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Showing 1 - 12 of 12 Items
Showing 1 - 12 of 12 Items
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Research

Risk stratification of childhood infection using host markers of immune and endothelial activation in Asia (Spot Sepsis): a multi-country, prospective, cohort study

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Van Anh DT,  et al.
2025-09-01 • Lancet Child and Adolescent Health
2025-09-01 • Lancet Child and Adolescent Health

BACKGROUND

Prognostic tools for febrile illnesses are urgently required in resource-constrained community contexts. Circulating immune and endothelial activatio...

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Video

Facilitating safe discharge through predicting disease progression in moderate Covid-19: development and validation of a prediction model in resource-limited settings

Chandna A
2022-06-07 • MSF Scientific Days International 2022
2022-06-07 • MSF Scientific Days International 2022

Derivation and validation of prognostic models for the risk stratification of childhood infection: a multi-country prospective cohort study in Asia (Spot-Sepsis)

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Anh DTV,  et al.
2025-02-05 • MSF Scientific Days International 2025
2025-02-05 • MSF Scientific Days International 2025

Derivation and validation of prognostic models for the risk stratification of childhood infection: a multi-country prospective cohort study in Asia (Spot-Sepsis)

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Anh DTV,  et al.
2025-02-05 • MSF Scientific Days International 2025
2025-02-05 • MSF Scientific Days International 2025

Risk stratification of childhood infection using host markers of immune and endothelial activation: A multi-country prospective cohort study in Asia (Spot Sepsis)

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Anh DTV,  et al.
2025-02-05 • medRxiv
2025-02-05 • medRxiv

BACKGROUND

Circulating markers of immune and endothelial activation risk stratify infection syndromes agnostic to disease aetiology. However, their utility in c...

Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial

Schilling WHK, Mukaka M, Callery JJ, Llewelyn MJ, Cruz CV,  et al.
2024-09-12 • PLOS Medicine
2024-09-12 • PLOS Medicine

BACKGROUND

Hydroxychloroquine (HCQ) has proved ineffective in treating patients hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its safety an...

Point-of-care prognostication in moderate Covid-19: Analytical validation and prognostic accuracy of a soluble urokinase plasminogen activator receptor (suPAR) rapid test

Chandna A, Mahajan R, Gautam P, Mwandigha L, Dittrich S,  et al.
2023-08-21 • PLOS Global Public Health
2023-08-21 • PLOS Global Public Health
The soluble urokinase plasminogen activator receptor (suPAR) has been proposed as a biomarker for risk stratification of patients presenting with acute infections. However, most studies ...

Facilitating safe discharge through predicting disease progression in moderate COVID-19: development and validation of a prediction model in resource-limited settings

Chandna A, PRIORITISE Study Group, Mahajan R, Gautam P, Mwandigha L,  et al.
2022-05-09 • MSF Scientific Days International 2022
2022-05-09 • MSF Scientific Days International 2022
INTRODUCTION
In locations where few people have received Covid-19 vaccines, health systems remain vulnerable to spikes in SARS-CoV-2 infections. Triage tools, which could include bio...

Facilitating safe discharge through predicting disease progression in moderate COVID-19: a prospective cohort study to develop and validate a clinical prediction model in resource-limited settings

Chandna A, Mahajan R, Gautam P, Mwandigha L, Gunasekaran K,  et al.
2022-03-21 • Clinical Infectious Diseases
2022-03-21 • Clinical Infectious Diseases
BACKGROUND
In locations where few people have received COVID-19 vaccines, health systems remain vulnerable to surges in SARS-CoV-2 infections. Tools to identify patients suitable for...

Prediction of disease severity in young children presenting with acute febrile illness in resource-limited settings: a protocol for a prospective observational study

Chandna A, Aderie EM, Ahmad R, Arguni E, Ashley EA,  et al.
2021-01-25 • BMJ Open
2021-01-25 • BMJ Open
INTRODUCTION
In rural and difficult-to-access settings, early and accurate recognition of febrile children at risk of progressing to serious illness could contribute to improved pati...

Facilitating safe discharge through predicting disease progression in moderate Covid-19: development and validation of a prediction model in resource-limited settings

Chandna A, PRIORITISE Study Group, Mahajan R, Gautam P, Mwandigha L,  et al.
2022-05-10 • MSF Scientific Days International 2022
2022-05-10 • MSF Scientific Days International 2022

Practical methods to permit the analysis of host biomarkers in resource-limited settings

Chandna A, Richard-Greenblatt M, Tustin R, Lee SJ, Kain KC,  et al.
2022-04-18 • American Journal of Tropical Medicine and Hygiene
2022-04-18 • American Journal of Tropical Medicine and Hygiene
Host biomarker testing can be used as an adjunct to the clinical assessment of patients with infections and might be particularly impactful in resource-constrained settings. Research on ...