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Showing 1 - 7 of 7 Items
Showing 1 - 7 of 7 Items
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Journal Article
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Research

Prevalence and risk factors for hepatitis C virus infection in an informal settlement in Karachi, Pakistan

Alam R, Aslam K, Ahmed M, Isaakidis P
2023-09-20 • PLOS Global Public Health
2023-09-20 • PLOS Global Public Health
The burden of hepatitis C virus (HCV) infection in Pakistan is amongst the highest in the world. People living in slums are likely to be at high risk of infection. Here, we describe the ...
Journal Article
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Research

Cost-effectiveness of screening and treatment using direct-acting antivirals for chronic Hepatitis C virus in a primary care setting in Karachi, Pakistan

Mafirakureva N, Lim AG, Khalid GG, Aslam K, Campbell L,  et al.
2020-11-04 • Journal of Viral Hepatitis
2020-11-04 • Journal of Viral Hepatitis
Despite the availability of effective direct-acting antiviral (DAA) treatments for Hepatitis C virus (HCV) infection, many people remain undiagnosed and untreated. We assessed the cost-e...
Journal Article
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Research

From Risk to Care: The Hepatitis C Screening and Diagnostic Cascade in a Primary Health Care Clinic in Karachi, Pakistan—a Cohort Study

Khalid GG, Kyaw KWY, Bousquet C, Auat R, Dmytro Donchuk,  et al.
2018-12-28 • International Health
2018-12-28 • International Health
Background In the high-prevalence setting of Pakistan, screening, diagnosis and treatment services for chronic hepatitis C (CHC) patients are commonly offered in specialized facilities. ...
Journal Article
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Research

Determining the lower limit of detection required for HCV viral load assay for test of cure following direct-acting antiviral based treatment regimens: evidence from a global dataset

Morgan JR, Marsh E, Savinkina A, Shilton S, Shadaker S,  et al.
2022-03-12 • Journal of Viral Hepatitis
2022-03-12 • Journal of Viral Hepatitis
Achieving global elimination of hepatitis C virus requires a substantial scale-up of testing. Point-of-care HCV viral load assays are available as an alternative to laboratory-based assa...
Journal Article
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Research

Effects and cost of different strategies to eliminate hepatitis C virus transmission in Pakistan: a modelling analysis

Lim AG, Walker JG, Mafirakureva N, Khalid GG, Qureshi H,  et al.
2020-03-01 • Lancet Global Health
2020-03-01 • Lancet Global Health
BACKGROUND
The WHO elimination strategy for hepatitis C virus advocates scaling up screening and treatment to reduce global hepatitis C incidence by 80% by 2030, but little is known ...
Journal Article
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Commentary

Leaving no one behind: Towards equitable global elimination of hepatitis C

Dahl EH, Zahid H, Aslam K, Jafri W
2020-03-14 • Journal of Global Health
2020-03-14 • Journal of Global Health
Journal Article
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Case Report/Series

DAA treatment failures in a low-resource setting with a high burden of hepatitis C infections: a case series

Zahid H, Aslam K, Dahl EH, Abbassi W, Adan S,  et al.
2022-05-23 • Oxford Medical Case Reports
2022-05-23 • Oxford Medical Case Reports
Globally, 58 million people are living with hepatitis C virus (HCV) infection and 1.5 million new patients are infected every year. The advent of direct acting antivirals (DAAs) has revo...