuals most likely to benefit from isoniazid preventive therapy (IPT)...
Journal Article
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Research

Attrition from HIV care among youth initiating ART in youth-only clinics compared with general primary healthcare clinics in Khayelitsha, South Africa: a matched propensity score analysis

Cassidy T, Cornell M, Runeyi P, Dutyulwa T, Kilani C,  et al.
2022-01-25 • Journal of the International AIDS Society
2022-01-25 • Journal of the International AIDS Society
INTRODUCTION
Youth living with HIV (YLWH) are less likely to initiate antiretroviral therapy (ART) and remain in care than older adults. It is important to identify effective strate...
Journal Article
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Research

Time to ART initiation among patients treated for rifampin-resistant tuberculosis in Khayelitsha, South Africa: Impact on mortality and treatment success

Daniels J, Khogali MA, Mohr E, Cox V, Moyo S,  et al.
2015-11-10 • PLOS One
2015-11-10 • PLOS One
SETTING
Khayelitsha, South Africa, with high burdens of rifampicin-resistant tuberculosis (RR-TB) and HIV co-infection.

OBJECTIVE
To describe time to antiretroviral trea...
Journal Article
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Research

Clinical mentorship of nurse initiated antiretroviral therapy in Khayelitsha, South Africa: a quality of care assessment

Green A, De Azevedo V, Patten GE, Davies MA, Ibeto M,  et al.
2014-06-02 • PLOS One
2014-06-02 • PLOS One
To combat the AIDS epidemic and increase HIV treatment access, the South African government implemented a nurse-based, doctor-supported model of care that decentralizes administration of...
Journal Article
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Research

Impact on ART initiation of point-of-care CD4 testing at HIV diagnosis among HIV-positive youth in Khayelitsha, South Africa

Patten GE, Wilkinson LS, Conradie K, Isaakidis P, Harries AD,  et al.
2013-07-04 • Journal of the International AIDS Society
2013-07-04 • Journal of the International AIDS Society
Despite the rapid expansion of antiretroviral therapy (ART) programmes in developing countries, pre-treatment losses from care remain a challenge to improving access to treatment. Youth ...
Journal Article
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Research

"Life continues": Patient, health care and community care workers perspectives on self-administered treatment for rifampicin-resistant tuberculosis in Khayelitsha, South Africa

Mohr E, Snyman L, Mbakaz Z, Caldwell J, De Azevedo V,  et al.
2018-09-14 • PLOS One
2018-09-14 • PLOS One
BACKGROUND
Self-administered treatment (SAT), a differentiated model of care for rifampicin-resistant tuberculosis (RR-TB), might address adherence challenges faced by patients and h...
Journal Article
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Research

DOT or SAT for Rifampicin-resistant tuberculosis? A non-randomized comparison in a high HIV-prevalence setting

Mohr E, Daniels J, Beko B, Isaakidis P, Cox V,  et al.
2017-05-18 • PLOS One
2017-05-18 • PLOS One
BACKGROUND
Daily directly-observed therapy (DOT) is recommended for rifampicin-resistant tuberculosis (RR-TB) patients throughout treatment. We assessed the impact of self-administer...
Journal Article
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Letter

Bedaquiline and delamanid in combination for treatment of drug-resistant tuberculosis

Mohr E, Ferlazzo G, Hewison CCH, De Azevedo V, Isaakidis P
2019-05-01 • Lancet Infectious Diseases
2019-05-01 • Lancet Infectious Diseases
Here we report on the final outcomes for the cohort of 28 patients from Armenia, India, and South Africa who initiated regimens containing the combination of bedaquiline and delamanid fr...
Journal Article
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Research

Injectable-free regimens containing bedaquiline, delamanid, or both for adolescents with rifampicin-resistant tuberculosis in Khayelitsha, South Africa

Mohr-Holland E, Reuter A, Furin J, Garcia-Prats AJ, De Azevedo V,  et al.
2020-03-01 • eClinicalMedicine
2020-03-01 • eClinicalMedicine
BACKGROUND
Limited data exist on the use of bedaquiline and delamanid in adolescents with rifampicin-resistant tuberculosis (RR-TB). We describe RR-TB treatment of adolescents (10-19...
Journal Article
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Research

Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa

Mohr E, Hughes J, Reuter A, Trivino Duran L, Ferlazzo G,  et al.
2018-05-03 • European Respiratory Journal
2018-05-03 • European Respiratory Journal
Experience with delamanid (Dlm) is limited, particularly among HIV-positive individuals. We describe early efficacy and safety data from a programmatic setting in South Africa. This was ...
Journal Article
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Research

Knowledge transmission, peer support, behaviour change and satisfaction in post Natal clubs in Khayelitsha, South Africa: a qualitative study

Duvivier H, Decroo T, Nelson AM, Cassidy T, Mbakaz Z,  et al.
2020-07-08 • Reproductive Health
2020-07-08 • Reproductive Health
Background
The Post Natal Club (PNC) model assures comprehensive care, including HIV and Maternal and Child Health care, for postpartum women living with HIV and their infants durin...
Journal Article
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Research

Loss from treatment for drug resistant tuberculosis: risk factors and patient outcomes in a community-based program in Khayelitsha, South Africa

Moyo S, Cox HS, Hughes J, Daniels J, Synman L,  et al.
2015-03-18 • PLOS One
2015-03-18 • PLOS One
A community based drug resistant tuberculosis (DR-TB) program has been incrementally implemented in Khayelitsha, a high HIV and TB burden community in South Africa. We investigated loss ...
Journal Article
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Commentary

Barriers and solutions to finding rifampicin-resistant tuberculosis cases in older children and adolescents

Mohr-Holland E, Apolisi I, Reuter A, De Azevedo V, Hill JE,  et al.
2019-12-21 • Public Health Action
2019-12-21 • Public Health Action
Little is known about the barriers to post-exposure management of rifampicin-resistant tuberculosis (RR-TB) in older children and adolescents. We report on implementation lessons from a ...