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Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 7 of 7 Items
Showing 1 - 7 of 7 Items
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Journal Article
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Letter

Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa

Carroll MW, Matthews DA, Hiscox JA, Elmore MJ, Pollakis G,  et al.
2015-06-17 • Nature
2015-06-17 • Nature
West Africa is currently witnessing the most extensive Ebola virus (EBOV) outbreak so far recorded. Until now, there have been 27,013 reported cases and 11,134 deaths. The origin of the ...
Journal Article
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Research

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

Sissoko D, Laouenan C, Folkesson E, M’Lebing A, Beavogui A,  et al.
2016-03-01 • PLOS Medicine
2016-03-01 • PLOS Medicine
Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the Ebola outbreak was at its peak, the World Health ...
Journal Article
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Short Report

Lactating mothers infected with Ebola virus: EBOV RT-PCR of blood only may be insufficient

Moreau M, Spencer C, Gozalbes JG, Colebunders R, Lefevre A,  et al.
2015-01-22 • Eurosurveillance
2015-01-22 • Eurosurveillance
Journal Article
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Research

Favipiravir Pharmacokinetics in Ebola-Infected Patients of the JIKI Trial Reveals Concentrations Lower Than Targeted

Nguyen TN, Guedj J, Anglaret X, Laouenan C, Madelain V,  et al.
2017-02-23 • PLOS Neglected Tropical Diseases
2017-02-23 • PLOS Neglected Tropical Diseases
In 2014-2015, we assessed favipiravir tolerance and efficacy in patients with Ebola virus (EBOV) disease (EVD) in Guinea (JIKI trial). Because the drug had never been used before for thi...
Journal Article
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Research

Unique human immune signature of Ebola Virus Disease in Guinea

Ruibal P, Oestereich L, Ludtke A, Becker-Ziaja B, Wozniak DM,  et al.
2016-05-04 • Nature
2016-05-04 • Nature
Despite the magnitude of the Ebola virus disease (EVD) outbreak in West Africa, there is still a fundamental lack of knowledge about the pathophysiology of EVD. In particular, very littl...
Journal Article
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Research

Deep sequencing of RNA from blood and oral swab samples reveals the presence of nucleic acid from a number of pathogens in patients with acute Ebola Virus Disease and Is consistent with bacterial translocation across the gut

Carroll MW, Haldenby S, Rickett NY, Palyi B, Garcia-Dorival I,  et al.
2017-08-30 • mSphere
2017-08-30 • mSphere
In this study, samples from the 2013-2016 West African Ebola virus outbreak from patients in Guinea with Ebola virus disease (EVD) were analyzed to discover and classify what other patho...
Journal Article
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Research

Field evaluation of capillary blood samples as a collection specimen for the rapid diagnosis of Ebola virus infection during an outbreak emergency

Strecker T, Palyi B, Ellerbrok H, Jonckheere S, De Clerck H,  et al.
2015-05-19 • Clinical Infectious Diseases
2015-05-19 • Clinical Infectious Diseases
Reliable reverse-transcriptase polymerase chain reaction (RT-PCR)-based diagnosis of Ebola virus infection currently requires a blood sample obtained by intravenous puncture. During the ...