In 2024, the World Health Organization released a report on Priorities for Research on Hypertension Care Delivery. This article provides its executiv...
IMPORTANCE The burden of diabetes is growing worldwide. The costs associated with diabetes put substantial pressure on patients and health budgets, especially in low- and middle-inco...
Loarec A, Carnimeo V, Molfino L, Kizito W, Muyindike WR, et al.
2018-11-16 • AIDS
2018-11-16 • AIDS
: A multicentric, retrospective case-series analysis (facility-based) in five sites across Kenya, Malawi, Mozambique, and Uganda screened HIV-positive adults for hepatitis C virus (HCV) ...
Venables E, Edwards JK, Baert S, Etienne W, Khabala K, et al.
2016-10-20 • PLOS One
2016-10-20 • PLOS One
INTRODUCTION The number of people on antiretroviral therapy (ART) for the long-term management of HIV in low- and middle-income countries (LMICs) is continuing to increase, along wit...
Bemelmans M, Baert S, Negussie E, Bygrave H, Biot M, et al.
2016-05-13 • Journal of the International AIDS Society
2016-05-13 • Journal of the International AIDS Society
Introduction: Counselling services are recommended by the World Health Organization and have been partially adopted by national HIV guidelines. In settings with a high HIV burden, patien...
Ehrenkranz PD, Baptiste SL, Bygrave H, Ellman T, Doi N, et al.
2019-05-29 • PLOS Medicine
2019-05-29 • PLOS Medicine
In a Policy Forum, Peter Ehrenkranz and colleagues discuss the contribution of CD4 and viral load testing to outcomes for people with HIV in low- and middle-income countries.
Oza S, Harris P, Ansbro E, Perel P, Frieden M, et al.
2020-05-20 • MSF Scientific Days International 2020
2020-05-20 • MSF Scientific Days International 2020
INTRODUCTION Globally, hypertension is responsible for approximately half of all heart disease and stroke deaths. Over 75% of these deaths occur in low- and middle-income countries. ...
Ford NP, Meintjes GA, Pozniak A, Bygrave H, Hill AM, et al.
2014-11-19 • Lancet Infectious Diseases
2014-11-19 • Lancet Infectious Diseases
For more than two decades, CD4 cell count measurements have been central to understanding HIV disease progression, making important clinical decisions, and monitoring the response to ant...
Duncombe C, Rosenblum S, Hellmann N, Holmes CB, Wilkinson LS, et al.
2015-02-16 • Tropical Medicine and International Health
2015-02-16 • Tropical Medicine and International Health
The delivery of HIV care in the initial rapid scale-up of HIV care and treatment was based on existing clinic-based models, which are common in highly resourced settings and largely undi...
2012-10-09 • Journal of the International AIDS Society
2012-10-09 • Journal of the International AIDS Society
Though the advantages of routine virological monitoring for patients on anti-retroviral therapy have been established, cost and complexity limit its full implementation. Monitoring is im...
Cohn J, Bygrave H, Roberts TR, Khan T, Ojji D, et al.
2022-04-12 • Global Heart
2022-04-12 • Global Heart
Hypertension is the most important risk factor for cardiovascular diseases (CVDs), which are the leading global cause of death. Hypertension is under-diagnosed and under-treated in most ...
Webster R, Murphy A, Bygrave H, Ansbro É, Grobbee DE, et al.
2019-12-31 • Global Heart
2019-12-31 • Global Heart
HIGHLIGHTS -- Despite clinical evidence of its effectiveness in secondary prevention of cardiovascular disease, uptake of fixed dose combination therapy (FDCs) for CVD has been poor....
Pannus P, Fajardo E, Metcalf CJ, Coulborn R M, Duran LT, et al.
2013-07-25 • Journal of Acquired Immune Deficiency Syndromes (1999)
2013-07-25 • Journal of Acquired Immune Deficiency Syndromes (1999)
: Rollout of routine HIV-1 viral load monitoring is hampered by high costs and logistical difficulties associated with sample collection and transport. New strategies are needed to overc...
Cohen RM, Lynch S, Bygrave H, Eggers E, Vlahakis N, et al.
2009-10-08 • Journal of the International AIDS Society
2009-10-08 • Journal of the International AIDS Society
ABSTRACT: INTRODUCTION: Lesotho has the third highest HIV prevalence in the world (an adult prevalence of 23.2%). Despite a lack of resources for health, the country has implemented stat...
Ndlovu M, Fajardo E, Mbofana F, Maparo TMS, Garone DB, et al.
2018-03-02 • PLOS One
2018-03-02 • PLOS One
HIV Viral Load and Early Infant Diagnosis technologies in many high burden settings are restricted to centralized laboratory testing, leading to long result turnaround times and patient ...