Chotsiri P, Denoeud-Ndam L, Baudin E, Guindo O, Diawara H, et al.
2019-06-01 • Clinical Pharmacology & Therapeutics
2019-06-01 • Clinical Pharmacology & Therapeutics
Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub‐Saharan African children and may affect the pharmacology of antimalarial drugs....
Das D, Grais RF, Okiro EA, Stepniewska K, Mansoor R, et al.
2018-10-29 • BMC Medicine
2018-10-29 • BMC Medicine
Despite substantial improvement in the control of malaria and decreased prevalence of malnutrition over the past two decades, both conditions remain heavy burdens that cause hundreds of ...
Kloprogge F, Workman L, Borrmann S, Tekete M, Lefevre G, et al.
2018-06-12 • PLOS Medicine
2018-06-12 • PLOS Medicine
The fixed dose combination of artemether-lumefantrine (AL) is the most widely used treatment for uncomplicated Plasmodium falciparum malaria. Relatively lower cure rates and lumefantrine...
Pearce RJ, Pota H, Evehe M-SB, Ba EH, Mombo-Ngoma G, et al.
2009-04-14 • PLOS Medicine
2009-04-14 • PLOS Medicine
BACKGROUND: Although the molecular basis of resistance to a number of common antimalarial drugs is well known, a geographic description of the emergence and dispersal of resistance mutat...
Denoeud-Ndam L, Dicko A, Baudin E, Guindo O, Grandesso F, et al.
2015-06-12 • BMC Infectious Diseases
2015-06-12 • BMC Infectious Diseases
Malnutrition and malaria frequently coexist in sub-Saharan African countries. Studies on efficacy of antimalarial treatments usually follow the WHO standardized protocol in which severel...
Stepniewska K, Taylor WRJ, Mayxay M, Price RN, Smithuis FM, et al.
2004-11-01 • Antimicrobial Agents and Chemotherapy
2004-11-01 • Antimicrobial Agents and Chemotherapy
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with foll...
Lee SJ, Stepniewska K, Anstey NM, Ashley EA, Barnes KI, et al.
2008-08-01 • Malaria Journal
2008-08-01 • Malaria Journal
BACKGROUND: Malaria is a very important cause of anaemia in tropical countries. Anaemia is assessed either by measurement of the haematocrit or the haemoglobin concentration. For compari...
Stepniewska K, Ashley EA, Lee SJ, Anstey NM, Barnes KI, et al.
2010-02-15 • Journal of Infectious Diseases
2010-02-15 • Journal of Infectious Diseases
Parasite clearance data from 18,699 patients with falciparum malaria treated with an artemisinin derivative in areas of low (n=14,539), moderate (n=2077), and high (n=2083) levels of mal...
Taylor WRJ, Naw HK, Maitland K, Williams TN, Kapulu M, et al.
2018-01-18 • BMC Medicine
2018-01-18 • BMC Medicine
In 2012, the World Health Organization recommended blocking the transmission of Plasmodium falciparum with single low-dose primaquine (SLDPQ, target dose 0.25 mg base/kg body weight), wi...
